Ulcerative Colitis and Sensorineural Hearing Loss

1983 ◽  
Vol 5 (1) ◽  
pp. 95 ◽  
Author(s):  
Joshua Backon
2007 ◽  
Vol 122 (8) ◽  
pp. 871-874 ◽  
Author(s):  
S Kariya ◽  
K Fukushima ◽  
Y Kataoka ◽  
S Tominaga ◽  
K Nishizaki

AbstractObjective:Systemic autoimmune diseases, including ulcerative colitis, may involve the inner ear. Several ulcerative colitis cases presenting with sensorineural hearing loss have been reported. We report the T2-weighted, three-dimensional, inner-ear magnetic resonance imaging findings in the inner ears of two such patients.Methods:Case reports and a review of the literature concerning autoimmune disease and sensorineural hearing loss are presented.Results:We describe two cases of ulcerative colitis with sensorineural hearing loss in which three-dimensional magnetic resonance imaging revealed obliteration of the inner ear. Those inner ears with obliteration had severe hearing loss, and responded poorly to steroid therapy.Conclusion:To our knowledge, there has been no previous published report of the T2-weighted, inner-ear magnetic resonance imaging findings of cases of ulcerative colitis with sensorineural hearing loss. This paper represents the first published report in the world literature of inner-ear obliteration in such patients. Three-dimensional magnetic resonance imaging is beneficial in elucidating the pathophysiology of the inner-ear involvement seen in ulcerative colitis.


1997 ◽  
Vol 111 (3) ◽  
pp. 277-278 ◽  
Author(s):  
B. N. Kumar ◽  
R. M. Walsh ◽  
P. S. Wilson ◽  
W. V. Carlin

AbstractThe association of sensorineural hearing loss and ulcerative colitis is well documented and it is speculated that this is autoimmune in origin. A case in a 12-year-old boy is described, that initially responded to steroid therapy, but four years later resulted in bilateral, profound sensorineural hearing loss in spite of good control of his bowel disease. Immunological tests may provide a clue as to the aetiology of suspected cases of autoimmune inner ear disease. Immediate treatment with steroids with or without immunosuppressive therapy is essential as delay may lead to irreversible hearing loss.


2015 ◽  
Vol 6 (01) ◽  
pp. 077-079 ◽  
Author(s):  
Sinem Yazici ◽  
Gulcin Benbir ◽  
Birsen Ince

ABSTRACTUlcerative colitis (UC) is characterized by an inflammatory disorder of the gastrointestinal tract. Immune-mediated extraintestinal manifestations of UC have increasingly attracted attention in the literature recently, for which UC is now considered as a systemic disease. Neurologic involvement associated with UC is probably under-reported because of the unawareness of many physicians, although early recognition and treatment are crucial in preventing major morbidity and sequel. In this case report is presented a patient newly diagnosed as UC, who developed both sensorineural hearing loss and intractable status epilepticus that we suggest to have resulted from immune-mediated mechanisms.


2000 ◽  
Vol 25 (2) ◽  
pp. 143-145 ◽  
Author(s):  
B.N. Kumar ◽  
M.S.H. Smith ◽  
R.M. Walsh ◽  
J.R.B. Green

2015 ◽  
Vol 19 (12) ◽  
pp. 729-731 ◽  
Author(s):  
G. Casella ◽  
D. Corbetta ◽  
M. Zolezzi ◽  
C. Di Bella ◽  
V. Villanacci ◽  
...  

2003 ◽  
Vol 117 (3) ◽  
pp. 212-214 ◽  
Author(s):  
J. Mathews ◽  
S. Rao ◽  
B. N. Kumar

Inner ear involvement with sensorineural hearing loss (SNHL) has been reported in many autoimmune disorders including ulcerative colitis. The pathogenetic mechanism of hearing loss in ulcerative colitis is thought to be immune mediated. Diagnostic tests are being developed to identify inner ear autoantibodies, that may be the cause of such hearing loss. The only test that is currently available for clinical use is the Otoblot test. This, however, tests only for antibodies against bovine heat shock protein 70 which is only one of the many cross-reacting proteins against the inner ear in suspected immune-mediated hearing loss. The clinical response to steroid therapy is thus the mainstay in the diagnosis of immune-mediated hearing loss. This paper presents a series of patients with clinically suspected autoimmune hearing loss. Diagnostic assays for this condition are discussed along with a review of the recent advances in the pathogenesis and laboratory diagnosis of immune-mediated sensorineural hearing loss.


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