scholarly journals Respiratory syncytial virus infection and meningococcal disease

1996 ◽  
Vol 117 (1) ◽  
pp. 107-111 ◽  
Author(s):  
J. M. Stuart ◽  
K. Cartwright ◽  
N. J. Andrews
Keyword(s):  
Time Series ◽  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Meningococcal Disease ◽  
Respiratory Tract Infections ◽  
Seasonal Component ◽  
Syncytial Virus ◽  
Tract Infections ◽  
Viral Respiratory ◽  
Do So

SummaryAlthough viral respiratory tract infections may predispose to meningococcal disease, strong evidence that they do so exists only for influenza. Data on laboratory reported cases of respiratory syncytial virus (RSV) infections and meningococcal disease in England and Wales from mid-1989 to mid-1994 were analysed. Although the rise in RSV cases preceded the rise in meningococcal disease cases each winter, the interval between the rise and fall of the two diseases was inconsistent, no association was found between time series after removal of the seasonal component, and there was no evidence that more cases of meningococcal disease occurred in winters with more RSV disease. RSV may have less effect on the two most likely mechanisms whereby influenza predisposes to meningococcal disease, namely lowered immunity and impaired pharyngeal defences.

scholarly journals Respiratory syncytial virus neutralizing activity in nasopharyngeal secretions

1970 ◽  
Vol 68 (4) ◽  
pp. 581-588 ◽  
Author(s):  
R. Scott ◽  
P. S. Gardner
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Virus Infections ◽  
Lower Respiratory Tract Infections ◽  
Neutralizing Activity ◽  
Previous Infection ◽  
Syncytial Virus ◽  
Tract Infections

SUMMARYNasopharyngeal secretions were taken during the acute phase of illness from 30 children admitted to hospital with lower respiratory tract infections. The presence of neutralizing activity in secretions taken at the onset of illness was demonstrated in 11 out of 15 patients (73%) with bronchiolitis caused by R.S. virus, as compared with 4 out of 9 patients (44%) with R.S. virus infections other than bronchiolitis, and 1 out of 6 without R.S. virus infection. Second secretions were taken 7 days later from 10 of the children with R.S. virus infection. Eight of these paired secretions showed an increase of neutralizing activity against R.S. virus. It is suggested that the neutralizing activity, found in secretions taken at the onset of illness, may be a result of previous infection with R.S. virus.

scholarly journals Extracellular amoebal-vesicles: potential transmission vehicles for respiratory viruses

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Rafik Dey ◽  
Melanie A. Folkins ◽  
Nicholas J. Ashbolt
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Respiratory Viruses ◽  
Environmental Persistence ◽  
Viral Dissemination ◽  
Acute Respiratory Tract Infections ◽  
High Concentrations ◽  
Syncytial Virus ◽  
Tract Infections

AbstractHuman respiratory syncytial virus (RSV) is a major cause of acute respiratory tract infections in children and immunocompromised adults worldwide. Here we report that amoebae-release respirable-sized vesicles containing high concentrations of infectious RSV that persisted for the duration of the experiment. Given the ubiquity of amoebae in moist environments, our results suggest that extracellular amoebal-vesicles could contribute to the environmental persistence of respiratory viruses, including potential resistance to disinfection processes and thereby offering novel pathways for viral dissemination and transmission.

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