Singlet oxygen generation by sonication using a water-soluble fullerene (C60) complex: a potential application for sonodynamic therapy

2020 ◽  
Vol 52 (12) ◽  
pp. 1387-1394
Author(s):  
Thi Lien Nguyen ◽  
Risa Katayama ◽  
Chie Kojima ◽  
Akikazu Matsumoto ◽  
Kazuhiko Ishihara ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Potential Application ◽  
Fullerene C60 ◽  
Water Soluble ◽  
Sonodynamic Therapy ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation

scholarly journals Singlet oxygen generation properties of an inclusion complex of cyclic free-base porphyrin dimer and fullerene C60

RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18690-18695 ◽  
Author(s):  
Yousuke Ooyama ◽  
Toshiaki Enoki ◽  
Joji Ohshita ◽  
Takuya Kamimura ◽  
Shuwa Ozako ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
Visible Light ◽  
Singlet Oxygen ◽  
Visible Light Irradiation ◽  
Fullerene C60 ◽  
Light Irradiation ◽  
Free Base ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Porphyrin Dimer

We demonstrate that a cyclic free-base porphyrin dimer and its inclusion complex with fullerene C60 possess the ability to generate singlet oxygen (1O2) under visible light irradiation.

In vitro assay of singlet oxygen generation in the presence of water-soluble derivatives of C60

Carbon ◽  
2004 ◽  
Vol 42 (5-6) ◽  
pp. 1195-1198 ◽  
Author(s):  
Bertrand Vileno ◽  
Andrzej Sienkiewicz ◽  
Małgorzata Lekka ◽  
Andrzej J. Kulik ◽  
László Forró
Keyword(s):  
Singlet Oxygen ◽  
In Vitro Assay ◽  
Water Soluble ◽  
Vitro Assay ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Derivatives Of

Synthesis of porphyrin-incorporated covalent organic frameworks for sonodynamic therapy

2021 ◽  
Author(s):  
Sainan Liu ◽  
Ying Zhou ◽  
Chunling Hu ◽  
Lihan Cai ◽  
Zhendong Liu ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Room Temperature ◽  
Covalent Organic Frameworks ◽  
Sonodynamic Therapy ◽  
Oxygen Generation ◽  
Covalent Organic Framework ◽  
Singlet Oxygen Generation ◽  
Organic Framework

Porphyrin-incorporated covalent organic framework was synthesized at room temperature. The resulting product with uniform morphology and excellent crystallinity exhibited good singlet oxygen generation ability. Both in vitro and in vivo...

scholarly journals Photochemistry of P,N-bidentate rhenium(i) tricarbonyl complexes: reactive species generation and potential application for antibacterial photodynamic therapy

RSC Advances ◽  
2021 ◽  
Vol 11 (51) ◽  
pp. 31959-31966
Author(s):  
Alison Acosta ◽  
Javier Antipán ◽  
Mariano Fernández ◽  
Gaspar Prado ◽  
Catalina Sandoval-Altamirano ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Potential Application ◽  
Reactive Species ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Rhenium Tricarbonyl

Three P,N-rhenium tricarbonyl complexes exhibited photoisomerization upon irradiation at 365 nm, and no CO release was detected. The antibacterial activity is attributed to their singlet oxygen generation, following the same decreasing order: RePNBr > RePNTfO > RePNNBr.

Photosensitized damage of protein by fluorinated diethoxyphosphorus(V)porphyrin

2013 ◽  
Vol 17 (01n02) ◽  
pp. 56-62 ◽  
Author(s):  
Kazutaka Hirakawa ◽  
Keito Azumi ◽  
Yoshinobu Nishimura ◽  
Tatsuo Arai ◽  
Yoshio Nosaka ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Singlet Oxygen ◽  
Human Serum ◽  
Transfer Mechanism ◽  
Water Soluble ◽  
Electron Transfer Mechanism ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation

The effect of the axial ligand fluorination of the water-soluble P(V)porphyrin complex on photosensitized protein damage was examined. The activity of singlet oxygen generation by diethoxyP(V) porphyrin was slightly improved by the fluorination of the ethoxy chains. Absorption spectrum measurements demonstrated the binding interaction between the P(V)porphyrins and human serum albumin, a water-soluble protein. Photo-irradiated P(V)porphyrins damaged the amino acid residue of human serum albumin, resulting in the decrease of the fluorescence intensity from the tryptophan residue of human serum albumin. A singlet oxygen quencher, sodium azide, could not completely inhibit the damage of human serum albumin, suggesting that the electron transfer mechanism contributes to protein damage as does singlet oxygen generation. The decrease of the fluorescence lifetime of P(V)porphyrin by human serum albumin supported the electron transfer mechanism. The estimated contributions of the electron transfer mechanism are 0.57 and 0.44 for the fluorinated and non-fluorinated P(V)porphyrins, respectively. The total quantum yield of the protein photo-oxidation was slightly enhanced by this axial fluorination.

scholarly journals Photophysical Properties and Singlet Oxygen Generation Efficiencies of Water‐Soluble Fullerene Nanoparticles

2014 ◽  
Vol 90 (5) ◽  
pp. 997-1003 ◽  
Author(s):  
Alexander S. Stasheuski ◽  
Victor A. Galievsky ◽  
Alexander P. Stupak ◽  
Boris M. Dzhagarov ◽  
Mi Jin Choi ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Photophysical Properties ◽  
Water Soluble ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Fullerene Nanoparticles
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