Characterizations and the Mechanism Underlying Osteogenic Activity of Peptides from Enzymatic Hydrolysates of Stichopus japonicus

Author(s):  
Meilian Yang ◽  
Zhe Xu ◽  
Di Wu ◽  
Yu Dong ◽  
Zhenyu Wang ◽  
...  
2019 ◽  
Vol 10 (12) ◽  
pp. 7745-7754 ◽  
Author(s):  
Zhe Xu ◽  
Fujunzhu Zhao ◽  
Hui Chen ◽  
Shiqi Xu ◽  
Fengjiao Fan ◽  
...  

Seafood provides a range of health benefits due to its nutritional and bioactive components. The proteins and peptides from Mytilus edulis have good bone growth promoting activities.


Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
EK Kim ◽  
SJ Lee ◽  
JW Hwang ◽  
PJ Park

2014 ◽  
Author(s):  
Julie Leotot ◽  
Angelique Lebouvier ◽  
Philippe Hernigou ◽  
Helene Rouard ◽  
Nathalie Chevallier

Metals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 781
Author(s):  
Weiyan Jiang ◽  
Wenzhou Yu

A gradient Mg-8 wt % Si alloy, which was composed of the agglomerated Mg2Si crystals coating (GMS8-1) and the eutectic Mg–Si alloy matrix (GMS8-2), was designed for biodegradable orthopedic implant materials. The bio-corrosion behavior was evaluated by the electrochemical measurements and the immersion tests. The results show that a significant improvement of bio-corrosion resistance was achieved by using the gradient Mg–Si alloy, as compared with the traditional Mg-8 wt % Si alloy (MS8), which should be attributed to the compact and insoluble Mg2Si phase distributed on the surface of the material. Especially, GMS8-1 exhibits the highest polarization resistance of 1610 Ω, the lowest corrosion current density of 1.7 × 10−6 A.cm−2, and the slowest corrosion rate of 0.10 mm/year. In addition, GMS8-1 and GMS8-2 show better osteogenic activity than MS8, with no cytotoxicity to MC3T3-E1 cells. This work provides a new way to design a gradient biodegradable Mg alloys with some certain biological functions.


Sign in / Sign up

Export Citation Format

Share Document