Lectin Binding to Human Breast Tumor Cells

1976 ◽  
Vol 34 ◽  
pp. 34-35
Author(s):  
Robert E. Nordquist ◽  
J. Hill Anglin ◽  
Michael P. Lerner
Keyword(s):  
Carcinoma Cell ◽  
Ricinus Communis ◽  
Lectin Binding ◽  
Low Frequency ◽  
Breast Carcinoma Cell Line ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Duct Carcinoma ◽  
Specific Antigens ◽  
Ricin Agglutinin

A human breast carcinoma cell line (BOT-2) was derived from an infiltrating duct carcinoma (1). These cells were shown to have antigens that selectively bound antibodies from breast cancer patient sera (2). Furthermore, these tumor specific antigens could be removed from the living cells by low frequency sonication and have been partially characterized (3). These proteins have been shown to be around 100,000 MW and contain approximately 6% hexose and hexosamines. However, only the hexosamines appear to be available for lectin binding. This study was designed to use Concanavalin A (Con A) and Ricinus Communis (Ricin) agglutinin for the topagraphical localization of D-mannopyranosyl or glucopyranosyl and D-galactopyranosyl or DN- acetyl glactopyranosyl configurations on BOT-2 cell surfaces.

scholarly journals UBE2Q1 in a Human Breast Carcinoma Cell Line: Overexpression and Interaction with p53

2015 ◽  
Vol 16 (9) ◽  
pp. 3723-3727 ◽  
Author(s):  
Sayed Mohammad Shafiee ◽  
Mozhgan Rasti ◽  
Atefeh Seghatoleslam ◽  
Tayebeh Azimi ◽  
Ali Akbar Owji
Keyword(s):  
Breast Carcinoma ◽  
Cell Line ◽  
Carcinoma Cell ◽  
Human Breast Carcinoma ◽  
Carcinoma Cell Line ◽  
Breast Carcinoma Cell Line ◽  
Human Breast ◽  
Human Breast Carcinoma Cell

Synthesis of novel pyrazole derivatives using organophosphorus, stibine, and arsine reagents and their antitumor activities

2016 ◽  
Vol 71 (7) ◽  
pp. 765-776 ◽  
Author(s):  
Naglaa F. El-Sayed ◽  
Ewies F. Ewies ◽  
Marwa El-Hussieny ◽  
Leila S. Boulos ◽  
ElSayed M. Shalaby
Keyword(s):  
Cell Line ◽  
Carcinoma Cell ◽  
New Products ◽  
Carcinoma Cell Line ◽  
Breast Carcinoma Cell Line ◽  
Human Breast ◽  
Antitumor Activities ◽  
Hepatocellular Carcinoma Cell Line ◽  
Human Hepatocellular Carcinoma Cell ◽  
Structural Reasoning

AbstractThe reactions of 5-azido-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde (azidopyrazole) with several classes of organophosphorus reagents: phosphonium ylides, Wittig-Horner reagents, dialkylphosphonates, trialkylphosphites, tris(dialkylamino)phosphanes, triphenylstibane, triphenylarsane, and Lawesson’s reagent are reported. Structural reasoning for the new products was based on compatible analytical and spectral data. The cytotoxic activity of most of the new products was evaluated against human breast carcinoma cell line (MCF7) and human hepatocellular carcinoma cell line(HepG2). Certain tested compounds showed promising results.

Increased proliferation of a human breast carcinoma cell line by recombinant interleukin-2

1994 ◽  
Vol 39 (3) ◽  
pp. 161-166 ◽  
Author(s):  
Tatsuya Matsuo ◽  
Takashi Morisaki ◽  
Keiko Naito ◽  
Fumio Nagumo ◽  
Eiro Kubota ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Cell Line ◽  
Carcinoma Cell ◽  
Interleukin 2 ◽  
Human Breast Carcinoma ◽  
Carcinoma Cell Line ◽  
Breast Carcinoma Cell Line ◽  
Human Breast ◽  
Human Breast Carcinoma Cell ◽  
Recombinant Interleukin 2
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