scholarly journals The use of second generation antipsychotics for post-traumatic stress disorder in a US Veterans Health Administration Medical Center

2013 ◽  
Vol 23 (3) ◽  
pp. 281-288 ◽  
Author(s):  
E. Hermes ◽  
M. Sernyak ◽  
R. Rosenheck

Background.Prior studies of antipsychotic use in individuals with post-traumatic stress disorder (PTSD) are limited because administrative data lacks information on why providers choose particular medications.Methods.This study examined 2613 provider surveys completed at the time any second generation antipsychotic (SGA) was prescribed over a 20-month period at a single Veterans Affairs medical center. Clinical correlates and reasons for SGA selection among individuals with PTSD compared to those with other psychiatric disorders were identified using chi-square.Results.PTSD was the sole diagnosis in n = 339 (13%) and one of several psychiatric diagnoses in n = 236 (9%) surveys. ‘Efficacy’ was the most common reason given for the prescriptions of SGAs in all surveys (51%) and among individuals with PTSD (46%). ‘Sleep/sedation’ was the only reason cited, significantly more frequently among those with PTSD (39% with PTSD only, 35% with PTSD plus another diagnosis, and 31% without PTSD [χ2 = 12.86, p < 0.0016)]. The proportion identifying ‘efficacy’ as a reason for SGA use was smaller in patients with PTSD (44% with PTSD only, 49% with PTSD and another diagnosis, and 53% without PTSD [χ2 = 8.78, p < 0.0125)]. Quetiapine was the most frequently prescribed SGA in the entire sample and among veterans with PTSD (47%).Conclusions.Clinician use of SGAs is often driven by efficacy, for which there is limited evidence, and distinctly driven by the goal of sedation among patients with PTSD.


2017 ◽  
Vol 16 (1) ◽  
pp. 37-44 ◽  
Author(s):  
Megan Kelly ◽  
Shihwe Wang ◽  
Robert Rosenheck

Purpose Veterans with post-traumatic stress disorder (PTSD) have high lifetime rates of smoking and often have substantial difficulty quitting. However, relatively little research has focussed on the use of Veterans Health Administration (VHA) intensive tobacco cessation counseling services by veterans with PTSD and the characteristics of veterans with PTSD who do and do not use these services. The paper aims to discuss these issues. Design/methodology/approach The present study is an analysis of national VHA administrative data fiscal year 2012 that identified utilization rates of VHA intensive tobacco cessation counseling among veterans with diagnoses of both PTSD and tobacco use disorder (TUD) (N=144,990) and the correlates of tobacco cessation counseling use. Findings Altogether, 7,921 veterans with PTSD diagnosed with TUD used VHA tobacco cessation services (5.5 percent). Veterans with PTSD who used tobacco cessation counseling services were more likely to have been homeless, to have a comorbid drug use disorder, and had used other VHA services more frequently than their counterparts who did not access tobacco cessation counseling. The use of outpatient mental health and substance use services was the strongest correlate of tobacco cessation counseling use by veterans in this sample. Notably, veterans with PTSD, TUD and HIV were more likely to engage in tobacco cessation services. Originality/value This study demonstrates that future efforts should focus on increasing provider and veteran awareness of and accessibility to VHA intensive tobacco cessation counseling for veterans with PTSD.



2016 ◽  
Vol 5 (12) ◽  
pp. 117 ◽  
Author(s):  
Mark Detweiler ◽  
Bhuvaneshwar Pagadala ◽  
Joseph Candelario ◽  
Jennifer Boyle ◽  
Jonna Detweiler ◽  
...  


1994 ◽  
Vol 7 (2) ◽  
pp. 217-235 ◽  
Author(s):  
David Read Johnson ◽  
Susan C. Feldman ◽  
Steven M. Southwick ◽  
Dennis S. Charney


CNS Spectrums ◽  
2012 ◽  
Vol 17 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Robert N. McLay ◽  
Jennifer Webb-Murphy ◽  
Paul Hammer ◽  
Stacy Volkert ◽  
Warren Klam

IntroductionRisk for post-traumatic stress disorder (PTSD) varies in part due to the nature of the traumatic event involved. Both injury and return from combat pose high risk of PTSD symptoms. How different injuries may predispose towards PTSD is less well understood.MethodsA retrospective record review was conducted from 1402 service members who had returned to Naval Medical Center San Diego from Iraq or Afghanistan and who had completed the PTSD Checklist as part of their post-deployment screening. Rates of PTSD were examined in relation to mechanism of injury.ResultsOf those without injury, 8% met Diagnostic and Statistical Manual criteria for PTSD. Thirteen percent of those with a penetrating injury, 29% with blunt trauma, and 33% with combination injuries met criteria for PTSD. PTSD severity scores varied significantly according to type of injury.DiscussionThe World War I concept of “shell shock” implied that blast-related injuries were more likely to result in psychological symptoms than were other injuries. These data may support that idea. Circumstance of injury, population differences, and reporting bias could also have influenced the results.ConclusionThese results suggest that service members with blunt or combination injuries merit particular attention when screening for PTSD.



Sari Pediatri ◽  
2016 ◽  
Vol 17 (6) ◽  
pp. 441
Author(s):  
Putu Dian Savitri Irawan ◽  
Soetjiningsih Soetjiningsih ◽  
IGA Trisna Windiani ◽  
I Gst Ag Sugitha Adnyana ◽  
IGA Endah Ardjana

Latar belakang. Stres pascatrauma (post traumatic stress disorder atau PTSD) merupakan suatu gangguan psikiatri fungsi sosial seseorang.Universitas California Los Angeles (UCLA) mengembangkan serangkaian self-report kuesioner yang disebut PTSD Reaction Index(PTSD-RI) untuk deteksi dini gangguan tersebut. Namun, kuesioner tersebut belum pernah digunakan di Indonesia.Tujuan. Mengetahui reliabilitas instrumen post traumatic stress disoder reaction index (PTSD-RI) versi remaja, prevalensi, serta faktoryang berhubungan dengan PTSD.Metode. Penelitian potong lintang dilaksanakan di enam SMUN di Denpasar. Digunakan kuesioner PTSD-RI versi remaja yangtelah diterjemahkan ke dalam Bahasa Indonesia. Digunakan uji α Cronbach untuk menilai reliabilitas PTSD-RI. Analisis statistikmenggunakan uji chi-square dan multivariat regresi logistik.Hasil. Terdapat 300 pelajar SMUN yang mengikuti penelitian. Enam puluh orang (20%) dengan tersangka PTSD. ReliabilitasPTSD-RI baik (koefisien α 0,94). Tipe kepribadian tertutup sebagai faktor risiko PTSD [RP 3,55 (IK95% 1,46-8,66), p=0,01].Keluarga yang harmonis [RP 0,35 (IK95% 0,08-0,78), p=0,02], adanya dukungan keluarga [RP 0,13 (IK95% 0,03-0,50), p=0,01],adanya dukungan sosial [RP 0,25 (IK95% 0,09-0,68), p=0,01], serta trauma tunggal [RP 0,02 (IK95% 0,14- 0,82), p=0,01] berperansebagai faktor protektif PTSD.Kesimpulan. Instrumen PTSD-RI memiliki reliabilitas yang baik sehingga dapat digunakan di Indonesia. Prevalensi PTSD padaremaja di Denpasar sebesar 20%.



2012 ◽  
Vol 56 (2) ◽  
pp. 169-177 ◽  
Author(s):  
Amnon Raviv

In recent years medical clowning has been an effective tool used in the treatment of people suffering from acute and post-traumatic stress disorder in war zones and in the wake of natural disasters. Clown Doctors in the Barzilai Medical Center in southern Israel, near the Gaza border, encounter ASD/PTSD patients from both sides of the conflict.



Healthcare ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 373 ◽  
Author(s):  
Min Cheol Chang ◽  
Donghwi Park

Background: The coronavirus disease (COVID-19) emerged from China and rapidly spread to many other countries. In this study, we investigated the prevalence of post-traumatic stress disorder (PTSD) among patients with COVID-19 who were treated and discharged from a university hospital in Daegu, Korea. Methods: In total, 64 patients who were diagnosed with COVID-19 and then hospitalized, treated and discharged from the university hospital between February and April 2020 participated in our study. We conducted telephone interviews with the participants and evaluated the presence of PTSD using the Post-Traumatic Stress Disorder Checklist-5 (PCL-5) based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-5; score range: 0–80). If a score of ≥33 was obtained, then a diagnosis of PTSD was made. We analyzed the association between PTSD and demographic and clinical characteristics using the Mann–Whitney U and chi-square tests. Results: In total, 13 patients had a PCL-5 score of ≥33, which indicated that 20.3% (n = 64) of the patients had PTSD. No significant differences were observed in demographic characteristics, including, sex, age, hospitalization time and duration after discharge, between patients with PTSD and those without PTSD. Conclusions: The prevalence rate of PTSD was 20.3% in patients with COVID-19 who had been hospitalized, treated and discharged. Accordingly, clinicians should be aware of the high possibility of PTSD among COVID-19 patients. Mental health interventions supporting the mental health of patients should be provided to affected patients.



BJPsych Open ◽  
2016 ◽  
Vol 2 (5) ◽  
pp. 286-293 ◽  
Author(s):  
Ilan Harpaz-Rotem ◽  
Robert Rosenheck ◽  
Somaia Mohamed ◽  
Robert Pietrzak ◽  
Rani Hoff

BackgroundThe pharmacological treatment of post-traumatic stress disorder (PTSD) is extremely challenging, as no specific agent has been developed exclusively to treat this disorder. Thus, there are growing concerns among the public, providers and consumers associated with its use as the efficacy of some agents is still in question.AimsWe applied a dimensional and symptom cluster-based approach to better understand how the heterogeneous phenotypic presentation of PTSD may relate to the initiation of pharmacotherapy for PTSD initial episode.MethodUS veterans who served in the conflicts in Iraq and Afghanistan and received an initial PTSD diagnosis at the US Veterans Health Administration between 2008 and 2011 were included in this study. Veterans were followed for 365 days from initial PTSD diagnosis to identify initiation for antidepressants, anxiolytics/sedatives/hypnotics, antipsychotics and prazosin. Multivariable analyses were used to assess the relationship between the severity of unique PTSD symptom clusters and receiving prescriptions from each medication class, as well as the time from diagnosis to first prescription.ResultsIncreased severity of emotional numbing symptoms was independently associated with the prescription of antidepressants, and they were prescribed after a substantially shorter period of time than other medications. Anxiolytics/sedatives/hypnotics prescription was associated with heightened re-experiencing symptoms and sleep difficulties. Antipsychotics were associated with elevated re-experiencing and numbing symptoms and prazosin with reported nightmares.ConclusionsPrescribing practices for military-related PTSD appear to follow US VA/DoD clinical guidelines. Results of this study suggest that a novel dimensional and symptom cluster-based approach to classifying the phenotypic presentation of military-related PTSD symptoms may help inform prescribing patterns for PTSD.



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