Ultrasound-Induced Magnetic Imaging of Tumors Targeted by Biofunctional Magnetic Nanoparticles

TiO2 nanoparticles with embedded magnetite were suspended in aqueous HAuCl4 and ultraviolet irradiated to photodeposit gold on the surface. The degree of gold coating and the wavelength of absorbance could be controlled by adjusting [HAuCl4]. Absorbance maxima were between 540-590 nm. Particles exhibited superparamagnetic properties (blocking temperature ∼170 K) whether or not coated with gold. These particles have potential applications as drug delivery agents, magnetic imaging contrast agents, and magnetically separatable photocatalysts with unique surface properties.

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Zero-loss omega-filtered REM and RHEED on the new Zeiss 912

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100087392 ◽

1991 ◽

Vol 49 ◽

pp. 616-617

Author(s):

J.C.H. Spence ◽

J. Mayer

Keyword(s):

Electron Microscopy ◽

Materials Science ◽

Surface States ◽

Ccd Camera ◽

Dark Field ◽

Ion Pump ◽

Magnetic Imaging ◽

Reflection Electron Microscopy ◽

Diffraction Patterns ◽

Large Background

The Zeiss 912 is a new fully digital, side-entry, 120 Kv TEM/STEM instrument for materials science, fitted with an omega magnetic imaging energy filter. Pumping is by turbopump and ion pump. The magnetic imaging filter allows energy-filtered images or diffraction patterns to be recorded without scanning using efficient parallel (area) detection. The energy loss intensity distribution may also be displayed on the screen, and recorded by scanning it over the PMT supplied. If a CCD camera is fitted and suitable new software developed, “parallel ELS” recording results. For large fields of view, filtered images can be recorded much more efficiently than by Scanning Reflection Electron Microscopy, and the large background of inelastic scattering removed. We have therefore evaluated the 912 for REM and RHEED applications. Causes of streaking and resonance in RHEED patterns are being studied, and a more quantitative analysis of CBRED patterns may be possible. Dark field band-gap REM imaging of surface states may also be possible.

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Electron spectroscopic imaging and diffraction

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100087847 ◽

1991 ◽

Vol 49 ◽

pp. 706-707

Author(s):

M. Rühle ◽

J. Mayer ◽

J.C.H. Spence ◽

J. Bihr ◽

W. Probst ◽

...

Keyword(s):

Materials Science ◽

Electron Spectroscopic Imaging ◽

Magnetic Filter ◽

Magnetic Imaging ◽

Illumination System ◽

Probe Size ◽

Diffraction Patterns ◽

Fritz Haber ◽

Koehler Illumination ◽

First Time

A new Zeiss TEM with an imaging Omega filter is a fully digitized, side-entry, 120 kV TEM/STEM instrument for materials science. The machine possesses an Omega magnetic imaging energy filter (see Fig. 1) placed between the third and fourth projector lens. Lanio designed the filter and a prototype was built at the Fritz-Haber-Institut in Berlin, Germany. The imaging magnetic filter allows energy-filtered images or diffraction patterns to be recorded without scanning using efficient area detection. The energy dispersion at the exit slit (Fig. 1) results in ∼ 1.5 μm/eV which allows imaging with energy windows of ≤ 10 eV. The smallest probe size of the microscope is 1.6 nm and the Koehler illumination system is used for the first time in a TEM. Serial recording of EELS spectra with a resolution < 1 eV is possible. The digital control allows X,Y,Z coordinates and tilt settings to be stored and later recalled.

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Nanoarmoring of Enzymes with Carbon Nanotubes and Magnetic Nanoparticles

10.1016/s0076-6879(20)x0002-4 ◽

2020 ◽

Keyword(s):

Carbon Nanotubes ◽

Magnetic Nanoparticles

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Thermal Conductivity of Nanofluid with Magnetic Nanoparticles

PIERS Online ◽

10.2529/piers080904124024 ◽

2009 ◽

Vol 5 (3) ◽

pp. 231-234 ◽

Cited By ~ 12

Author(s):

Tsung-Han Tsai ◽

Long-Sheng Kuo ◽

Ping-Hei Chen ◽

Chin-Ting Yang

Keyword(s):

Thermal Conductivity ◽

Magnetic Nanoparticles

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Ferromagnetic Resonance Biosensor for Homogeneous and Volumetric Detection of DNA

10.26434/chemrxiv.5662315.v1 ◽

2017 ◽

Author(s):

Bo Tian ◽

Peter Svedlindh ◽

Mattias Strömberg ◽

Erik Wetterskog

Keyword(s):

Magnetic Nanoparticles ◽

Ferromagnetic Resonance ◽

Limit Of Detection ◽

Point Of Care ◽

Rolling Circle Amplification ◽

Resonance Field ◽

Isothermal Amplification ◽

Detection Sensitivity ◽

Serum Samples ◽

Rolling Circle

In this work, we demonstrate for the first time, a ferromagnetic resonance (FMR) based homogeneous and volumetric biosensor for magnetic label detection. Two different isothermal amplification methods, i.e., rolling circle amplification (RCA) and loop-mediated isothermal amplification (LAMP) are adopted and combined with a standard electron paramagnetic resonance (EPR) spectrometer for FMR biosensing. For RCA-based FMR biosensor, binding of RCA products of a synthetic Vibrio cholerae target DNA sequence gives rise to the formation of aggregates of magnetic nanoparticles. Immobilization of nanoparticles within the aggregates leads to a decrease of the net anisotropy of the system and a concomitant increase of the resonance field. A limit of detection of 1 pM is obtained with an average coefficient of variation of 0.16%, which is superior to the performance of other reported RCA-based magnetic biosensors. For LAMP-based sensing, a synthetic Zika virus target oligonucleotide is amplified and detected in 20% serum samples. Immobilization of magnetic nanoparticles is induced by their co-precipitation with Mg2P2O7 (a by-product of LAMP) and provides a detection sensitivity of 100 aM. The fast measurement, high sensitivity and miniaturization potential of the proposed FMR biosensing technology makes it a promising candidate for designing future point-of-care devices.

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