Artificially Engineered Cubic Iron Oxide Nanoparticle as a High-Performance Magnetic Particle Imaging Tracer for Stem Cell Tracking

ACS Nano ◽  
2020 ◽  
Vol 14 (2) ◽  
pp. 2053-2062 ◽  
Author(s):  
Qiyue Wang ◽  
Xibo Ma ◽  
Hongwei Liao ◽  
Zeyu Liang ◽  
Fangyuan Li ◽  
...  
Keyword(s):  
Stem Cell ◽  
Iron Oxide ◽  
High Performance ◽  
Cell Tracking ◽  
Magnetic Particle ◽  
Iron Oxide Nanoparticle ◽  
Stem Cell Tracking ◽  
Magnetic Particle Imaging ◽  
Oxide Nanoparticle ◽  
Particle Imaging

scholarly journals Evaluation of Iron Oxide Nanoparticle Micelles for Magnetic Particle Imaging (MPI) of Thrombosis

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0119257 ◽  
Author(s):  
Lucas W. E. Starmans ◽  
Rik P. M. Moonen ◽  
Erica Aussems-Custers ◽  
Mat J. A. P. Daemen ◽  
Gustav J. Strijkers ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Magnetic Particle ◽  
Iron Oxide Nanoparticle ◽  
Magnetic Particle Imaging ◽  
Oxide Nanoparticle ◽  
Particle Imaging

scholarly journals Magnetic Particle Imaging With Tailored Iron Oxide Nanoparticle Tracers

2015 ◽  
Vol 34 (5) ◽  
pp. 1077-1084 ◽  
Author(s):  
R. Matthew Ferguson ◽  
Amit P. Khandhar ◽  
Scott J. Kemp ◽  
Hamed Arami ◽  
Emine U. Saritas ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Magnetic Particle ◽  
Iron Oxide Nanoparticle ◽  
Magnetic Particle Imaging ◽  
Oxide Nanoparticle ◽  
Particle Imaging

scholarly journals Iron Oxide Nanoparticle-Micelles (ION-Micelles) for Sensitive (Molecular) Magnetic Particle Imaging and Magnetic Resonance Imaging

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e57335 ◽  
Author(s):  
Lucas W. E. Starmans ◽  
Dirk Burdinski ◽  
Nicole P. M. Haex ◽  
Rik P. M. Moonen ◽  
Gustav J. Strijkers ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Magnetic Particle ◽  
Iron Oxide Nanoparticle ◽  
Resonance Imaging ◽  
Magnetic Particle Imaging ◽  
Oxide Nanoparticle ◽  
Particle Imaging

scholarly journals Complex Relationship between Iron Oxide Nanoparticle Degradation and the Signal Intensity in Magnetic Particle Imaging

2020 ◽  
Vol 3 (5) ◽  
pp. 3991-3999
Author(s):  
Julia Guzy ◽  
Shatadru Chakravarty ◽  
Foster J. Buchanan ◽  
Haoran Chen ◽  
Jeffrey M. Gaudet ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Signal Intensity ◽  
Magnetic Particle ◽  
Iron Oxide Nanoparticle ◽  
Complex Relationship ◽  
Magnetic Particle Imaging ◽  
Oxide Nanoparticle ◽  
Particle Imaging

High-performance iron oxide nanoparticles for magnetic particle imaging – guided hyperthermia (hMPI)

Nanoscale ◽  
2016 ◽  
Vol 8 (24) ◽  
pp. 12162-12169 ◽  
Author(s):  
Lisa M. Bauer ◽  
Shu F. Situ ◽  
Mark A. Griswold ◽  
Anna Cristina S. Samia
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
High Performance ◽  
Magnetic Particle ◽  
Oxide Nanoparticles ◽  
Magnetic Particle Imaging ◽  
Particle Imaging

Quantitative stem cell imaging with magnetic particle imaging

2013 ◽  
Author(s):  
Bo Zheng ◽  
T. Vazin ◽  
W. Yang ◽  
P. W. Goodwill ◽  
E. U. Saritas ◽  
...  
Keyword(s):  
Stem Cell ◽  
Magnetic Particle ◽  
Cell Imaging ◽  
Magnetic Particle Imaging ◽  
Particle Imaging

Zero valent iron core–iron oxide shell nanoparticles as small magnetic particle imaging tracers

2020 ◽  
Vol 56 (24) ◽  
pp. 3504-3507 ◽  
Author(s):  
Lucy Gloag ◽  
Milad Mehdipour ◽  
Marina Ulanova ◽  
Kevin Mariandry ◽  
Muhammad Azrhy Nichol ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Magnetic Nanoparticle ◽  
Magnetic Particle ◽  
Zero Valent Iron ◽  
Oxide Shell ◽  
Iron Core ◽  
Shell Nanoparticles ◽  
Magnetic Particle Imaging ◽  
Nanoparticle Imaging ◽  
Particle Imaging

Zero valent iron core–iron oxide shell nanoparticles coated with a multi-phosphonate brush co-polymer are shown to be small and effective magnetic nanoparticle imaging tracers.

scholarly journals Targeted Delivery of Iron Oxide Nanoparticle-Loaded Human Embryonic Stem Cell-Derived Spherical Neural Masses for Treating Intracerebral Hemorrhage

2020 ◽  
Vol 21 (10) ◽  
pp. 3658
Author(s):  
Min Kyoung Kang ◽  
Tae Jung Kim ◽  
Young-Ju Kim ◽  
Lamie Kang ◽  
Jonghoon Kim ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Stem Cells ◽  
Stem Cell ◽  
Iron Oxide ◽  
External Magnetic Field ◽  
Targeted Delivery ◽  
Human Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Iron Oxide Nanoparticle ◽  
Oxide Nanoparticle

This study evaluated the potential of iron oxide nanoparticle-loaded human embryonic stem cell (ESC)-derived spherical neural masses (SNMs) to improve the transportation of stem cells to the brain, ameliorate brain damage from intracerebral hemorrhage (ICH), and recover the functional status after ICH under an external magnetic field of a magnet attached to a helmet. At 24 h after induction of ICH, rats were randomly separated into three experimental groups: ICH with injection of phosphate-buffered saline (PBS group), ICH with intravenous injection of magnetosome-like ferrimagnetic iron oxide nanocubes (FION)-labeled SNMs (SNMs* group), and ICH with intravenous injection of FION-labeled SNMs followed by three days of external magnetic field exposure for targeted delivery by a magnet-embedded helmet (SNMs*+Helmet group). On day 3 after ICH induction, an increased Prussian blue-stained area and decreased swelling volume were observed in the SNMs*+Helmet group compared with that of the other groups. A significantly decreased recruitment of macrophages and neutrophils and a downregulation of pro-inflammatory cytokines followed by improved neurological function three days after ICH were observed in the SNMs*+Helmet group. Hemispheric atrophy at six weeks after ICH was significantly decreased in the SNMs*+Helmet group compared with that of the PBS group. In conclusion, we have developed a targeted delivery system using FION tagged to stem cells and a magnet-embedded helmet. The targeted delivery of SNMs might have the potential for developing novel therapeutic strategies for ICH.

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