Sensorineural hearing loss and ulcerative colitis

1997 ◽  
Vol 111 (3) ◽  
pp. 277-278 ◽  
Author(s):  
B. N. Kumar ◽  
R. M. Walsh ◽  
P. S. Wilson ◽  
W. V. Carlin
Keyword(s):  
Ulcerative Colitis ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Immunosuppressive Therapy ◽  
Bowel Disease ◽  
Good Control ◽  
Sensorineural Hearing ◽  
Immunological Tests ◽  
Inner Ear Disease ◽  
Autoimmune Inner Ear Disease

AbstractThe association of sensorineural hearing loss and ulcerative colitis is well documented and it is speculated that this is autoimmune in origin. A case in a 12-year-old boy is described, that initially responded to steroid therapy, but four years later resulted in bilateral, profound sensorineural hearing loss in spite of good control of his bowel disease. Immunological tests may provide a clue as to the aetiology of suspected cases of autoimmune inner ear disease. Immediate treatment with steroids with or without immunosuppressive therapy is essential as delay may lead to irreversible hearing loss.

Azathioprine in Combination with Steroids in the Treatment of Autoimmune Inner-Ear Disease

1993 ◽  
Vol 21 (4) ◽  
pp. 192-196 ◽  
Author(s):  
Aytac Saraçaydin ◽  
Sedat Katircioğlu ◽  
Sami Katircioğlu ◽  
M Can Karatay
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Inner Ear ◽  
Sensorineural Deafness ◽  
Sensorineural Hearing ◽  
Once Daily ◽  
Uncommon Disease ◽  
Inner Ear Disease ◽  
Pure Tones ◽  
Autoimmune Inner Ear Disease

A total of twelve patients with a relatively uncommon form of progressive sensorineural deafness (autoimmune innerear disease) were treated orally with 1 mg/kg azathioprine, once daily, and with 30 mg prednisolone, every other day, for 4 weeks. Statistically significant increases in the ability to hear pure tones or in discrimination on audiometry took place in 10/12 patients. This condition was initially described as ‘sensorineural hearing loss', but it is now clear that the term ‘autoimmune inner-ear disease’ is more appropriate since the vestibular compartment as well as the cochlear compartment is involved. This relatively uncommon disease is one of the few forms of sensorineural deafness that can be successfully treated.

scholarly journals Sudden Bilateral Sensorineural Hearing Loss Associated with HLA A1-B8-DR3 Haplotype

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
G. Psillas ◽  
M. Daniilidis ◽  
A. Gerofotis ◽  
K. Veros ◽  
A. Vasilaki ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Inner Ear ◽  
Cyclosporine A ◽  
Immunosuppressive Treatment ◽  
Clinical Manifestations ◽  
Sensorineural Hearing ◽  
High Dose ◽  
Inner Ear Disease ◽  
Autoimmune Inner Ear Disease

Sudden sensorineural hearing loss may be present as a symptom in systemic autoimmune diseases or may occur as a primary disorder without another organ involvement (autoimmune inner ear disease). The diagnosis of autoimmune inner ear disease is still predicated on clinical features, and to date specific diagnostic tests are not available. We report a case of bilateral sudden hearing loss, tinnitus, intense rotatory vertigo, and nausea in a female patient in which the clinical manifestations, in addition to raised levels of circulating immune complexes, antithyroglobulin antibodies, and the presence of the HLA A1-B8-DR3 haplotype, allowed us to hypothesize an autoimmune inner ear disease. Cyclosporine-A immunosuppressive treatment in addition to steroids helped in hearing recovery that occurred progressively with normalization of the hearing function after a five-month treatment. Cyclosporine-A could be proposed as a therapeutic option in case of autoimmune inner ear disease allowing the suspension of corticosteroids that, at high dose, expose patients to potentially serious adverse events.

Noise-Induced Autoimmune Sensorineural Hearing Loss

2003 ◽  
Vol 112 (7) ◽  
pp. 569-573 ◽  
Author(s):  
Reena Gupta ◽  
Robert T. Sataloff
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Inner Ear ◽  
Environmental Noise ◽  
Sudden Hearing Loss ◽  
Sensorineural Hearing ◽  
Autoimmune Conditions ◽  
Inner Ear Disease ◽  
Asymmetric Hearing Loss ◽  
Autoimmune Inner Ear Disease

Typically, autoimmune sensorineural hearing loss has been described as a slowly progressive, asymmetric hearing loss that is responsive to medications traditionally used in the treatment of other autoimmune conditions. These medications include steroids and cytotoxic drugs. Inciting factors in autoimmune inner ear disease are rarely cited. We describe a case of episodic sudden hearing loss triggered consistently by environmental noise. The hearing loss was responsive to steroids at the time of each occurrence and was determined to be autoimmune. This case raises questions about the relationship between autoimmune inner ear disease and sensitivity to environmental noise that warrant further research.

Sensorineural hearing loss associated with psoriatic arthritis

2004 ◽  
Vol 118 (11) ◽  
pp. 909-911 ◽  
Author(s):  
S. Srikumar ◽  
M.K. Deepak ◽  
S. Basu ◽  
B.N. Kumar
Keyword(s):  
Hearing Loss ◽  
Psoriatic Arthritis ◽  
Sensorineural Hearing Loss ◽  
Immunosuppressive Agents ◽  
Sudden Onset ◽  
Sensorineural Hearing ◽  
Presumptive Diagnosis ◽  
Inner Ear Disease ◽  
High Index Of Suspicion ◽  
Autoimmune Inner Ear Disease

Autoimmune inner ear disease is a well described entity. We report a case of sudden-onset sensorineural hearing loss in association with psoriatic arthritis, which has not been reported in the literature. The case satisfies the criteria for the presumptive diagnosis of autoimmune hearing loss. A high index of suspicion, with early diagnosis and aggressive treatment with steroids and/or immunosuppressive agents, is essential to prevent irreversible hearing loss. The condition of psoriatic arthritis must be added to the pantheon of autoimmune diseases that can lead to sensorineural hearing loss.

scholarly journals Fluctuating Sensorineural Hearing Loss

2019 ◽  
Vol 24 (3) ◽  
pp. 109-116 ◽  
Author(s):  
Hui Liu ◽  
Kunpeng Zhou ◽  
Xuemei Zhang ◽  
Kevin A. Peng
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Current Treatment ◽  
Sensorineural Hearing ◽  
Initial Presentation ◽  
Vestibular Aqueduct ◽  
Long Term Follow Up ◽  
Inner Ear Disease ◽  
Fluctuating Hearing Loss

Background: Several otologic conditions can present with fluctuating sensorineural hearing loss, including Ménière’s disease, autoimmune inner ear disease, and enlarged vestibular aqueduct. Although these 3 etiologies vary greatly, distinguishing between these conditions at initial presentation can be challenging. Furthermore, initial treatment of these conditions is often similar. In this review, we discuss historical and current perspectives on diagnosis and treatment of these conditions. Summary: A literature search was performed regarding fluctuating hearing loss, and current treatment of these etiologies of fluctuating hearing loss was summarized. Immediate measures at the onset of acute hearing loss include corticosteroid therapy, while preventative and chronic therapies, which can limit disease severity and frequency, vary based on the specific condition treated. Key Messages: Fluctuating hearing loss can represent a range of pathologies, but the precise etiology may not be clear at initial presentation. Timely treatment and long-term follow-up, along with appropriate diagnostics, are necessary to optimize long-term hearing.

Antigen non-specific immunological tests in progressive sensorineural hearing loss

1994 ◽  
Vol 251 (5) ◽  
pp. 275-277 ◽  
Author(s):  
M. Savastano ◽  
C. Raffael ◽  
C. Andreoli ◽  
G. De Francis
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Immunological Tests

Inner-ear obliteration in ulcerative colitis patients with sensorineural hearing loss

2007 ◽  
Vol 122 (8) ◽  
pp. 871-874 ◽  
Author(s):  
S Kariya ◽  
K Fukushima ◽  
Y Kataoka ◽  
S Tominaga ◽  
K Nishizaki
Keyword(s):  
Magnetic Resonance Imaging ◽  
Ulcerative Colitis ◽  
Hearing Loss ◽  
Magnetic Resonance ◽  
Sensorineural Hearing Loss ◽  
Inner Ear ◽  
Three Dimensional ◽  
Sensorineural Hearing ◽  
Resonance Imaging ◽  
Published Report

AbstractObjective:Systemic autoimmune diseases, including ulcerative colitis, may involve the inner ear. Several ulcerative colitis cases presenting with sensorineural hearing loss have been reported. We report the T2-weighted, three-dimensional, inner-ear magnetic resonance imaging findings in the inner ears of two such patients.Methods:Case reports and a review of the literature concerning autoimmune disease and sensorineural hearing loss are presented.Results:We describe two cases of ulcerative colitis with sensorineural hearing loss in which three-dimensional magnetic resonance imaging revealed obliteration of the inner ear. Those inner ears with obliteration had severe hearing loss, and responded poorly to steroid therapy.Conclusion:To our knowledge, there has been no previous published report of the T2-weighted, inner-ear magnetic resonance imaging findings of cases of ulcerative colitis with sensorineural hearing loss. This paper represents the first published report in the world literature of inner-ear obliteration in such patients. Three-dimensional magnetic resonance imaging is beneficial in elucidating the pathophysiology of the inner-ear involvement seen in ulcerative colitis.

scholarly journals A STUDY OF SENSORINEURAL HEARING LOSS IN PATIENTS OF INFLAMMATORY BOWEL DISEASE

2019 ◽  
Vol 6 (10) ◽  
pp. 736-740
Author(s):  
Souvagini Acharya ◽  
Deepakraj Venkatesan ◽  
Shraddha Laxmidhar Mohanty ◽  
Prachi Mohapatra
Keyword(s):  
Inflammatory Bowel Disease ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Bowel Disease ◽  
Sensorineural Hearing ◽  
Inflammatory Bowel
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