scholarly journals Direct Analysis of Intact Proteins from Escherichia coli Colonies by Liquid Extraction Surface Analysis Mass Spectrometry

2014 ◽  
Vol 86 (21) ◽  
pp. 10504-10510 ◽  
Author(s):  
Elizabeth C. Randall ◽  
Josephine Bunch ◽  
Helen J. Cooper
Keyword(s):  
Mass Spectrometry ◽  
Escherichia Coli ◽  
Surface Analysis ◽  
Direct Analysis ◽  
Liquid Extraction ◽  
Intact Proteins ◽  
Liquid Extraction Surface Analysis

scholarly journals Potential of Liquid Extraction Surface Analysis Mass Spectrometry (LESA—MS) for the Characterization of Polymer-Based Materials

Polymers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 802 ◽  
Author(s):  
Ambre Issart ◽  
Joanna Szpunar
Keyword(s):  
Mass Spectrometry ◽  
Surface Analysis ◽  
Cost Effective ◽  
Direct Analysis ◽  
Liquid Extraction ◽  
Polymer Science ◽  
Targeted Analysis ◽  
Unknown Species ◽  
Liquid Extraction Surface Analysis ◽  
Efficient Extraction

Liquid extraction surface analysis mass spectrometry (LESA -MS) is a direct analysis method suitable for the analysis of polymers. It is based on a fast and efficient extraction of polymer components, such as non-intentionally added species (NIAS), post-polymerization residues, or additives, and residues resulting from specific uses followed by their MS detection. In comparison with batch methods, it is a “green” method, using negligible volumes of organic solvents, and it is cost-effective, avoiding lengthy sample preparation procedures. It can be used for the detection of known molecules (targeted analysis), identification of unknown species (exploratory analysis requiring MS/MS) and semi-quantative analysis, if standards are available. The to-date applications of LESA-MS in the field of polymer science are reviewed and critically discussed taking into account the hands-on experience from the authors’ laboratory. Future possibilities of LESA applications are highlighted.

scholarly journals Improved Extraction Repeatability and Spectral Reproducibility for Liquid Extraction Surface Analysis–Mass Spectrometry Using Superhydrophobic–Superhydrophilic Patterning

2018 ◽  
Vol 90 (10) ◽  
pp. 6001-6005 ◽  
Author(s):  
Joris Meurs ◽  
Morgan R. Alexander ◽  
Pavel A. Levkin ◽  
Simon Widmaier ◽  
Josephine Bunch ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Surface Analysis ◽  
Liquid Extraction ◽  
Liquid Extraction Surface Analysis

Mapping Drug Distribution in Brain Tissue Using Liquid Extraction Surface Analysis Mass Spectrometry Imaging

2015 ◽  
Vol 87 (19) ◽  
pp. 10146-10152 ◽  
Author(s):  
John G. Swales ◽  
James W. Tucker ◽  
Michael J. Spreadborough ◽  
Suzanne L. Iverson ◽  
Malcolm R. Clench ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Brain Tissue ◽  
Surface Analysis ◽  
Mass Spectrometry Imaging ◽  
Drug Distribution ◽  
Liquid Extraction ◽  
Liquid Extraction Surface Analysis
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