Plasmodium chabaudi Affects Mast Cell Degranulation as Measured by Carbon-Fiber Microelectrode Amperometry

2021 ◽  
Author(s):  
Kang Xiong-Hang ◽  
Christy L. Haynes
Keyword(s):  
Mast Cell ◽  
Carbon Fiber ◽  
Mast Cell Degranulation ◽  
Plasmodium Chabaudi ◽  
Carbon Fiber Microelectrode

Mode of Mast Cell Degranulation

1971 ◽  
Vol 33 (3) ◽  
pp. 223-228
Author(s):  
Shojiro MORIYASU
Keyword(s):  
Mast Cell ◽  
Mast Cell Degranulation

Electrochemical treatment in KOH renews and activates carbon fiber microelectrode surfaces

2021 ◽  
Author(s):  
Qun Cao ◽  
Julia Lucktong ◽  
Zijun Shao ◽  
Yuanyu Chang ◽  
B. Jill Venton
Keyword(s):  
Carbon Fiber ◽  
Electrochemical Treatment ◽  
Carbon Fiber Microelectrode

Transcutaneous systemic photobiomodulation reduced lung inflammation in experimental model of asthma by altering the mast cell degranulation and interleukin 10 level

2021 ◽  
Author(s):  
Paula Tatiane Alonso ◽  
Adriana Schapochnik ◽  
Simone Klein ◽  
Robson Brochetti ◽  
Amílcar Sabino Damazo ◽  
...  
Keyword(s):  
Mast Cell ◽  
Experimental Model ◽  
Lung Inflammation ◽  
Interleukin 10 ◽  
Mast Cell Degranulation

scholarly journals Platelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils and Mast Cell Degranulation

2021 ◽  
Vol 22 (14) ◽  
pp. 7360
Author(s):  
Angie De La Cruz ◽  
Aubrey Hargrave ◽  
Sri Magadi ◽  
Justin A. Courson ◽  
Paul T. Landry ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Types ◽  
Mast Cell Degranulation ◽  
Wild Type ◽  
Delayed Wound Healing ◽  
Corneal Epithelial ◽  
Corneal Abrasion ◽  
Low Levels ◽  
Endothelial Pores

Platelet extravasation during inflammation is under-appreciated. In wild-type (WT) mice, a central corneal epithelial abrasion initiates neutrophil (PMN) and platelet extravasation from peripheral limbal venules. The same injury in mice expressing low levels of the β2-integrin, CD18 (CD18hypo mice) shows reduced platelet extravasation with PMN extravasation apparently unaffected. To better define the role of CD18 on platelet extravasation, we focused on two relevant cell types expressing CD18: PMNs and mast cells. Following corneal abrasion in WT mice, we observed not only extravasated PMNs and platelets but also extravasated erythrocytes (RBCs). Ultrastructural observations of engorged limbal venules showed platelets and RBCs passing through endothelial pores. In contrast, injured CD18hypo mice showed significantly less venule engorgement and markedly reduced platelet and RBC extravasation; mast cell degranulation was also reduced compared to WT mice. Corneal abrasion in mast cell-deficient (KitW-sh/W-sh) mice showed less venule engorgement, delayed PMN extravasation, reduced platelet and RBC extravasation and delayed wound healing compared to WT mice. Finally, antibody-induced depletion of circulating PMNs prior to corneal abrasion reduced mast cell degranulation, venule engorgement, and extravasation of PMNs, platelets, and RBCs. In summary, in the injured cornea, platelet and RBC extravasation depends on CD18, PMNs, and mast cell degranulation.

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