Singlet Oxygen Generation from a Water-Soluble Hypervalent Iodine(V) Reagent AIBX and H2O2: An Access to Artemisinin

Author(s):  
Hui-Jie Shen ◽  
Ze-Nan Hu ◽  
Chi Zhang
2020 ◽  
Vol 52 (12) ◽  
pp. 1387-1394
Author(s):  
Thi Lien Nguyen ◽  
Risa Katayama ◽  
Chie Kojima ◽  
Akikazu Matsumoto ◽  
Kazuhiko Ishihara ◽  
...  

Carbon ◽  
2004 ◽  
Vol 42 (5-6) ◽  
pp. 1195-1198 ◽  
Author(s):  
Bertrand Vileno ◽  
Andrzej Sienkiewicz ◽  
Małgorzata Lekka ◽  
Andrzej J. Kulik ◽  
László Forró

2006 ◽  
Vol 43 (12) ◽  
pp. 1955-1963 ◽  
Author(s):  
Grace So ◽  
Aliaksandr Karotki ◽  
Sarika Verma ◽  
Kenneth Pritzker ◽  
Brian Wilson ◽  
...  

2013 ◽  
Vol 17 (01n02) ◽  
pp. 56-62 ◽  
Author(s):  
Kazutaka Hirakawa ◽  
Keito Azumi ◽  
Yoshinobu Nishimura ◽  
Tatsuo Arai ◽  
Yoshio Nosaka ◽  
...  

The effect of the axial ligand fluorination of the water-soluble P(V)porphyrin complex on photosensitized protein damage was examined. The activity of singlet oxygen generation by diethoxyP(V) porphyrin was slightly improved by the fluorination of the ethoxy chains. Absorption spectrum measurements demonstrated the binding interaction between the P(V)porphyrins and human serum albumin, a water-soluble protein. Photo-irradiated P(V)porphyrins damaged the amino acid residue of human serum albumin, resulting in the decrease of the fluorescence intensity from the tryptophan residue of human serum albumin. A singlet oxygen quencher, sodium azide, could not completely inhibit the damage of human serum albumin, suggesting that the electron transfer mechanism contributes to protein damage as does singlet oxygen generation. The decrease of the fluorescence lifetime of P(V)porphyrin by human serum albumin supported the electron transfer mechanism. The estimated contributions of the electron transfer mechanism are 0.57 and 0.44 for the fluorinated and non-fluorinated P(V)porphyrins, respectively. The total quantum yield of the protein photo-oxidation was slightly enhanced by this axial fluorination.


2014 ◽  
Vol 90 (5) ◽  
pp. 997-1003 ◽  
Author(s):  
Alexander S. Stasheuski ◽  
Victor A. Galievsky ◽  
Alexander P. Stupak ◽  
Boris M. Dzhagarov ◽  
Mi Jin Choi ◽  
...  

2006 ◽  
Vol 128 (19) ◽  
pp. 6278-6279 ◽  
Author(s):  
Lixin Shi ◽  
Billy Hernandez ◽  
Matthias Selke

2018 ◽  
Vol 54 (66) ◽  
pp. 9194-9197 ◽  
Author(s):  
Jian Sun ◽  
Xiao Li ◽  
Ke Du ◽  
Fude Feng

A water soluble donor–acceptor–donor structure with mitochondria-targeting capability exhibits high singlet oxygen generation efficacy for efficient low-energy photodynamic therapy.


2021 ◽  
Author(s):  
Esra Tanrıverdi Eçik ◽  
Onur BULUT ◽  
Hasan Hüseyin Kazan ◽  
Elif Şenkuytu ◽  
Bunyemin Cosut

Photodynamic therapy (PDT) is a promising strategy in cancer treatment with its relatively lower side effect profile. Undoubtedly, the key component of PDT is the photosensitizers with a high ability...


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