Contralateral auditory brainstem response abnormalities in acoustic neuroma

1989 ◽  
Vol 103 (9) ◽  
pp. 835-838 ◽  
Author(s):  
D. A. Moffat ◽  
D. M. Baguley ◽  
D. G. Hardy ◽  
Y. N. Tsui
Keyword(s):  
Acoustic Neuroma ◽  
Auditory Brainstem Response ◽  
Tumour Size ◽  
Auditory Brainstem ◽  
Axial Tomography ◽  
Brainstem Compression ◽  
Wave Generator ◽  
Computed Axial Tomography ◽  
Brainstem Response ◽  
The Relationship

AbstractContralateral Auditory Brainstem Response (ABR) findings in a series of 79 patients with unilateral acoustic neuroma are presented. Sixty-four patients (81 per cent) had a normal contralateral ABR, thirteen (16.4 per cent) had latency abnormalities contralaterally and in two patients (206 per cent) no consistent responses could be recorded despite good hearing. Abnormalities in the contralateral ABR were analysed and five patients had abnormal III-V interwave intervals, in seven patients the I-III intervals were abnormal and in one patient, only the fifth wave was present and of abnormal latency. The tumour size was assessed by computed axial tomography (CT) and the relationship between tumour size and contralateral ABR findings established. Large tumours (>2.5 cm.) were associated with contralateral ABR abnormalities in 25.6 per cent of the patients, medium tumours (1.0-2.5 cm.) with ABR abnormalities in 14 per cent and there were no abnormalities in the small group (intracanalicular). The implications for interpretation of ABR recordings contralateral to an acoustic neuroma are discussed in relation to brainstem compression and its effect on the wave generator sites.

scholarly journals Normal Auditory Brainstem Response in Patients with Acoustic Neuroma

1989 ◽  
Vol 99 (1) ◽  
pp. 10???14 ◽  
Author(s):  
Steven A. Telian ◽  
Paul R. Kileny ◽  
John K. Niparko ◽  
John L. Kemink ◽  
Malcolm D. Graham
Keyword(s):  
Acoustic Neuroma ◽  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Brainstem Response

scholarly journals Auditory brainstem response demonstrates that reduced peripheral auditory input is associated with self-report of tinnitus

2019 ◽  
Author(s):  
Naomi Bramhall ◽  
Garnett McMillan ◽  
Frederick Gallun ◽  
Dawn Konrad-Martin
Keyword(s):  
Animal Models ◽  
Auditory Brainstem Response ◽  
Otoacoustic Emissions ◽  
Auditory Brainstem ◽  
Self Report ◽  
Auditory Input ◽  
Distortion Product ◽  
Brainstem Response ◽  
Temporal Bones ◽  
The Relationship

Tinnitus is one of the predicted perceptual consequences of cochlear synaptopathy, a type of age-, noise-, or drug-induced auditory damage that has been demonstrated in animal models to cause homeostatic changes in central auditory gain. Although synaptopathy has been observed in human temporal bones, assessment of this condition in living humans is limited to indirect non-invasive measures such as the auditory brainstem response (ABR). In animal models, synaptopathy is associated with a reduction in ABR wave I amplitude at suprathreshold stimulus levels. Several human studies have explored the relationship between wave I amplitude and tinnitus, with conflicting results. This study investigates the hypothesis that reduced peripheral auditory input due to synaptic/neuronal loss is associated with tinnitus. ABR wave I amplitude data from 193 individuals (43 with tinnitus (22%), 150 without tinnitus (78%)), who participated in up to three out of four different studies, were included in a logistic regression analysis to estimate the relationship between wave I amplitude and tinnitus at a variety of stimulus levels and frequencies. Statistical adjustment for sex and distortion product otoacoustic emissions was included in the analysis. The results suggest that smaller ABR wave I amplitudes are associated with an increased probability of reporting tinnitus.

Normal audiologic presentations in patients with acoustic neuroma: An evaluation using strict audiologic parameters

2000 ◽  
Vol 122 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Daniel D. Magdziarz ◽  
Richard J. Wiet ◽  
Elizabeth A. Dinces ◽  
Lois C. Adamiec
Keyword(s):  
Acoustic Neuroma ◽  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Normal Hearing ◽  
Speech Discrimination ◽  
Preoperative Test ◽  
Brainstem Response ◽  
Vestibular Symptoms ◽  
Interaural Differences ◽  
High Level

Although several studies have previously reported on patients presenting with “normal” audiologic parameters in acoustic neuroma, the present study is, to our knowledge, the first to exclusively examine in detail cases involving exceptionally stringent objective audiometric features. Of 369 patients with acoustic neuroma who were operated on between April 1980 and April 1997 by our group, 10 had strictly normal hearing, defined as follows: (1) pure-tone average < 20 dB; (2) speech discrimination score > 90%; and (3) interaural differences < 10 dB at every hertz level. A high level of audiologic functioning was found to significantly lower the sensitivity of auditory brainstem response in the detection of acoustic neuroma. Magnetic resonance imaging was the only preoperative test exhibiting 100% sensitivity in this setting. Thus, a high level of clinical suspicion appears warranted in any case involving unexplained unilateral audio-vestibular symptoms—including those instances in which strictly normal hearing parameters exist and are associated with negative auditory brainstem response findings.

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