scholarly journals Synchronous Lumbar Disc Herniation in Adult Twins. Case Report

2004 ◽  
Vol 31 (4) ◽  
pp. 554-557 ◽  
Author(s):  
Ratan Bhardwaj ◽  
Rajiv Midha
Keyword(s):  
Case Report ◽  
Disc Degeneration ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Genetic Factors ◽  
Lumbar Disc ◽  
Relevant Literature ◽  
Lumbar Disc Degeneration ◽  
Adult Twins

Objective:To report an unusual case of large synchronous lumbar disc herniation in adult twins.Methods:Case report and relevant literature review.Results:The authors report a case of adult female monozygotic twins who synchronously presented with huge lumbar disc herniation. Rather than being a curious coincidence, this case highlights the potential importance of hereditary factors in the causation of lumbar disc degeneration. The relevant literature regarding the role of genetic factors and their relationship to other risk factors in lumbar disc degeneration is reviewed and discussed.Conclusion:Synchronous lumbar disc herniation in adult twins is a rare event. It, however, sheds light on the role of genetic factors in disc degeneration.

scholarly journals Does the sagittal spinal profile differ between the elderly Chinese populations with and without lumbar disc herniation?

2021 ◽  
Author(s):  
Jipeng Song ◽  
Fumin Pan ◽  
Chao Kong ◽  
Xiangyao Sun ◽  
Yu Wang ◽  
...  
Keyword(s):  
Disc Degeneration ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Age Groups ◽  
Lumbar Disc Degeneration ◽  
Roussouly Classification ◽  
Asymptomatic Volunteers ◽  
Two Populations

Abstract Background The influence of spinopelvic morphology on the Chinese elderly LDH population was not clear. The purpose of this study is to explore its influence on the characteristics of lumbar disc herniation or degeneration. Methods 212 elderly patients with LDH and 213 asymptomatic volunteers were involved. Spinal parameters were measured on full-length X-ray and compared between two populations. In herniated group, sagittal profiles were determined according to the Roussouly classification, the degenerative grades, the herniated location and the number of intervertebral lumbar disc degeneration were evaluated from the L1 to S1 on MRI scans. The differences on them among Roussouly types were analyzed. Results There were no significant differences in BMI, the mean value of age and sex distribution between two populations. Patients were found to have significantly smaller TK, LL, and SS than those volunteers (p < 0.05), while contradicting observations on PT and TPA were obtained (p < 0.05). Roussouly type 1 and type 2 ( 50.4% and 28.7% respectively) are predominant in the LDH population and the proportion of type 1 in elderly LDH is further increased. Subjects with LDH in type 1 and 2 had lower mean herniated locations and fewer mean herniated numbers than those with type 3 and 4. Conclusions Sagittal spinopelvic parameters were found to be significantly different in elderly LDH patients and asymptomatic volunteers. There were significant differences in the Roussouly distribution among different age groups of LDH. Different Roussouly subtypes have different effects on lumbar disc degeneration and herniation.

scholarly journals Efficacy of percutaneous endoscopic lumbar discectomy for pediatric lumbar disc herniation and degeneration on magnetic resonance imaging: case series and literature review

2021 ◽  
Vol 49 (1) ◽  
pp. 030006052098668
Author(s):  
Ruei-Hong Lin ◽  
Hung-Chieh Chen ◽  
Hung-Chuan Pan ◽  
Hsien-Te Chen ◽  
Chien-Chun Chang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Disc Degeneration ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Lumbar Discectomy ◽  
Resonance Imaging ◽  
Lumbar Disc Degeneration ◽  
Endoscopic Lumbar Discectomy

Objective Pediatric lumbar disc herniation (LDH), although uncommon, causes significant pain, discomfort, and sometimes disability. We examined the efficacy of percutaneous endoscopic lumbar discectomy (PELD) for pediatric LDH and the degree of lumbar disc degeneration at 1 year after PELD. Methods We retrospectively reviewed the data of pediatric patients with LDH who underwent PELD from December 2007 to July 2018. The patients’ symptoms, physical examination findings, clinical images, visual analog scale (VAS) scores, Oswestry Disability Index (ODI), and perioperative results (blood loss, length of hospital stay, and complications) were obtained from the medical records. Lumbar disc degeneration was graded using the modified Pfirrmann grading system at the 1-year postoperative magnetic resonance imaging (MRI) examination. Results Six boys and four girls who underwent PELD were evaluated. The patients’ mean age was 15.6 years (range, 13–17 years). The mean VAS score for low back pain, mean VAS score for lower limb pain, and mean ODI preoperatively and 1 year postoperatively were 6.2 and 0.3, 6.9 and 0.5, and 20 and 0.1, respectively. MRI showed significant disc degeneration after PELD. Conclusions Treating pediatric LDH with PELD is safe and effective. It relieves pain and reduces disability. However, lumbar disc degeneration still occurs.

scholarly journals Correlation between Sagittal Morphology of Lower Lumbar Endplate and Degenerative Changes in Patients with Lumbar Disc Herniation

2020 ◽  
Author(s):  
Chongqing Xu ◽  
Mengchen Yin ◽  
Wen Mo
Keyword(s):  
Disc Degeneration ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Intervertebral Discs ◽  
Modic Changes ◽  
Observer Agreement ◽  
Imaging Data ◽  
Lumbar Disc Degeneration ◽  
Lower Lumbar

Abstract Background: As an important anatomic factor in the process of Lumbar disc herniation (LDH), the correlation between endplate sagittal morphology and intervertebral disc degeneration (IDD) is unclear. and research on imaging data of lumbar endplate in patients with LDH is still insufficient. Our study aimed to observe the morphological change of the lower lumbar endplate (L3-S1) in patients with LDH on magnetic resonance imaging (MRI), and analyze its correlation with the degree of IDD.Methods/Design: All 116 patients were included. Based on their MRI, we divided endplates into three types (concave, flat and irregular), assigned intervertebral discs with Grade I-V given 1-5 points successively according to Pfirrmann system, and determined whether there was Modic change of each endplate. The correlation between the morphology of endplate and the degree of IDD was analyzed.Results: There were excellent inter-observer agreement for each item we analyzed (ICC > 0.75). Concave endplate appeared most frequently (187, 53.7%) and mainly distributed in L3/4 and L4/5, while irregular endplate was the least common type (54, 15.5%) and mainly concentrated in L5/S1. The IDD degree of corresponding disc increased gradually from concave (3.27 ± 0.81) to irregular endplates (4.25 ± 0.79) (P < 0.05). Irregular endplates were more likely to have Modic changes than concave and flat endplates (P < 0.05). Conclusion: The sagittal morphology of lower lumbar endplate is related to Modic changes and degree of IDD (based on Pfirrmann grading system) in patients with LDH, and the concave endplate mostly reflects a lower degree of lumbar disc degeneration, which has substantial clinical significance.

The Role of Cyclooxygenase-2 in Lumbar Disc Herniation

Spine ◽  
2002 ◽  
Vol 27 (22) ◽  
pp. 2477-2483 ◽  
Author(s):  
Hiroshi Miyamoto ◽  
Ryuichi Saura ◽  
Minoru Doita ◽  
Masahiro Kurosaka ◽  
Kosaku Mizuno
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Cyclooxygenase 2

scholarly journals A Case Report of Lumbar Disc Herniation Migrated to Posterior Epidural Space Combined with Bladder Bowel Disturbance.

2001 ◽  
Vol 50 (4) ◽  
pp. 999-1003
Author(s):  
Shohei Matsubayashi ◽  
Takeshi Uchida ◽  
Naoyuki Yamamoto ◽  
Keisuke Sera
Keyword(s):  
Case Report ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Epidural Space ◽  
Lumbar Disc

scholarly journals Extruded Lumbar Disc Herniation with Spontaneous Reabsorption: Case Report and Review

2016 ◽  
Vol 35 (01) ◽  
pp. 070-073 ◽  
Author(s):  
Paulo Freitas ◽  
Matheus Fernandes ◽  
Matheus Gomes ◽  
Alex Spassim ◽  
Ademar Mesquita ◽  
...  
Keyword(s):  
Case Report ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc

scholarly journals Surgery for Recurrent Lumbar Disc Herniation During Pregnancy: A Case Report

2011 ◽  
Vol 8 (4) ◽  
pp. 304 ◽  
Author(s):  
Jae Meen Lee ◽  
In Ho Han ◽  
Soo Hyeon Moon ◽  
Byung Kwan Choi
Keyword(s):  
Case Report ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Recurrent Lumbar Disc Herniation

scholarly journals Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study

2011 ◽  
Vol 70 (10) ◽  
pp. 1740-1745 ◽  
Author(s):  
Gregory Livshits ◽  
Maria Popham ◽  
Ida Malkin ◽  
Philip N Sambrook ◽  
Alex J MacGregor ◽  
...  
Keyword(s):  
Risk Factors ◽  
Low Back Pain ◽  
Back Pain ◽  
Disc Degeneration ◽  
Genetic Factors ◽  
Lumbar Disc ◽  
Low Back ◽  
Lumbar Disc Degeneration ◽  
Sibling Pairs ◽  
Validated Questionnaire

ObjectiveLow back pain (LBP) is a common musculoskeletal disorder, but it is still unclear which individuals develop it. The authors examined the contribution of genetic factors, lumbar disc degeneration (LDD) and other risk factors in a female sample of the general population.Material and MethodsA cross-sectional study was conducted among 2256 women (371 and 698 monozygotic and dizygotic twin pairs and 29 sibling pairs and 60 singletons) with a mean age of 50 years (18–84). A self-reported validated questionnaire was used to collect back pain data. Risk factors including body weight, smoking, occupation, physical exercise and MRI assessed LDD were measured. Data analysis included logistic regression and variance decomposition.ResultsThe major factors associated with LBP included genetic background, with OR approximately 6 if the monozygotic co-twin had LBP, or 2.2 if she was a dizygotic co-twin. In addition, LDD and overweight were highly significantly (p<0.001) associated with non-specific LBP. The single most important risk factor was the amount of LDD. After adjustment for other risk factors, the individuals who exhibited advanced LDD (90% vs 10%) had 3.2 higher odds of manifesting LBP. The data also showed a significant (p<0.001) genetic correlation between the LBP and LDD measurements, suggesting that approximately 11–13% of the genetic effects are shared by LDD and LBP.ConclusionsThe main risk factors for reported episodes of severe and disabling LBP in UK women include the degree of LDD as assessed by MRI, being overweight and genetic heritability.

Lumbar disc herniation in early childhood: case report and literature review

2003 ◽  
Vol 19 (4) ◽  
pp. 258-260 ◽  
Author(s):  
Juan F. Martínez-Lage ◽  
Víctor Fernández Cornejo ◽  
Francisco López ◽  
Máximo Poza
Keyword(s):  
Early Childhood ◽  
Case Report ◽  
Literature Review ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc
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