scholarly journals Extradural Middle Fossa Approach to a Clear Cell Meningioma in a Child

Author(s):  
James King ◽  
Michael Cusimano ◽  
Cynthia Hawkins ◽  
Peter Dirks
2021 ◽  
Author(s):  
Walid I B N Essayed ◽  
Michael A Mooney ◽  
Ossama Al-Mefty

Abstract Preoperative careful evaluation of the sigmoid transverse sinus and its tributary veins is paramount for the safe surgical planning of petroclival lesions.1,2 When the vein of Labbé is running within the tentorium, classic petrosal approach involving transection of the tentorium is modified to avoid the risk of postoperative morbid temporal lobe venous infarcts.1-3 Thus, the surgical plan should be tailored to the specific patient anatomy as demonstrated in the presented case during which a transmastoid approach was followed, in the same surgical setting, by a middle fossa approach to resect a large petroclival clear cell meningioma with extension into Meckel cave. These meningiomas are WHO grade II tumors with a propensity to local recurrence and cerebrospinal fluid seeding.4 SMARCE1 mutations define this subtype of meningioma, with frequent familial inheritance, and predispose patients to both skull base and spinal clear cell meningiomas.5,6 Maximal surgical resection is the best initial treatment option allowing to withhold or delay the use of radiation in tumors frequently encountered in young patients.7 In this report, we demonstrate the microsurgical techniques deployed to achieve maximal resection of a petroclival clear cell meningioma and associated lumbar and sacral spinal meningiomas in a 20-yr-old patient with a familial SMARCE1 mutation. The patient agreed to the surgical intervention and to the use of her image.


1992 ◽  
Vol 25 (2) ◽  
pp. 347-359 ◽  
Author(s):  
William F. House ◽  
Clough Shelton

Skull Base ◽  
2005 ◽  
Vol 15 (S 2) ◽  
Author(s):  
Emilio García-Ibánez ◽  
Luis García-Ibánez ◽  
Elena Hernández ◽  
G. Martínez-Monche

Skull Base ◽  
2009 ◽  
Vol 19 (03) ◽  
Author(s):  
Raghuram Sampath ◽  
Chad Glenn ◽  
Shashikant Patil ◽  
Prasad Vannemreddy ◽  
Anil Nanda ◽  
...  

2009 ◽  
Vol 5 (4) ◽  
pp. 324 ◽  
Author(s):  
Prabal Deb ◽  
SubramanyaG.S Datta

2012 ◽  
Vol 28 (12) ◽  
pp. 2143-2151 ◽  
Author(s):  
Zhiqi Li ◽  
Yi Zhang ◽  
Enming Wang ◽  
Zhiqiu Wang ◽  
Wengang Li ◽  
...  

2017 ◽  
Vol 24 (3) ◽  
pp. 244
Author(s):  
B. Domingo-Arrué ◽  
R. Gil-Benso ◽  
J. Megías ◽  
L. Navarro ◽  
T. San-Miguel ◽  
...  

We report a case of a recurrent clear cell meningioma (ccm) in the frontal lobe of the brain of a 67-year-old man. The patient developed three recurrences: at 3, 10, and 12 years after his initial surgery. Histopathology observations revealed a grade 2 ccm with positivity for vimentin and epithelial membrane antigen. Expression of E-cadherin was positive only in the primary tumour and in the first available recurrence. Fluorescence in situ hybridization analyses demonstrated 1p and 14q deletions within the last recurrence. Multiplex ligation-dependent probe amplification studies revealed a heterozygous partial NF2 gene deletion, which progressed to total loss in the last recurrence. The last recurrence showed homozygous deletions in CDKN2A and CDKN2B. The RASSF1 gene was hypermethylated during tumour evolution.In this report, we show the genetic alterations of a primary ccm and its recurrences to elucidate their relationships with the changes involved in the progression of this rare neoplasm.


2017 ◽  
Vol 13 (4) ◽  
pp. 522-528 ◽  
Author(s):  
Kumar Abhinav ◽  
David Panczykowski ◽  
Wei-Hsin Wang ◽  
Carl H. Synderman ◽  
Paul A. Gardner ◽  
...  

Abstract BACKGROUND: The maxillary nerve (V2) can be approached via the open middle fossa approach. OBJECTIVE: To delineate the anatomy of V2 and its specific segments with respect to the endonasal landmarks. We present the endoscopic endonasal interdural middle fossa approach to V2 and its potential application for the treatment of perineural spread in sinonasal/skull base tumors. METHODS: Five human head silicon-injected specimens underwent bilateral endoscopic endonasal transpterygoid approaches. V2 prominence and the maxillary strut were identified in the lateral recess along with paraclival carotid protruberance. The regions superior and inferior to V2 corresponding to the anteromedial and anterolateral triangles of the middle fossa were exposed. RESULTS: V2 can be classified into 3 segments: interdural (from the Gasserian ganglion to the proximal part of the maxillary strut), intracanalicular (corresponding to the anteroposterior length of the maxillary strut), and pterygopalatine (distal to the maxillary strut and the site of its divisions). Endonasally, the average length of the interdural and the intracanalicular segments were approximately 9 and 4.4 mm, respectively. V2, following its division distal to the maxillary strut, was successfully dissected off the middle fossa dura and transected just distal to the Gasserian ganglion. CONCLUSION: Endonasally, the interdural segment can be safely mobilized between the periosteal and meningeal dural layers while ensuring the integrity of the middle fossa dura. This allows transection of infiltrated V2 to facilitate tumor resection without entering the intradural/arachnoidal space. Posteriorly, this is limited by the Gasserian ganglion and superomedially by the dural envelope surrounding the cavernous sinus and the paraclival carotid artery.


2005 ◽  
Vol 102 (3) ◽  
pp. 303-306 ◽  
Author(s):  
Edward S. Ahn ◽  
Lawrence S. Chin ◽  
Kymberly A. Gyure ◽  
Richard S. Hudes ◽  
John Ragheb ◽  
...  

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