Paediatric granular cell tumour of the larynx: case report of laser resection with frozen section

2007 ◽  
Vol 121 (5) ◽  
pp. 506-509 ◽  
Author(s):  
C Holton ◽  
H E Cruickshank ◽  
A S High ◽  
K Maclennan ◽  
Z G G Makura

Granular cell tumours of the larynx are a very rare cause of persistent hoarse or husky voice in children. We report the case of a 13-year-old girl who presented with a three-year history of progressively huskier voice. We discuss the presentation, location and diagnosis of the tumour. In addition, we present a method of surgical treatment of the tumour, involving the hitherto unreported technique of laser excision and frozen section of the lesion.

1970 ◽  
Vol 3 (1) ◽  
pp. 28-30
Author(s):  
SM Khodeza ◽  
Nahar Begum ◽  
Nishat Begum

Vulvar granular cell tumours are uncommon neoplasms of neural origin. The clinical presentations, surgical findings and histology of Granular Cell Tumour (GCT) of the vulva in a 50 year old lady is presented. Although rare, this benign lesion must be considered in the differential diagnosis of the labia majora masses, such as Bartholin,s duct cyst, Lipoma, Papilloma, Hydradenoma and Fibroma. DOI: http://dx.doi.org/10.3329/akmmcj.v3i1.10111 AKMMCJ 2012; 3(1): 28-30


2018 ◽  
Vol 100 (4) ◽  
pp. e85-e87
Author(s):  
A Goetz ◽  
N Nweze ◽  
A Joshi ◽  
J Farma

We describe a unique presentation of a rare disease presentation of a granular cell tumour. A 36-year-old woman presents with a large symptomatic left flank mass that had been slowly increasing in size. Multiple synchronous subcutaneous masses were found at presentation on the left breast, right auricle and right cheek. After diagnosis of granular cell tumour by core needle biopsy, the masses were excised with histopathological and immunohistochemical analysis of both specimens confirming the presence of non-malignant granular cell tumours. Granular cell tumours are rare Schwann cell derived tumours that are typically asymptomatic and benign. These tumours are most often located in the head and neck, with multifocal disease present in approximately 5–16% of patients. Final pathology is necessary for diagnosis and frozen section is rarely helpful. Malignancy is present in approximately 2% of cases and can be diagnosed by the presence of a high mitotic rate, large nucleoli, necrosis, spindling and pleomorphism are other suspicious features. Granular cell tumours do not generally require adjuvant treatment. The mainstay of therapy is surgical resection with surveillance.


2016 ◽  
Vol 49 (4) ◽  
pp. 275
Author(s):  
P Appiah-Thompson ◽  
KK Baidoo

Pathology ◽  
2016 ◽  
Vol 48 ◽  
pp. S132
Author(s):  
Kais Kasem ◽  
Lakshmy Nandakumar ◽  
Mark Appleyard ◽  
Mahendra Singh

1993 ◽  
Vol 107 (10) ◽  
pp. 940-941 ◽  
Author(s):  
Abdalla M. Hamid ◽  
Abduljabbar Alshaikly

AbstractGranular cell tumour is a rare benign neoplasm, that can affect many parts of the body, as single or multiple lesions. It is more common in black people and females. Typically it occurs between the fourth and fifth decades of life, with the median age for the laryngeal variety as 36 years. About 30 to 50 per cent occur in the tongue and 30 per cent in the skin.A case of granular cell tumour of the larynx is reported in an eight-year-old girl, presenting with hoarseness of voice. She was successfully treated with local excision of the tumour. This tumour is rare in the larynx where it is more common in males than females although granular cell tumours are found more frequently in females generally.For these reasons the authors suspect that their case, of a laryngeal granular cell tumour occurring in an eight-year-old girl might be the youngest to be reported.


2019 ◽  
Vol 12 (3) ◽  
pp. e227510
Author(s):  
Cláudia Santos ◽  
Ana Virgínia Araújo ◽  
Helena Contente ◽  
Cláudia Branco

Granular cell tumours are rare neoplasms that may occur anywhere in the body. The most common locations are the oral cavity, skin and subcutaneous tissue, with only 8% of these tumours occurring at a gastrointestinal site. In the specific case of gastric granular cell tumours, only a few cases have been published until today. Granular cell tumours are usually benign; however, some malignant forms have been reported. Both endoscopic and surgical resection represent the treatment of choice. The authors report a new clinical case of a gastric granular cell tumour, treated with laparoscopic surgical resection, describing some endoscopic, imagiological and anatomopathological features.


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