Adding Dynamic Biomolecule Signaling to Hydrogel Systems via Tethered Photolabile Cell-Adhesive Proteins

Author(s):  
Rachel Chapla ◽  
Joshua A. Hammer ◽  
Jennifer L. West
1993 ◽  
Vol 113 (1) ◽  
pp. 29-35 ◽  
Author(s):  
Toshinaga Maeda ◽  
Rieko Oyama ◽  
Koiti Titani ◽  
Kiyotoshi Sekiguchi

Biologicals ◽  
2007 ◽  
Vol 35 (4) ◽  
pp. 247-257 ◽  
Author(s):  
Akiko Ishii-Watabe ◽  
Toshie Kanayasu-Toyoda ◽  
Takuo Suzuki ◽  
Tetsu Kobayashi ◽  
Teruhide Yamaguchi ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Qi Chen ◽  
Donghui Zhang ◽  
Wenjing Zhang ◽  
Haodong Zhang ◽  
Jingcheng Zou ◽  
...  

AbstractCell adhesion has tremendous impact on the function of culture platforms and implants. Cell-adhesive proteins and peptides have been extensively used for decades to promote cell adhesion, however, their application suffers from their easy enzymatic degradation, difficulty in large-scale preparation and expensiveness. To develop the next-generation cell-adhesive materials, we mimic the cell adhesion functions and mechanisms of RGD and KRSR peptides and design cell-adhesive cationic-hydrophobic amphiphilic β-amino acid polymers that are stable upon proteolysis and easily prepared in large scale at low cost. The optimal polymer strongly promotes cell adhesion, using preosteoblast cell as a model, by following dual mechanisms that are independent of sequence and chirality of the statistic copolymer. Our strategy opens avenues in designing the next-generation cell-adhesive materials and may guide future studies and applications.


2018 ◽  
Vol 10 (2) ◽  
pp. 025001 ◽  
Author(s):  
Yu Bin Lee ◽  
Joong-yup Lee ◽  
Hayeon Byun ◽  
Taufiq Ahmad ◽  
Mitsuru Akashi ◽  
...  

2007 ◽  
Vol 129 (16) ◽  
pp. 4874-4875 ◽  
Author(s):  
Isaac S. Carrico ◽  
Stacey A. Maskarinec ◽  
Sarah C. Heilshorn ◽  
Marissa L. Mock ◽  
Julie C. Liu ◽  
...  

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