Manuka honey mouthwash does not affect oral mucositis in head and neck cancer patients in New Zealand

2011 ◽  
Vol 11 (4) ◽  
pp. 249-256 ◽  
Author(s):  
Emma Parsons ◽  
Aubrey Begley ◽  
Patries Herst
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
New Zealand ◽  
Head And Neck ◽  
Oral Mucositis ◽  
Standard Care ◽  
Manuka Honey ◽  
Patient Health ◽  
Radiation Induced

AbstractOral mucositis is an unavoidable side effect of radiation therapy to the head and neck, which can compromise patient health and quality of life. This study investigates the effect of manuka honey on the extent of oral mucositis in head and neck patients in New Zealand. A total of 28 patients were recruited; 10 patients received standard care and 18 patients were given additional manuka honey. Honey was used three times a day; assessment included: extent of oral mucositis using a multi-site mucositis scoring system, weight and quality of life. The first six patients, randomised to the honey arm, used undiluted honey and pulled out in the first week because of extreme nausea, vomiting and stinging sensations in the mouth. The next 12 honey patients used a honey mouthwash (diluted 1:3). Six of these patients completed the trial and four more completed the first 4 weeks of the trial. Eight control patients completed the trial. In contrast to previous honey trials in Malaysia, Egypt, Iran and India, diluted manuka honey did not decrease the extent and onset of radiation-induced oral mucositis but did appear to ameliorate radiation-induced weight loss and increase quality of life in the absence of cisplatin chemotherapy.

Do grape and black mulberry molasses have an effect on oral mucositis and quality of life in patients with head and neck cancer?

2021 ◽  
Author(s):  
Sezin Yuce Sari ◽  
Caglayan Selenge Beduk Esen ◽  
Gozde Yazici ◽  
Deniz Yuce ◽  
Mustafa Cengiz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis

Quality of life as predictor of weight loss in patients with head and neck cancer

Head & Neck ◽  
2005 ◽  
Vol 27 (4) ◽  
pp. 302-310 ◽  
Author(s):  
Karin M. Petruson ◽  
Ewa M. Silander ◽  
Eva B. Hammerlid
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer

Radiation-induced Xerostomia in patients with head and neck cancer: Pathogenesis, impact on quality of life, and management

Head & Neck ◽  
2004 ◽  
Vol 26 (9) ◽  
pp. 796-807 ◽  
Author(s):  
Mark S. Chambers ◽  
Adam S. Garden ◽  
Merrill S. Kies ◽  
Jack W. Martin
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Cancer Pathogenesis ◽  
Radiation Induced

scholarly journals A Study to Assess the Quality of Life of Postoperative Patients With Oral Cancer in B.R.A I.R.C.H., AIIMS, New Delhi

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 100s-100s
Author(s):  
N. Paulose ◽  
A. Sinha ◽  
S.V.S. Deo
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Oral Cancer ◽  
Hospital Stay ◽  
Head And Neck ◽  
New Delhi ◽  
The World ◽  
Speech Problem

Introduction: Cancer is a leading cause of death in both developed and underdeveloped countries in the world. The Indian subcontinent accounts for one-third of the world burden of head and neck cancer. Surgery is the standard treatment of choice for head and neck cancers. It is imperative to give supportive care to improve the quality of life. Aim: To assess the quality of life of postoperative patients with oral cancer in B.R.A I.R.C.H, AIIMS, New Delhi. Methodology: The study was conducted at B.R.A.I.R.C.H, AIIMS, New Delhi. The data were collected by convenience sampling from 50 adults who underwent surgery for oral during June 2017 to December 2017. Standardized self-structured EORTC QOL(H&N) was used to assess the perceived level of the quality of life of postoperative patients with oral cancer during hospital stay and at one month follow-up. Ethical clearance was obtained from institutional ethics committee. Results: 80% patients were male. Majority of the patients underwent mandibulectomy (66%) modified neck dissection (60%) and regional flap reconstruction (56%). The major symptoms perceived during hospital stay were pain (98%), speech problem (84%), problem in opening mouth (82%), felt ill (80%), weight loss (74%), etc. and at one month follow-up were problem in opening mouth (90.6%), pain (90.5%), speech problem (83.6%), weight loss (82%), among many others. There was a significant decrease in the perceived pain (11.2 ± 2.99) at one month follow-up (9.12 ± 3.42). Conclusion: Most of the patients experience pain, problem in opening mouth, sticky saliva, speech problem, trouble in social contact, weight loss, etc.

Radiation Induced Xerostomia: Current Concepts and Future Trends

2017 ◽  
Vol 2 (3) ◽  
pp. 256 ◽  
Author(s):  
Manu Krishnan ◽  
Satish R Iyer ◽  
Kanti Lal Chakraborti ◽  
Saraswathy Seema ◽  
Tarun Sekhri
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Salivary Gland ◽  
Head And Neck ◽  
Neck Cancer ◽  
Current Knowledge ◽  
Intensity Modulated Radiotherapy ◽  
Chemical Derivatives ◽  
Radiation Induced

Radiation induced xerostomia is a persistent clinical presentation that affects the quality of life in head and neck cancer patients even with the best of the intensity modulated radiotherapy protocols. Comprehensive review of the anatomic, histologic, developmental and neuronal entities of salivary glands from a regenerative perspective, ensuing radiation is taken. It also evaluates the systemic and glandular radiation responses that form the early and late clinical changes. From these, the article submits probable strategies; based on the current knowledge and future challenges involved, in reversing radiation induced xerostomia. Further, it elaborates on the status of radioprotectors and mitigators including the recently reported biologic and chemical derivatives and proposes the rationale of using combination radioprotector therapy in radiation injuries. A brief of palliative regimes, alternate treatment modes and technologic advancements in radiotherapy are also explained. Salivary gland histologic components, which need to be protected in the emerging radiotherapy protocols and can be targeted in different salivary gland regeneration therapies is highlighted. The paper contributes to an improved understanding in radiation induced xerostomia and deliberates on novel mechanisms towards enhancing quality of life in head and neck cancer radiotherapy patients.

Impact of Late Treatment-Related Toxicity on Quality of Life Among Patients With Head and Neck Cancer Treated With Radiotherapy

2008 ◽  
Vol 26 (22) ◽  
pp. 3770-3776 ◽  
Author(s):  
Johannes A. Langendijk ◽  
Patricia Doornaert ◽  
Irma M. Verdonck-de Leeuw ◽  
Charles R. Leemans ◽  
Neil K. Aaronson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck ◽  
Radiation Therapy Oncology Group ◽  
Life Questionnaire ◽  
Related Quality ◽  
Health Related ◽  
Late Treatment ◽  
Radiation Induced ◽  
The Impact

Purpose To investigate the impact of treatment-related toxicity on health-related quality of life (HRQoL) among patients with head and neck squamous cell carcinoma treated with radiotherapy either alone or in combination with chemotherapy or surgery. Patients and Methods The study sample was composed of 425 disease-free patients. Toxicity was scored according to the European Organisation for Research and Treatment of Cancer (EORTC)/Radiation Therapy Oncology Group (RTOG) late radiation-induced morbidity scoring system. HRQoL was assessed using the EORTC Quality of Life Questionnaire C30. These assessments took place at 6, 12, 18, and 24 months after completion of radiotherapy. The analysis was performed using a multivariate analysis of variance. Results Of the six RTOG scales investigated, two significantly affected self-reported HRQoL, salivary gland (RTOGxerostomia) and esophagus/pharynx (RTOGswallowing). Although RTOGxerostomia was reported most frequently, HRQoL was most affected by RTOGswallowing, particularly in the first 18 months after completion of radiotherapy. Conclusion Late radiation-induced toxicity, particularly RTOGswallowing and RTOGxerostomia, has a significant impact on the more general dimensions of HRQoL. These findings suggest that the development of new radiation-induced delivery techniques should not only focus on reduction of the dose to the salivary glands, but also on anatomic structures that are involved in swallowing.

PP074-SUN WEIGHT LOSS DUE TO RADIOTHERAPY IS ASSOCIATED WITH A DETERIORATION IN QUALITY OF LIFE IN HEAD AND NECK CANCER PATIENTS

2011 ◽  
Vol 6 (1) ◽  
pp. 51-52
Author(s):  
J.A.E. Langius ◽  
A.M. van Dijk ◽  
P. Doornaert ◽  
H.M. Kruizenga ◽  
I.M. Verdonck-de Leeuw ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer
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