Combination Therapy of Doxorubicin and Quercetin on Multidrug-Resistant Breast Cancer and Their Sequential Delivery by Reduction-Sensitive Hyaluronic Acid-Based Conjugate/d-α-Tocopheryl Poly(ethylene glycol) 1000 Succinate Mixed Micelles

2020 ◽  
Vol 17 (4) ◽  
pp. 1415-1427 ◽  
Author(s):  
Shuo Liu ◽  
Rui Li ◽  
Jin Qian ◽  
Jiabin Sun ◽  
Guowen Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Hyaluronic Acid ◽  
Combination Therapy ◽  
Ethylene Glycol ◽  
Mixed Micelles ◽  
Multidrug Resistant ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Selective chemotherapy and imaging of colorectal and breast cancer cells by a modified MUC-1 aptamer conjugated to a poly(ethylene glycol)-dimethacrylate coated Fe3O4–AuNCs nanocomposite

2019 ◽  
Vol 43 (1) ◽  
pp. 238-248 ◽  
Author(s):  
Roya Binaymotlagh ◽  
Farid Hajareh Haghighi ◽  
Fatemeh Aboutalebi ◽  
Seyede Zohreh Mirahmadi-Zare ◽  
Hassan Hadadzadeh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Targeted Therapy ◽  
Ethylene Glycol ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Molecular Medicine ◽  
Glycol Dimethacrylate ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Selective Chemotherapy

The combination of diagnosis and targeted therapy within a single nanoplatform is one of the remarkable advances in molecular medicine.

Mixed micelles of cetyltrimethylammonium bromide and poly(ethylene glycol)-600 monolaurate as catalysts of polyethylenimine phosphorylation in chloroform

2006 ◽  
Vol 55 (8) ◽  
pp. 1411-1418 ◽  
Author(s):  
G. A. Gainanova ◽  
E. P. Zhil’tsova ◽  
L. A. Kudryavtseva ◽  
S. V. Kharlamov ◽  
Sh. K. Latypov ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Cetyltrimethylammonium Bromide ◽  
Mixed Micelles ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Methoxy Poly(ethylene glycol)-Poly(lactide) Nanoparticles Encapsulating Quercetin Act as an Effective Anticancer Agent by Inducing Apoptosis in Breast Cancer

2014 ◽  
Vol 32 (2) ◽  
pp. 723-735 ◽  
Author(s):  
Garima Sharma ◽  
Jongbong Park ◽  
Ashish Ranjan Sharma ◽  
Jun-Sub Jung ◽  
Haesung Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Ethylene Glycol ◽  
Anticancer Agent ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Poly(ethylene glycol)–paclitaxel–alendronate self-assembled micelles for the targeted treatment of breast cancer bone metastases

Biomaterials ◽  
2013 ◽  
Vol 34 (15) ◽  
pp. 3795-3806 ◽  
Author(s):  
Keren Miller ◽  
Chiara Clementi ◽  
Dina Polyak ◽  
Anat Eldar-Boock ◽  
Liat Benayoun ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Ethylene Glycol ◽  
Bone Metastases ◽  
Targeted Treatment ◽  
Poly Ethylene Glycol ◽  
Self Assembled ◽  
Poly Ethylene

Mixed micelles from methoxy poly(ethylene glycol)–polylactide and methoxy poly(ethylene glycol)–poly(sebacic anhydride) copolymers as drug carriers

2012 ◽  
Vol 72 (11) ◽  
pp. 846-855 ◽  
Author(s):  
Po-Liang Lai ◽  
Cheng-Chun Hsu ◽  
Tsang-Hao Liu ◽  
Ding-Wei Hong ◽  
Lih-Huei Chen ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Mixed Micelles ◽  
Drug Carriers ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

A bioactive hyaluronic acid–based hydrogel cross-linked by Diels–Alder reaction for promoting neurite outgrowth of PC12 cells

2017 ◽  
Vol 32 (4) ◽  
pp. 382-396 ◽  
Author(s):  
Dongming Xing ◽  
Lie Ma ◽  
Changyou Gao
Keyword(s):  
Hyaluronic Acid ◽  
Ethylene Glycol ◽  
Neurite Outgrowth ◽  
Pc12 Cells ◽  
Alder Reaction ◽  
Poly Ethylene Glycol ◽  
Substitution Degree ◽  
Poly Ethylene

In order to improve neurite outgrowth on the in situ formed hyaluronic acid–based hydrogel, furan and methacrylate groups were grafted on hyaluronic acid successively. Furthermore, a laminin-derived peptide CQAASIKVAV was covalently immobilized via the Michael addition. The furan- and peptide-modified hyaluronic acid was then cross-linked in situ by mixing with bismaleimide poly(ethylene glycol) at 37 °C to obtain a bioactive hyaluronic acid–based hydrogel. The hyaluronic acid derivatives were characterized by 1H NMR and Fourier transform infrared spectroscopy. The gelation, swelling, and mechanical property of the hydrogels were analyzed. The modulus of the hydrogel could be tuned by changing furan substitution degree, while the peptide concentration could be changed by the ratio of furan- and peptide-modified hyaluronic acid with hyaluronic acid–furan. In vitro culture of PC12 cells showed that the longest neurite outgrowth appeared on the hyaluronic acid–poly(ethylene glycol) hydrogel with the highest peptide content (the substitution degree of peptide in furan- and peptide-modified hyaluronic acid was 23 %) and a lower threshold modulus of 4.5 kPa. The furan and methacrylate-functionalized hyaluronic acid provides a versatile platform for diverse functionalization and can be used for modulation of other cell behaviors as well.

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