Observations on the ultrastructure of inguinal cryptorchid testis in children

1994 ◽  
Vol 52 ◽  
pp. 256-257
Author(s):  
I. Bane Hani ◽  
A. Abalkhail ◽  
F. Al-Bagdadi ◽  
Y. Abu-Ghalyun
Keyword(s):  
Early Detection ◽  
Teaching Hospital ◽  
Early Detection Of Cancer ◽  
Undescended Testis ◽  
Surgical Correction ◽  
Ultrastructural Changes ◽  
Testicular Tumors ◽  
Cryptorchid Testis ◽  
The Difference ◽  
Morphological Differences

Cryptorchidism is most frequently reported in horses, swine, and man. Neoplasia has been documented in the descended testes of unilateral cryptorchid testes in children. It has been reported that 10% of the testicular tumors in humans were associated with cryptorchidism. Most of the reported information did not specify the difference between inguinal and abdominal cryptorchid testes. Recently histological and ultrastructural morphological differences have been reported. The spermatoginia of many cryptorchid males bear a congenital lesion. It has been recommended that screening children for early detection of cancer, with undescended testis will reduce cancer. The purpose of this investigation is to characterize the ultrastructural changes of inguinal cryptorchid testes of children at different ages, treated at Princess Basmah teaching Hospital at Irbid, Jordan. It is anticipated that this study will provide information for timing decision for surgical correction. Children with cryptorchid testis between one and thirteen years old were presented to Princess Basmah teaching hospital.

scholarly journals Barriers to implementation of guidelines for the diagnosis and management of undescended testis

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 326 ◽  
Author(s):  
Shawn C. Smith ◽  
Hiep T. Nguyen
Keyword(s):  
Early Detection ◽  
Gold Standard ◽  
Undescended Testis ◽  
Surgical Correction ◽  
International Studies ◽  
American Urologic Association ◽  
Diagnosis And Management ◽  
The Us ◽  
Barriers To Implementation ◽  
Common Barriers

Cryptorchidism or undescended testis (UDT) is one of the most common genital disorders identified at birth. The gold standard for treatment in the US is to surgically bring the UDT into the scrotal sac. In 2014, the American Urologic Association (AUA) presented a guideline for evaluation and treatment of cryptorchidism. We reviewed some of the most recent domestic and international studies examining the results of implementing the AUA and similar guidelines for the diagnosis and management of UDT. In addition, we reviewed some of the more common barriers to the implementation of the AUA guidelines and offered recommendations on how to increase the rate of early detection of UDT, thereby increasing the rate of surgical correction at the appropriate age.

Patented Biomarker Panels in Early Detection of Cancer

2011 ◽  
Vol 1 (1) ◽  
pp. 10-24 ◽  
Author(s):  
Monica Neagu ◽  
Carolina Constantin ◽  
Cristiana Tanase ◽  
Daniel Boda
Keyword(s):  
Early Detection ◽  
Early Detection Of Cancer

Development of a fluorescence video endoscopy imaging system for the early detection of cancer in the gastrointestinal tract

1997 ◽  
Author(s):  
Haishan Zeng ◽  
Alan Weiss ◽  
Calum E. MacAulay ◽  
Nick MacKinnon ◽  
Richard W. Cline ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Early Detection ◽  
Early Detection Of Cancer ◽  
Imaging System ◽  
Video Endoscopy

How Well were Asthmatic Patients Educated about Their Asthma? A Study at the Emergency Department

2004 ◽  
Vol 16 (1) ◽  
pp. 45-49 ◽  
Author(s):  
P.Y. Lee ◽  
E.M. Khoo
Keyword(s):  
Emergency Department ◽  
Health Care Providers ◽  
Teaching Hospital ◽  
Care Providers ◽  
Self Medication ◽  
Asthmatic Patients ◽  
Management Plans ◽  
Acute Asthma Exacerbation ◽  
The Difference ◽  
Bronchodilator Treatment

70 patients presented with acute asthma exacerbation requiring nebulised bronchodilator treatment at the emergency department of a teaching hospital in Kuala Lumpur, Malaysia, were interviewed over a two-week period in July 2001. The results showed that 45 (64%) patients had not been educated on the nature of asthma; 30 (43%) had not been advised on preventive measures or avoidance of triggers; 54 (77%) were not advised about the medications used and their side effects; 42 (60%) patients did not know the difference between reliever and preventive medications; 37 (53%) were unable to recognize features of worsening asthma and 68 (97%) were not told about the danger of non-prescribed self-medication or traditional medications. Only six (9%) patients were using peak flow meters and were taught self-management plans. The multiple regression results suggest that patients who were followed up at teaching hospital based clinics were better educated on asthma. In conclusion, asthmatic patients are still not educated well about their disease. Health care providers need to put more emphasis on asthma education so that the number of emergency room visits can be reduced. Asia Pac J Public Health 2004; 16(1): 45-49.

scholarly journals Early Detection of Cancer: Evaluation of MR Imaging Grading Systems in Patients with Suspected Nasopharyngeal Carcinoma

2020 ◽  
Vol 41 (3) ◽  
pp. 515-521 ◽  
Author(s):  
A.D. King ◽  
J.K.S. Woo ◽  
Q.-Y. Ai ◽  
F.K.F. Mo ◽  
T.Y. So ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Early Detection ◽  
Mr Imaging ◽  
Early Detection Of Cancer ◽  
Grading Systems

Early detection of cancer

1989 ◽  
Vol 5 (3) ◽  
pp. 151-152
Author(s):  
Loren J. Humphrey
Keyword(s):  
Early Detection ◽  
Early Detection Of Cancer

scholarly journals Methylation as a critical epigenetic process during tumor progressions among Iranian population: an overview

2021 ◽  
Vol 43 (1) ◽  
Author(s):  
Iman Akhlaghipour ◽  
Amir Reza Bina ◽  
Mohammad Reza Abbaszadegan ◽  
Meysam Moghbeli
Keyword(s):  
Risk Factors ◽  
Early Detection ◽  
Tumor Progression ◽  
Cancer Patients ◽  
Early Detection Of Cancer ◽  
Iranian Population ◽  
Molecular Diagnostic ◽  
Genomic Changes ◽  
Incidence And Mortality ◽  
Transcriptional Alterations

AbstractCancer is one of the main health challenges and leading causes of deaths in the world. Various environmental and genetic risk factors are associated with tumorigenesis. Epigenetic deregulations are also important risk factors during tumor progression which are reversible transcriptional alterations without any genomic changes. Various mechanisms are involved in epigenetic regulations such as DNA methylation, chromatin modifications, and noncoding RNAs. Cancer incidence and mortality have a growing trend during last decades among Iranian population which are significantly related to the late diagnosis. Therefore, it is required to prepare efficient molecular diagnostic panels for the early detection of cancer in this population. Promoter hyper methylation is frequently observed as an inhibitory molecular mechanism in various genes associated with DNA repair, cell cycle regulation, and apoptosis during tumor progression. Since aberrant promoter methylations have critical roles in early stages of neoplastic transformations, in present review we have summarized all of the aberrant methylations which have been reported during tumor progression among Iranian cancer patients. Aberrant promoter methylations are targetable and prepare novel therapeutic options for the personalized medicine in cancer patients. This review paves the way to introduce a non-invasive methylation specific panel of diagnostic markers for the early detection of cancer among Iranians.

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