scholarly journals Impact of Systemic versus Intratympanic Dexamethasone Administration on the Perilymph Proteome

2021 ◽  
Author(s):  
Betsy Szeto ◽  
Chris Valentini ◽  
Aykut Aksit ◽  
Emily G. Werth ◽  
Shahar Goeta ◽  
...  
Keyword(s):  
Intratympanic Dexamethasone

Role of intratympanic dexamethasone and diluted lignocaine in treatment of tinnitus

2019 ◽  
Vol 10 (3) ◽  
pp. 49-51
Author(s):  
Khatri M S ◽  
Keyword(s):  
Intratympanic Dexamethasone

scholarly journals Intratympanic steroid therapy for Bell’s palsy with poor prognostic results

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Akira Inagaki ◽  
Sachiyo Katsumi ◽  
Shinji Sekiya ◽  
Shingo Murakami
Keyword(s):  
Facial Nerve ◽  
Steroid Therapy ◽  
Standard Dose ◽  
Neuroprotective Effect ◽  
Bell’S Palsy ◽  
Control Group ◽  
Average Dose ◽  
Test Results ◽  
Bell's Palsy ◽  
Intratympanic Dexamethasone

AbstractIn Bell’s palsy, electrodiagnosis by electroneurography (ENoG) is widely used to predict a patient’s prognosis. The therapeutic options for patients with poor prognostic results remain controversial. Here, we investigated whether early intervention with intratympanic steroid therapy (ITST) is an effective treatment for Bell’s palsy patients with poor electrodiagnostic test results (≤ 10% electroneurography value). Patients in the concurrent ITST group (n = 8) received the standard systemic dose of prednisolone (410 mg total) and intratympanic dexamethasone (16.5 mg total) and those in the control group (n = 21) received systemic prednisolone at the standard dose or higher (average dose, 605 ± 27 mg). A year after onset, the recovery rate was higher in the ITST group than in the control group (88% vs 43%, P = 0.044). The average House-Brackmann grade was better in the concurrent ITST group (1.13 ± 0.13 vs 1.71 ± 0.16, P = 0.035). Concurrent ITST improves the facial nerve outcome in patients with poor electroneurography test results, regardless of whether equivalent or lower glucocorticoid doses were administered. This may be ascribed to a neuroprotective effect of ITST due to a higher dose of steroid reaching the lesion due to dexamethasone transfer in the facial nerve.

scholarly journals Intratympanic dexamethasone injection in Meniere′s disease

2015 ◽  
Vol 31 (2) ◽  
pp. 128 ◽  
Author(s):  
DaliaMohamed Hassan ◽  
Yasser Nafie ◽  
Ahmed Saadb ◽  
AdelA Maksoud
Keyword(s):  
Intratympanic Dexamethasone

Effects of intratympanic dexamethasone on noise-induced hearing loss: An experimental study

2018 ◽  
Vol 39 (1) ◽  
pp. 71-73 ◽  
Author(s):  
Sait Serdar Gumrukcu ◽  
İlhan Topaloglu ◽  
Ziya Salturk ◽  
Belgin Tutar ◽  
Yavuz Atar ◽  
...  
Keyword(s):  
Experimental Study ◽  
Hearing Loss ◽  
Noise Induced Hearing Loss ◽  
Intratympanic Dexamethasone

Comparison of the effects of the temperature of intratympanic dexamethasone injections on vertigo

2019 ◽  
Vol 40 (5) ◽  
pp. 653-655
Author(s):  
Nurdoğan Ata ◽  
Kayhan Öztürk ◽  
Bahri Gezgin
Keyword(s):  
Intratympanic Dexamethasone
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