Giant cell tumour of the temporal bone presenting as vertigo

1995 ◽  
Vol 109 (6) ◽  
pp. 538-541 ◽  
Author(s):  
W. G. McCluggage ◽  
G. B. McBride ◽  
W. J. Primrose ◽  
J. Cullan ◽  
E. J. McNaboe ◽  
...  

AbstractWe report a case of giant cell tumour of the temporal bone arising in a 31-year-old man. The presenting symptoms were unusual, being rotational vertigo, unilateral tinnitus, and hearing loss. A computed tomography (CT) scan showed a large mass within the right temporal bone and the infratemporal fossa. The radiological appearance was suggestive of an aggressive primary neoplasm arising within bone. Biopsy and subsequent resection showed a giant cell tumour of bone. The tumour was histological grade 1. At two-year follow-up, there was no evidence of tumour recurrence or metastasis.

2019 ◽  
Vol 14 (2) ◽  
pp. 503-506
Author(s):  
Avani Jain ◽  
Ishwar Singh ◽  
Ravi Shankar ◽  
Deepti Varshney

2018 ◽  
pp. bcr-2018-225095
Author(s):  
Duarte Rosa ◽  
Raquel Baptista Dias ◽  
João Cunha Salvador ◽  
Alexandra Borges

We report the case of a 74-year-old man with a giant cell tumour (GCT) of the right maxilla and pterygoid process. The patient presented to the maxillofacial and head and neck surgery clinic with an ulcerated lesion of the hard palate. Initial workup with CT revealed a mass within the right maxillary sinus and pterygoid process with associated bone expansion and erosion. Biopsy showed a GCT with mucosal ulceration. Two years after surgical resection, a follow-up CT revealed tumour recurrence involving the right pterygoid process and lateral pterygoid muscle. The patient was then proposed for therapy with denosumab. Under denosumab treatment, the lesion maintained stable dimensions and became sclerotic and heavily ossified.


Hand Surgery ◽  
2005 ◽  
Vol 10 (01) ◽  
pp. 97-100 ◽  
Author(s):  
Narayan Hulse ◽  
Stewart J. Watson

Giant cell tumour of the tendon sheath is uncommon in children. We describe this tumour arising from the right ring finger in an eight-year-old girl. Plane radiographs showed a soft tissue mass with erosion of the distal phalanx. The tumour was treated by surgical excision with good outcome.


2011 ◽  
Vol 2011 (oct27 1) ◽  
pp. bcr0720114560-bcr0720114560
Author(s):  
T. Weerasuriya ◽  
R. Swaminathan

VCOT Open ◽  
2019 ◽  
Vol 02 (02) ◽  
pp. e64-e69
Author(s):  
Margaux Blondel ◽  
Lucile Gros ◽  
Marie-Odile Semin ◽  
Maxence Delverdier ◽  
Sophie Palierne ◽  
...  

Abstract Case Description A 9-year-old neutered female mixed-breed dog was presented for the assessment of right pelvic limb lameness of 1-week duration. The lameness had progressed to non-weight bearing the day before presentation. Diagnostic Findings Radiographic examination of the right stifle joint revealed a large purely lytic lesion affecting the proximal metaphysis and epiphysis of the right tibia associated with a pathological fracture of the tibial plateau. These findings, combined with histological evaluation of a bone biopsy performed under ultrasound-guidance, were suggestive of a giant cell tumour of bone. Treatment and Outcome A limb-sparing procedure was attempted as first-line treatment. Curettage of the tumour was followed by coblation, and the defect was filled with polymethyl methacrylate bone cement. Physical and radiographic follow-up examinations 1, 2 and 3 months after surgery revealed improved functional outcome and minor progression of osteolysis. However, local recurrence was apparent 5 months after initial surgery and the limb was therefore amputated. Clinical Relevance Giant cell tumour of bone is rare in dogs. In humans, the traditional surgical management is curettage. This treatment was attempted here for the first time in a dog and the short-term outcome was satisfactory. However, in this particular case, local control of the tumour was unsuccessful.


Author(s):  
◽  

A 25-year old female patient was referred to our department with a mass at the level of the right temporomandibular joint (TMJ). The patient experienced symptoms of paroxysmal pain of the TMJ and weight loss. Magnetic resonance imaging (MRI) revealed a tumour in the right masticatory space extending into the right TMJ, with invasion of the temporal bone. Surgical resection of the mass and total TMJ replacement surgery with a custom-made pros-thesis were performed. Final histological diagnosis of the resected specimen showed a dif-fuse-type tenosynovial giant cell tumour (D-TGCT). The multidisciplinary team’s decision was to give adjuvant radiotherapy; however, the patient declined further treatment. At 6 months follow-up, the patient had an excellent recovery with no signs of tumour recurrence on MRI. This is the first described case of D-TGCT treated with total TMJ replacement sur-gery using a custom-made alloplastic device.


2021 ◽  
Vol 28 ◽  
pp. 221049172110211
Author(s):  
Farokh Wadia ◽  
Kshitij Chaudhary ◽  
Chetan Anchan ◽  
Seena George ◽  
Arjun Dhawale

While giant cell tumour of bone is a relatively common tumour in adults, it is exceedingly rare in children. Multicentric metachronous giant cell tumour is an even rarer presentation of this tumour in skeletally immature patients. We present here the challenges in management of this rare tumour. A 12-year-old girl presented with a giant cell tumour affecting four different bones sequentially, three times within a 3-year period. The disease first appeared in the right distal fibula, then a year later in ipsilateral talus and calcaneus and finally a year later, in the T5 vertebral body, all requiring surgical treatment. Our strategy was to manage this lesion aggressively based on the limited literature available and present our own long-term surveillance strategy. Our patient responded well to treatment each time and has remained disease-free for 24 months from her last surgery. This is a rare case of metachronous multicentric giant cell tumour of bone in a skeletally immature patient requiring aggressive treatment and surveillance.


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