Multiple acinic cell carcinoma

1985 ◽  
Vol 99 (11) ◽  
pp. 1183-1193 ◽  
Author(s):  
H. Gustafsson ◽  
B. Carlsöö
Keyword(s):  
Parotid Gland ◽  
Cell Carcinoma ◽  
Submaxillary Gland ◽  
Acinic Cell Carcinoma ◽  
Salivary Gland Tumours ◽  
Acinic Cell ◽  
Ultrastructural Characteristics ◽  
The Right ◽  
Parotid Gland Tumours ◽  
Left Parotid Gland

AbstractA case is presented of multiple acinic cell carcinoma, occurring synchronously in the left parotid gland and in the right submaxillary gland of a 75-year-old male patient. Fourteen cases of primary multiple acinic cell carcinoma have previously been reported, all bilateral parotid gland tumours. To our knowledge this is the first report of extraparotid localization of an acinic cell carcinoma in a patient presenting multiple salivary gland tumours. The histologic and ultrastructural characteristics of the tumours are described and a review of the literature is given.

Familial Occurrence of Acinic Cell Carcinoma of the Parotid Gland

1999 ◽  
Vol 123 (11) ◽  
pp. 1118-1120 ◽  
Author(s):  
Peter L. Depowski ◽  
Gavin Setzen ◽  
Alex Chui ◽  
Peter J. Koltai ◽  
James Dollar ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Cell Carcinoma ◽  
Acinic Cell Carcinoma ◽  
Familial Occurrence ◽  
Salivary Gland Neoplasm ◽  
Warthin Tumor ◽  
Lymphoepithelial Lesion ◽  
Acinic Cell ◽  
Left Parotid Gland

Abstract We report the familial occurrence of acinic cell carcinoma involving the parotid gland, the first such report of which we are aware. The familial occurrence of any salivary gland neoplasm is rare. Several reports are present in the literature, including pleomorphic adenoma, Warthin tumor, carcinoma of the submandibular gland, and malignant lymphoepithelial lesion. We report the case of a 35-year-old man who underwent excision of a left parotid gland acinic cell carcinoma. Eight years later, his daughter presented at the age of 16 years with a nontender parotid gland mass that was excised and found also to be acinic cell carcinoma. The histologic features of both neoplasms were typical of acinic cell carcinoma. While this may represent a coincidental event, the possibility that this familial occurrence is a manifestation of common genetic or environmental risk cannot be excluded.

Acinic cell carcinoma of the parotid gland

Cancer ◽  
1966 ◽  
Vol 19 (12) ◽  
pp. 1761-1772 ◽  
Author(s):  
Carl-Magnus Eneroth ◽  
Per Å. Jakobsson ◽  
Carl Blanck
Keyword(s):  
Parotid Gland ◽  
Cell Carcinoma ◽  
Acinic Cell Carcinoma ◽  
Acinic Cell

scholarly journals Dedifferentiated Acinic Cell Carcinoma of the Parotid Gland With Myoepithelial Features

2002 ◽  
Vol 126 (9) ◽  
pp. 1104-1105 ◽  
Author(s):  
Simonetta Piana ◽  
Alberto Cavazza ◽  
Corrado Pedroni ◽  
Rosa Scotti ◽  
Luigi Serra ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Cell Carcinoma ◽  
Clinical Course ◽  
Acinic Cell Carcinoma ◽  
Low Grade ◽  
High Grade ◽  
Epithelial Proliferation ◽  
Acinic Cell

Abstract Dedifferentiated acinic cell carcinoma of the salivary gland is an uncommon variant of acinic cell carcinoma, characterized by the coexistence of both an usual low-grade acinic cell carcinoma and a high-grade dedifferentiated component, as well as by an accelerated clinical course. We describe a case of acinic cell carcinoma of the parotid gland in a 67-year-old woman, which recurred 4 times after surgery and radiotherapy. The recurrences consisted of residual foci of acinic cell carcinoma intermingled with a high-grade epithelial proliferation; the latter was focally constituted by cells with morphologic and immunohistochemical features of myoepithelium.

Clinical characteristics of acinic cell carcinoma and secretory carcinoma of the parotid gland

2019 ◽  
Vol 276 (12) ◽  
pp. 3461-3466 ◽  
Author(s):  
Tetsuya Terada ◽  
Ryo Kawata ◽  
Keiki Noro ◽  
Masaaki Higashino ◽  
Shuji Nishikawa ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Cell Carcinoma ◽  
Clinical Characteristics ◽  
Acinic Cell Carcinoma ◽  
Secretory Carcinoma ◽  
Acinic Cell

Primary Pulmonary Acinic Cell Carcinoma: A Clinicopathological Study of 6 Cases and Literature Review

2019 ◽  
Vol 27 (6) ◽  
pp. 584-592 ◽  
Author(s):  
Ling Nie ◽  
Chunlei Zhou ◽  
Hongyan Wu ◽  
Qiang Zhou ◽  
Fanqing Meng
Keyword(s):  
Cell Carcinoma ◽  
Comprehensive Evaluation ◽  
Clinicopathological Features ◽  
Acinic Cell Carcinoma ◽  
Mitotic Figure ◽  
Neoplastic Cells ◽  
Acinic Cell ◽  
S 100 ◽  
The Difference ◽  
The Right

Primary pulmonary acinic cell carcinoma (ACC) is rare. The clinicopathological features are not identical to that of classic ACC that leads to misdiagnosis. In this article, we summarized the clinicopathological features of 25 such cases, including 6 cases in this series and additional 19 cases in the literature. Pulmonary ACCs showed an overwhelming solid growth pattern. The neoplastic cells had eosinophilic granular and clear cytoplasm in most cases and displayed basophilic cytoplasm in only 4 cases. Intratumoral fibrous septa, mitotic figure, necrosis, and psammoma bodies were observed in some cases. Prominent nuclear atypia and perineural invasion might suggest high-grade transformation, metastasis, and recurrence. The tumor cells were strongly positive for CK8/18 and negative for TTF-1, p63, S-100, mammaglobin, MUC5b, MUC5ac, and DOG1. CK7 was exclusively positive for neoplastic cells with ductal differentiation. Of the 25 included cases, 10 cases were initially misdiagnosed. The tumor was prone to involve the right bronchus. The patient outcome was favorable. The accurate diagnosis of primary pulmonary ACC relies on comprehensive evaluation of histological and immunohistochemical features and realization of the difference from classic ACC.

Acinic cell carcinoma of the parotid gland in childhood

1993 ◽  
Vol 27 (2) ◽  
pp. 187-191 ◽  
Author(s):  
F.M. Tucci ◽  
P.M. Bianchi ◽  
S. Bottero ◽  
P. Partipilo ◽  
V. Pierro
Keyword(s):  
Parotid Gland ◽  
Cell Carcinoma ◽  
Acinic Cell Carcinoma ◽  
Acinic Cell
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