scholarly journals Molecular Dynamics Analysis of Binding Sites of Epidermal Growth Factor Receptor Kinase Inhibitors

ACS Omega ◽  
2020 ◽  
Vol 5 (26) ◽  
pp. 16307-16314
Author(s):  
Dong-Dong Li ◽  
Ting-Ting Wu ◽  
Pan Yu ◽  
Zhen-Zhong Wang ◽  
Wei Xiao ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Binding Sites ◽  
Kinase Inhibitors ◽  
Growth Factor Receptor ◽  
Dynamics Analysis ◽  
Receptor Kinase ◽  
Epidermal Growth

scholarly journals Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent

2018 ◽  
Vol 54 (54) ◽  
pp. 7479-7482 ◽  
Author(s):  
Mu Yang ◽  
Hanzhi Wu ◽  
Julie Chu ◽  
Lucas A. Gabriel ◽  
Y. Kim ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Kinase Inhibitors ◽  
Growth Factor Receptor ◽  
Cysteine Residue ◽  
Receptor Kinase ◽  
Epidermal Growth ◽  
Hybrid Agent ◽  
Egfr Kinase

Platinum-modified tyrosine kinase inhibitors show strong and selective EGFR kinase binding and form adducts with a pharmacologically relevant cysteine residue.

Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors

2006 ◽  
Vol 16 (6) ◽  
pp. 1643-1646 ◽  
Author(s):  
Leon Smith ◽  
Evgueni L. Piatnitski ◽  
Alexander S. Kiselyov ◽  
Xiaohu Ouyang ◽  
Xiaoling Chen ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Kinase Inhibitors ◽  
Growth Factor Receptor ◽  
Receptor Kinase ◽  
Epidermal Growth
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