The prediction of response in the anxiety disorders

1996 ◽  
Vol 8 (4) ◽  
pp. 102-104 ◽  
Author(s):  
B.R. Slaap ◽  
I.M. van Vliet ◽  
H.G.M. Westenberg ◽  
J.A. den Boer

SummaryIn this review the results are discussed on the prediction of response to pharmacotherapy in panic disorder (PD) and social phobia (SP). From the literature it appears that in PD variables indicative of illness severity are predictors of non-response. In our own studies we found that non-responders to pharmacotherapy in PD are characterised by a higher score on the Blood-Injury subscale of the Fear Questionnaire, a higher plasma MHPG and a higher heart rate. In SP non-responders to pharmacotherapy were also characterised by a higher heart rate. They also appeared to have a higher blood pressure. Furthermore non-responders to pharmacotherapy in SP had higher scores on several psychometric scales, indicative of illness severity.

2010 ◽  
Vol 72 (5) ◽  
pp. 442-449 ◽  
Author(s):  
Jose M. Martinez ◽  
Amir Garakani ◽  
Horacio Kaufmann ◽  
Cindy J. Aaronson ◽  
Jack M. Gorman

2015 ◽  
Vol 18 ◽  
Author(s):  
Francisco J. Labrador ◽  
Francisco J. Estupiñá ◽  
Mónica Bernaldo-de-Quirós ◽  
Ignacio Fernández-Arias ◽  
Pablo Alonso ◽  
...  

AbstractPeople with anxiety disorders demand psychological attention most often. Therefore, it seems important to identify both the characteristics of the patients who demand help and the clinical variables related to that demand and its treatment. A cohort of 292 patients who requested help at a university clinical facility was studied. The typical profile of the patient was: being female, young, unmarried, with some college education, and having previously received treatment, especially pharmacological one. The three most frequent diagnoses of anxiety, which include 50% of the cases, were: Anxiety Disorder not otherwise specified, Social Phobia, and Panic Disorder with Agoraphobia. Regarding the characteristics of the intervention, the average duration of the assessment was 3.5 sessions (SD = 1.2), and the duration of the treatment was 14 sessions (SD = 11.2). The percentage of discharges was 70.2%. The average cost of treatment was around €840. The results are discussed, underlining the value of empirically supported treatments for anxiety disorders.


1996 ◽  
Vol 59 (3) ◽  
pp. 183-188 ◽  
Author(s):  
Murray B Stein ◽  
Richard L Hauger ◽  
Ken S Dhalla ◽  
Mariette J Chartier ◽  
Gordon J.G Asmundson

Author(s):  
Altanzul Narmandakh ◽  
Annelieke M. Roest ◽  
Peter de Jonge ◽  
Albertine J. Oldehinkel

Abstract Anxiety disorders are a common problem in adolescent mental health. Previous studies have investigated only a limited number of risk factors for the development of anxiety disorders concurrently. By investigating multiple factors simultaneously, a more complete understanding of the etiology of anxiety disorders can be reached. Therefore, we assessed preadolescent socio-demographic, familial, psychosocial, and biological factors and their association with the onset of anxiety disorders in adolescence. This study was conducted among 1584 Dutch participants of the TRacking Adolescents’ Individual Lives Survey (TRAILS). Potential risk factors were assessed at baseline (age 10–12), and included socio-demographic (sex, socioeconomic status), familial (parental anxiety and depression), psychosocial (childhood adversity, temperament), and biological (body mass index, heart rate, blood pressure, cortisol) variables. Anxiety disorders were assessed at about age 19 years through the Composite International Diagnostic Interview (CIDI). Univariate and multivariate logistic regression analyses were performed with onset of anxiety disorder as a dependent variable and the above-mentioned putative risk factors as predictors. Of the total sample, 25.7% had a lifetime diagnosis of anxiety disorder at age 19 years. Anxiety disorders were twice as prevalent in girls as in boys. Multivariate logistic regression analysis showed that being female (OR = 2.38, p < .01), parental depression and anxiety (OR = 1.34, p = .04), temperamental frustration (OR = 1.31, p = .02) and low effortful control (OR = 0.76, p = .01) independently predicted anxiety disorders. We found no associations between biological factors and anxiety disorder. After exclusion of adolescents with an onset of anxiety disorder before age 12 years, being female was the only significant predictor of anxiety disorder. Being female was the strongest predictor for the onset of anxiety disorder. Psychological and parental psychopathology factors increased the risk of diagnosis of anxiety, but to a lesser extent. Biological factors (heart rate, blood pressure, cortisol, and BMI), at least as measured in the present study, are unlikely to be useful tools for anxiety prevention and intervention strategies.


2001 ◽  
Vol 14 (4) ◽  
pp. 209-213 ◽  
Author(s):  
Michael W. Otto ◽  
Mark H. Pollack ◽  
Kristin M. Maki ◽  
Robert A. Gould ◽  
John J. Worthington ◽  
...  

2005 ◽  
Vol 33 (2) ◽  
pp. 177-188 ◽  
Author(s):  
Richard Thwaites ◽  
Mark H. Freeston

Safety-seeking behaviours are seen as playing a key role in the maintenance of various anxiety disorders. This article examines their role in panic disorder and social phobia and suggests that, whilst there are clear theoretical differences between safety-seeking behaviours and adaptive coping strategies, the difficult issue in clinical practice is being able to distinguish between the two. It builds on previous work by Salkovskis and colleagues and provides a detailed discussion of the problems in distinguishing between safety-seeking behaviours (direct avoidance, escape and subtle avoidance) and adaptive coping strategies in clinical practice. The suggestion is made that topology can only be a guide to categorizing the two types of responses and they can only be fully distinguished by taking into account the intention of the individual and their perceived function to that individual in the specific context. It is suggested that further analysis of the use of safety-seeking behaviours aimed at avoiding a variety of outcomes at differing levels of catastrophe may provide useful information that would clarify our understanding of the role of such behaviours in maintaining anxiety disorders.


1999 ◽  
Vol 84 (3) ◽  
pp. 843-854 ◽  
Author(s):  
Jan K. van Niekerk ◽  
André T. Möller ◽  
Charl Nortje

A modified Stroop color-naming task was used to investigate whether social phobia and panic disorder are associated with a hypervigilance to social and physical threat-related cues, respectively, as predicted by Beck's cognitive theory of anxiety disorders. Color-naming latencies of 13 individuals with social phobia and 15 with panic disorder for words representing social and physical threats, respectively, were compared to matched neutral control words. The results did not support the hypothesis that the self-schemas of individuals with panic disorder are hypersensitive to information association with physical threat and that persons with social phobia are overly concerned with social threat.


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