Childhood maltreatment affects adolescent sensitivity to parenting and close friendships in predicting growth in externalizing behavior

2018 ◽  
Vol 31 (04) ◽  
pp. 1237-1253 ◽  
Author(s):  
Irene Tung ◽  
Amanda N. Noroña ◽  
Steve S. Lee
Keyword(s):  
Substance Use ◽  
Transition To Adulthood ◽  
Childhood Maltreatment ◽  
Externalizing Behavior ◽  
Multiple Testing ◽  
Violent Behavior ◽  
Growth Curves ◽  
Polygenic Risk Score ◽  
Latent Growth Curves ◽  
Parental Closeness

AbstractChildhood maltreatment robustly predicts adolescent externalizing behaviors (EB; e.g., violence, delinquency, substance use) and may crystalize patterns of EB by influencing sensitivity to the social environment (e.g., parenting, friendships). In a nationally representative sample of 9,421 adolescents, we modeled latent growth curves of EB from age 13 to 32 years. Next, we explored whether maltreated youth differed from nonmaltreated youth in their sensitivity to parental closeness, friendship involvement, and polymorphisms from dopamine genes linked to EB (dopamine receptors D2 and D4, dopamine transporter). Overall, maltreated youth had significantly higher levels of EB across adolescence and adulthood; however, maltreated and nonmaltreated youth showed similar patterns of EB change over time: violent behavior decreased in adolescence before stabilizing in adulthood, whereas nonviolent delinquency and substance use increased in adolescence before decreasing in the transition to adulthood. Maltreatment reduced sensitivity to parental closeness and friendship involvement, although patterns varied based on type of EB outcome. Finally, none of the environmental effects on EB were significantly moderated by the dopamine polygenic risk score after accounting for multiple testing. These findings underline the enduring effects of early maltreatment and implicate that maltreatment may contribute to long-term risk for EB by influencing children's sensitivity to social relationship factors in adolescence.

Relationship Between Childhood Maltreatment and Early Adult Substance Use

2009 ◽  
Author(s):  
Laura Elwyn ◽  
Carolyn A. Smith ◽  
Timothy O. Ireland
Keyword(s):  
Substance Use ◽  
Childhood Maltreatment

Polygenic Scores Predict the Development of Alcohol and Nicotine Use Problems from Adolescence through Young Adulthood

2020 ◽  
Author(s):  
Joseph D. Deak ◽  
D. Angus Clark ◽  
Mengzhen Liu ◽  
C. Emily Durbin ◽  
William G. Iacono ◽  
...  
Keyword(s):  
Substance Use ◽  
Alcohol Use ◽  
Young Adulthood ◽  
Externalizing Behavior ◽  
Molecular Genetic ◽  
Early Adulthood ◽  
Predictive Utility ◽  
Problematic Use ◽  
Discovery Sample ◽  
Polygenic Scores

Objective: Molecular genetic studies of alcohol and nicotine have identified many genome-wide loci. We examined the predictive utility of drinking and smoking polygenic scores (PGS) for alcohol and nicotine use from late childhood to early adulthood, substance-specific versus broader-liability PGS effects, and if PGS performance varied between consumption versus pathological use. Methods: Latent growth curve models with structured residuals were used to assess the predictive utility of drinks per week and regular smoking PGS for measures of alcohol and nicotine consumption and problematic use from age 14 to 34. PGSs were generated from the largest discovery sample for alcohol and nicotine use to date (i.e., GSCAN), and examined for associations with alcohol and nicotine use in the Minnesota Twin Family Study (N=3225).Results: The drinking PGS was a significant predictor of age 14 problematic alcohol use and increases in problematic use during young adulthood. The smoking PGS was a significant predictor for all nicotine use outcomes. After adjusting for the effects of both PGSs, the smoking PGS demonstrated incremental predictive utility for most alcohol use outcomes and remained a significant predictor of nicotine use trajectories. Conclusions: Higher PGS for drinking and smoking were associated with more problematic levels of substance use longitudinally. The smoking PGS seems to capture both nicotine-specific and non-specific genetic liability for substance use, and may index genetic risk for broader externalizing behavior. Validation of PGS within longitudinal designs may have important clinical implications should future studies support the clinical utility of PGS for substance use disorders.

Socialization processes within adolescents’ relationships with parents and peers predicting couples’ intimate partner violence in adulthood: A social learning perspective

2021 ◽  
pp. 1-14
Author(s):  
Thao Ha ◽  
Mark J. Van Ryzin ◽  
Kit K. Elam
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Partner Violence ◽  
Violent Behavior ◽  
Early Adulthood ◽  
Intimate Partner ◽  
High Risk Sexual Behavior ◽  
Self Reports ◽  
Socialization Processes ◽  
Risk Sexual Behavior

Abstract Previous studies have established that individual characteristics such as violent behavior, substance use, and high-risk sexual behavior, as well as negative relationships with parents and friends, are all risk factors for intimate partner violence (IPV). In this longitudinal prospective study, we investigated whether violent behavior, substance use, and high-risk sexual behavior in early adulthood (ages 22–23 years) mediated the link between family conflict and coercive relationship talk with friends in adolescence (ages 16–17 years) and dyadic IPV in adulthood (ages 28–30 years). A total of 998 individuals participated in multimethod assessments, including observations of interactions with parents and friends. Data from multiple reporters were used for variables of interest including court records, parental and self-reports of violence, self-reports of high-sexual-risk behaviors and substance use, and self- and romantic partner-reports of IPV. Longitudinal mediation analyses showed that violent behavior during early adulthood mediated the link between coercive relationship talk with friends in adolescence and dyadic IPV in adulthood. No other mediation paths were found and there was no evidence of gender differences. Results are discussed with attention to the interpersonal socialization processes by which IPV emerges relative to individual risk factors.

Substance Use and Peers During Adolescence and the Transition to Adulthood

2014 ◽  
Author(s):  
Megan E. Patrick ◽  
John E. Schulenberg ◽  
Jennifer Maggs ◽  
Julie Maslowsky
Keyword(s):  
Substance Use ◽  
Peer Relationships ◽  
Social Relationships ◽  
Transition To Adulthood ◽  
Peer Relations ◽  
Peer Groups ◽  
Social Contexts ◽  
Cigarette Use ◽  
Developmental Transitions ◽  
Wide Range

This chapter summarizes recent literature concerning the connection between peers and substance use (i.e., alcohol use, cigarette use, and illicit drug use) during adolescence and the transition to adulthood. The broad category of peers consists of a wide range of social relationships including best friends, peer groups, and crowds; important aspects include peer activities, relationships, and influence. Young people both select their friends (e.g., based on shared interests) and are influenced, or socialized, by their selected peers. When examining the dynamic periods of life that cover the transitions into, through, and out of adolescence and into the post-high school years, selection and socialization are especially important, given that many transitions involve changes in social contexts and peer relationships. The authors take a developmental perspective by focusing on the developmental transitions that occur during adolescence and the transition to adulthood and how they influence peer relations and substance use.

scholarly journals Cumulative Inequality at the End of Life?: Racial Disparities in Impairment in the Time Before Death

2018 ◽  
Vol 75 (6) ◽  
pp. 1292-1301 ◽  
Author(s):  
Miles G Taylor ◽  
Stella N Min ◽  
Keshia M Reid
Keyword(s):  
Racial Disparities ◽  
Growth Curves ◽  
The Elderly ◽  
Functional Independence ◽  
Epidemiologic Studies ◽  
Future Research ◽  
Racial Inequalities ◽  
Latent Growth Curves ◽  
The North ◽  
Cumulative Inequality

Abstract Objectives Drawing from cumulative inequality (CI) theory, the current study examined racial disparities in impairment as individuals approached death to determine whether proposed mechanisms hypothesized to fuel or diminish racial disparities at late ages were at work at the end of individualized life spans. Method Black–white disparities were analyzed among decedents using latent growth curves based on the data from the North Carolina Established Populations for Epidemiologic Studies of the Elderly (EPESE) (N = 1,926). Results Consistent with previous literature, racial inequalities in functional disparities diminish at late ages. However, significant black–white disparities emerge as older adults approach death, exponentially increasing within the 2 years immediately preceding death. Further, these disparities are not fully mediated by socioeconomic status. Discussion The results confirm that CI in health outcomes is observable in late life among individual life spans, suggesting the years surrounding death may be a particularly vulnerable period for health inequality. Future research should examine how advantaged statuses translate to increased access to health-related resources that aid in maintaining greater functional independence until the last stage of life.

scholarly journals Childhood Maltreatment Predicts Poor Economic and Educational Outcomes in the Transition to Adulthood

2018 ◽  
Vol 108 (9) ◽  
pp. 1142-1147 ◽  
Author(s):  
Sara R. Jaffee ◽  
Antony Ambler ◽  
Melissa Merrick ◽  
Sidra Goldman-Mellor ◽  
Candice L. Odgers ◽  
...  
Keyword(s):  
Transition To Adulthood ◽  
Childhood Maltreatment ◽  
Educational Outcomes

scholarly journals Polygenic Scores Predict the Development of Alcohol and Nicotine Use Problems from Adolescence through Young Adulthood

2020 ◽  
Author(s):  
Joseph D. Deak ◽  
D. Angus Clark ◽  
Mengzhen Liu ◽  
C. Emily Durbin ◽  
William G. Iacono ◽  
...  
Keyword(s):  
Substance Use ◽  
Alcohol Use ◽  
Young Adulthood ◽  
Externalizing Behavior ◽  
Molecular Genetic ◽  
Early Adulthood ◽  
Predictive Utility ◽  
Problematic Use ◽  
Discovery Sample ◽  
Polygenic Scores

AbstractObjectiveMolecular genetic studies of alcohol and nicotine have identified many genome-wide loci. We examined the predictive utility of drinking and smoking polygenic scores (PGS) for alcohol and nicotine use from late childhood to early adulthood, substance-specific versus broader-liability PGS effects, and if PGS performance varied between consumption versus pathological use.MethodsLatent growth curve models with structured residuals were used to assess the predictive utility of drinks per week and regular smoking PGS for measures of alcohol and nicotine consumption and problematic use from age 14 to 34. PGSs were generated from the largest discovery sample for alcohol and nicotine use to date (i.e., GSCAN), and examined for associations with alcohol and nicotine use in the Minnesota Twin Family Study (N=3225).ResultsThe drinking PGS was a significant predictor of age 14 problematic alcohol use and increases in problematic use during young adulthood. The smoking PGS was a significant predictor for all nicotine use outcomes. After adjusting for the effects of both PGSs, the smoking PGS demonstrated incremental predictive utility for most alcohol use outcomes and remained a significant predictor of nicotine use trajectories.ConclusionsHigher PGS for drinking and smoking were associated with more problematic levels of substance use longitudinally. The smoking PGS seems to capture both nicotine-specific and non-specific genetic liability for substance use, and may index genetic risk for broader externalizing behavior. Validation of PGS within longitudinal designs may have important clinical implications should future studies support the clinical utility of PGS for substance use disorders.

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