Metal-Free Synthesis of N-Aryl-Substituted Azacycles from Cyclic Ethers Using POCl3

2019 ◽  
Vol 84 (11) ◽  
pp. 6689-6696 ◽  
Author(s):  
Minh Thanh La ◽  
Soosung Kang ◽  
Hee-Kwon Kim
Keyword(s):  
Cyclic Ethers ◽  
Metal Free

Metal-Free Regioselective Cross Dehydrogenative Coupling of Cyclic Ethers and Aryl Carbonyls

2019 ◽  
Vol 84 (4) ◽  
pp. 2039-2047 ◽  
Author(s):  
Kishor D. Mane ◽  
Anagh Mukherjee ◽  
Kumar Vanka ◽  
Gurunath Suryavanshi
Keyword(s):  
Cyclic Ethers ◽  
Metal Free ◽  
Dehydrogenative Coupling

Three-Component Ring-Opening Reactions of Cyclic Ethers, α-Diazo Esters, and Weak Nucleophiles under Metal-Free Conditions

2018 ◽  
Vol 83 (23) ◽  
pp. 14385-14395 ◽  
Author(s):  
Lin Lu ◽  
Chuwei Chen ◽  
Huanfeng Jiang ◽  
Biaolin Yin
Keyword(s):  
Ring Opening ◽  
Cyclic Ethers ◽  
Metal Free ◽  
Ring Opening Reactions ◽  
Diazo Esters

Metal-free, radical 1,6-conjugated addition of cyclic ethers with para-quinone methides (p-QMs)

2019 ◽  
Vol 17 (12) ◽  
pp. 3239-3248 ◽  
Author(s):  
Satish G. More ◽  
Gurunath Suryavanshi
Keyword(s):  
Free Radical ◽  
Efficient Method ◽  
Bond Formation ◽  
Cyclic Ethers ◽  
Quinone Methides ◽  
Metal Free

An efficient method for metal-free C–C bond formation between p-quinone methides (p-QMs) and cyclic ethers via a radical pathway to afford substituted diarylmethanes and triarylmethanes or to effect the α-alkylation of the cyclic ethers has been developed.

Metal-Free Decarboxylative Alkoxylation of 2-Picolinic Acid and Its Derivatives with Cyclic Ethers: One Step Construction of C–O and C–Cl Bonds

2018 ◽  
Vol 20 (21) ◽  
pp. 6780-6784 ◽  
Author(s):  
Xiaoqiang Yu ◽  
Min He ◽  
Jianglin Wu ◽  
Chuancheng Zhou ◽  
Xiujuan Feng ◽  
...  
Keyword(s):  
Picolinic Acid ◽  
Cyclic Ethers ◽  
Metal Free ◽  
One Step

scholarly journals Facile Metal-Free Direct Transformation of N-Allyl- and tert-Butyl-Protected Arylamines to Azacycles Using Phosphoryl Chloride and TBD

2020 ◽  
Author(s):  
Van Hieu Tran ◽  
Wan Pyo Hong ◽  
Hee-Kwon Kim
Keyword(s):  
Direct Synthesis ◽  
Practical Approach ◽  
High Yield ◽  
Cyclic Ethers ◽  
Synthetic Approach ◽  
Phosphoryl Chloride ◽  
Direct Transformation ◽  
Metal Free ◽  
Tert Butyl ◽  
Important Contributor

A novel synthetic approach to the preparation of N-aryl substituted azacycles from N-allyl and N-tert-butyl protected arylamines is described. In this preparation, a metal free reagent system utilizing POCl3 and TBD proved to be an important contributor for reactions of N-allyl- and tert-butyl-protected aryamines with cyclic ethers to generate the target azacycles. This protocol provides a practical approach to high yield, direct synthesis of N-aryl substituted five-membered and six-membered azacycles from N-allyl arylamines and N-tert-butyl arylamines

Metal-Free Visible-Light-Promoted C(sp3)–H Functionalization of Aliphatic Cyclic Ethers Using Trace O2

2021 ◽  
Author(s):  
Ben Niu ◽  
Bryan G. Blackburn ◽  
Krishnakumar Sachidanandan ◽  
Maria Victoria Cooke ◽  
Sébastien Laulhé
Keyword(s):  
Visible Light ◽  
Room Temperature ◽  
Cyclic Ethers ◽  
Metal Free ◽  
Bond Forming

Presented is a light-promoted C–C bond forming reaction yielding sulfone and phosphate derivatives at room temperature in the absence of metals or photoredox catalyst. This transformation proceeds in neat conditions...

scholarly journals Oxidative coupling between C(sp2)–H and C(sp3)–H bonds of indoles and cyclic ethers/cycloalkanes

2016 ◽  
Vol 14 (9) ◽  
pp. 2608-2612 ◽  
Author(s):  
Qingjing Yang ◽  
Pui Ying Choy ◽  
Yinuo Wu ◽  
Baomin Fan ◽  
Fuk Yee Kwong
Keyword(s):  
Transition Metal ◽  
Oxidative Coupling ◽  
Cyclic Ethers ◽  
Metal Free ◽  
Dehydrogenative Coupling

Cross-dehydrogenative-coupling (CDC) between C–H/C–H bonds of indoles and cyclic ethers/cycloalkanes is made viable through a simple transition-metal-free pathway.

Cyclic ethers to esters and monoesters to bis-esters with unconventional coupling partners under metal free conditions via sp3 C–H functionalisation

2014 ◽  
Vol 50 (81) ◽  
pp. 12193-12196 ◽  
Author(s):  
Ganesh Majji ◽  
Srimanta Guin ◽  
Saroj K. Rout ◽  
Ahalya Behera ◽  
Bhisma K. Patel
Keyword(s):  
Cyclic Ethers ◽  
Oxidative Esterification ◽  
Metal Free

Oxidative esterification of sp3 C–H bonds in simple solvents has been achieved using latent ArCOO− sources under metal free conditions.

Sign in / Sign up

Export Citation Format

Share Document