In Vivo Monitoring of Oxygen in Rat Brain by Carbon Fiber Microelectrode Modified with Antifouling Nanoporous Membrane

2019 ◽  
Vol 91 (5) ◽  
pp. 3645-3651 ◽  
Author(s):  
Lin Zhou ◽  
Hanfeng Hou ◽  
Huan Wei ◽  
Lina Yao ◽  
Lei Sun ◽  
...  
2019 ◽  
Vol 91 (16) ◽  
pp. 10786-10791 ◽  
Author(s):  
Taotao Feng ◽  
Wenliang Ji ◽  
Qiao Tang ◽  
Huan Wei ◽  
Shuai Zhang ◽  
...  

The Analyst ◽  
2015 ◽  
Vol 140 (21) ◽  
pp. 7154-7159 ◽  
Author(s):  
Peipei Zhong ◽  
Ping Yu ◽  
Kai Wang ◽  
Jie Hao ◽  
Junjie Fei ◽  
...  

A ferricyanide-backfilled cylindrical carbon fiber microelectrode of high stability and low polarized potential was fabricated and used for in vivo analysis.


2007 ◽  
Vol 79 (17) ◽  
pp. 6559-6565 ◽  
Author(s):  
Meining Zhang ◽  
Kun Liu ◽  
Ling Xiang ◽  
Yuqing Lin ◽  
Lei Su ◽  
...  

2012 ◽  
Vol 107 (6) ◽  
pp. 1731-1737 ◽  
Author(s):  
Natalie R. Herr ◽  
Jinwoo Park ◽  
Zoé A. McElligott ◽  
Anna M. Belle ◽  
Regina M. Carelli ◽  
...  

Norepinephrine (NE) is an easily oxidized neurotransmitter that is found throughout the brain. Considerable evidence suggests that it plays an important role in neurocircuitry related to fear and anxiety responses. In certain subregions of the bed nucleus of the stria terminalis (BNST), NE is found in large amounts. In this work we probed differences in electrically evoked release of NE and its regulation by the norepinephrine transporter (NET) and the α2-adrenergic autoreceptor (α2-AR) in two regions of the BNST of anesthetized rats. NE was monitored in the dorsomedial BNST (dmBNST) and ventral BNST (vBNST) by fast-scan cyclic voltammetry at carbon fiber microelectrodes. Pharmacological agents were introduced either by systemic application (intraperitoneal injection) or by local application (iontophoresis). The iontophoresis barrels were attached to a carbon fiber microelectrode to allow simultaneous detection of evoked NE release and quantitation of iontophoretic delivery. Desipramine (DMI), an inhibitor of NET, increased evoked release and slowed clearance of released NE in both regions independent of the mode of delivery. However, the effects of DMI were more robust in the vBNST than in the dmBNST. Similarly, the α2-AR autoreceptor inhibitor idazoxan (IDA) enhanced NE release in both regions but to a greater extent in the vBNST by both modes of delivery. Since both local application by iontophoresis and systemic application of IDA had similar effects on NE release, our results indicate that terminal autoreceptors play a predominant role in the inhibition of subsequent release.


The Analyst ◽  
2017 ◽  
Vol 142 (9) ◽  
pp. 1452-1458 ◽  
Author(s):  
Li Liu ◽  
Limin Zhang ◽  
Zhihui Dai ◽  
Yang Tian

A simple ratiometric electrochemical biosensor for NO monitoring in rat brain following cerebral ischemia was developed based on a carbon nanotube fiber modified with hemin.


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