Structure–Activity Relationship Studies of 6α- and 6β-Indolylacetamidonaltrexamine Derivatives as Bitopic Mu Opioid Receptor Modulators and Elaboration of the “Message-Address Concept” To Comprehend Their Functional Conversion

Mu Opioid Receptor ◽

Activity Relationship ◽

Mu Opioid ◽

Structure Activity ◽

Discovery, structure–activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.07.012 ◽

2014 ◽

Vol 22 (17) ◽

pp. 4694-4703 ◽

Cited By ~ 8

Author(s):

Ming-Fu Cheng ◽

Li-Chin Ou ◽

Shu-Chun Chen ◽

Wan-Ting Chang ◽

Ping-Yee Law ◽

...

Keyword(s):

Opioid Receptor ◽

Activity Relationship ◽

Receptor Agonists ◽

Structure Activity ◽

Structure-Activity Relationships of Nociceptin Receptor (NOP) Ligands and the Design of Bifunctional NOP/Mu Opioid Receptor-Targeted Ligands

ACS Symposium Series - Research and Development of Opioid-Related Ligands ◽

10.1021/bk-2013-1131.ch008 ◽

2013 ◽

pp. 145-160 ◽

Cited By ~ 4

Author(s):

Nurulain T. Zaveri ◽

Dennis Yasuda ◽

Blair V. Journigan ◽

Pankaj R. Daga ◽

Faming Jiang ◽

...

Keyword(s):

Opioid Receptor ◽

Mu Opioid Receptor ◽

Mu Opioid ◽

Structure Activity Relationships ◽

Structure Activity ◽

Nociceptin Receptor

Design, Synthesis, and Structure–Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective μ Opioid Receptor Agonists

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.0c00487 ◽

2020 ◽

Author(s):

Huoming Huang ◽

Xinwei Li ◽

Wei Guo ◽

Chen Zhu ◽

Yuanyuan Qian ◽

...

Keyword(s):

Opioid Receptor ◽

Activity Relationship ◽

Design Synthesis ◽

Receptor Agonists ◽

Structure Activity ◽

Μ Opioid Receptor ◽

The Structure–Activity Relationship of a Tetrahydroisoquinoline Class ofN-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-ContainingN-Methyl-d-Aspartate Receptors

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.7b00239 ◽

2017 ◽

Vol 60 (13) ◽

pp. 5556-5585 ◽

Cited By ~ 10

Author(s):

Katie L. Strong ◽

Matthew P. Epplin ◽

John Bacsa ◽

Christopher J. Butch ◽

Pieter B. Burger ◽

...

Keyword(s):

Activity Relationship ◽

Aspartate Receptor ◽

Structure Activity ◽

Relationship Of ◽

Structure activity relationship studies of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3′-carboxamido)morphinan (NAQ) analogues as potent opioid receptor ligands: Preliminary results on the role of electronic characteristics for affinity and function

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.07.043 ◽

2013 ◽

Vol 23 (18) ◽

pp. 5045-5048 ◽

Cited By ~ 7

Author(s):

Yunyun Yuan ◽

Orgil Elbegdorj ◽

Irina O. Beletskaya ◽

Dana E. Selley ◽

Yan Zhang

Keyword(s):

Opioid Receptor ◽

Activity Relationship ◽

Receptor Ligands ◽

Preliminary Results ◽

Structure Activity ◽

Opioid Receptor Ligands ◽

And Function

A Structure–Activity Relationship Study and Combinatorial Synthetic Approach of C-Terminal Modified Bifunctional Peptides That Are δ/μ Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm070332f ◽

2008 ◽

Vol 51 (5) ◽

pp. 1369-1376 ◽

Cited By ~ 36

Author(s):

Takashi Yamamoto ◽

Padma Nair ◽

Josef Vagner ◽

Tally Largent-Milnes ◽

Peg Davis ◽

...

Keyword(s):

Opioid Receptor ◽

Activity Relationship ◽

Synthetic Approach ◽

Neurokinin 1 Receptor ◽

Structure Activity ◽

Μ Opioid Receptor ◽

Relationship Study ◽

Neurokinin 1 ◽

Structure–Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.5b00092 ◽

2015 ◽

Vol 6 (8) ◽

pp. 1411-1419 ◽

Cited By ~ 36

Author(s):

Kimberly M. Lovell ◽

Kevin J. Frankowski ◽

Edward L. Stahl ◽

Stephen R. Slauson ◽

Euna Yoo ◽

...

Keyword(s):

G Protein ◽

Opioid Receptor ◽

Kappa Opioid Receptor ◽

Activity Relationship ◽

Kappa Opioid ◽

Receptor Agonists ◽

Structure Activity ◽

Selective Estrogen Receptor Modulators with Conformationally Restricted Side Chains. Synthesis and Structure−Activity Relationship of ERα-Selective Tetrahydroisoquinoline Ligands

Journal of Medicinal Chemistry ◽

10.1021/jm040858p ◽

2005 ◽

Vol 48 (2) ◽

pp. 364-379 ◽

Cited By ~ 43

Author(s):

Johanne Renaud ◽

Serge François Bischoff ◽

Thomas Buhl ◽

Philipp Floersheim ◽

Brigitte Fournier ◽

...

Keyword(s):

Estrogen Receptor ◽

Selective Estrogen Receptor Modulators ◽

Activity Relationship ◽

Side Chains ◽

Conformationally Restricted ◽

Estrogen Receptor Modulators ◽

Structure Activity ◽

Relationship Of ◽

Structure-Activity Relationship Study of Nonpeptideδ-Opioid Receptor Ligands

Helvetica Chimica Acta ◽

10.1002/1522-2675(20011114)84:11<3299::aid-hlca3299>3.0.co;2-b ◽

2001 ◽

Vol 84 (11) ◽

pp. 3299-3305 ◽

Cited By ~ 4

Author(s):

Joaquín Lahsen ◽

Helmut Schmidhammer ◽

Bernd M. Rode

Keyword(s):

Opioid Receptor ◽

Activity Relationship ◽

Receptor Ligands ◽

Structure Activity ◽

Opioid Receptor Ligands ◽

Relationship Study

Structure–activity relationship of nonsecosteroidal vitamin D receptor modulators

Trends in Pharmacological Sciences ◽

10.1016/j.tips.2014.04.008 ◽

2014 ◽

Vol 35 (7) ◽

pp. 324-337 ◽

Cited By ~ 28

Author(s):

Sachiko Yamada ◽

Makoto Makishima

Keyword(s):

Vitamin D ◽

Vitamin D Receptor ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of ◽