We designed and investigated novel mitochondria-targeting heavy-atom-free BODIPY photosensitizers (R-BODs) that possessed considerable singlet oxygen generation abilities and good fluorescence properties for imaging-guided photodynamic therapy (PDT).
A water soluble donor–acceptor–donor structure with mitochondria-targeting capability exhibits high singlet oxygen generation efficacy for efficient low-energy photodynamic therapy.
Photodynamic therapy (PDT) is a promising strategy in cancer treatment with its relatively lower side effect profile. Undoubtedly, the key component of PDT is the photosensitizers with a high ability...
Photodynamic therapy (PDT) is a promising method for cancer therapy and also may initiate unexpected damages to normal cells and tissues. Herein, we developed a near-infrared (NIR) light-activatable nanophotosensitizer, which...
Correction for ‘Efficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy’ by Shigenobu Yano et al., Chem. Commun., 2015, DOI: 10.1039/c5cc07353g.
We report a new way to engineer nanomaterials from biomolecules (N-dots) with bright fluorescence and high singlet oxygen generation towards theranostic applications.
Mitochondria-targeted photosensitizers with highly efficient singlet oxygen generation, bright near-infrared AIE and good two-photon absorption are obtained through ingenious molecular engineering for cancer cell-selective photodynamic therapy.
Fine-tuning the electronic structure of heavy-atom-free BODIPY photosensitizers for fluorescence imaging and mitochondria-targeted photodynamic therapy
