The Substrate Binding Site of Human Liver Cytochrome P450 2C9: An Approach Using Designed Tienilic Acid Derivatives and Molecular Modeling

Biochemistry ◽  
1995 ◽  
Vol 34 (33) ◽  
pp. 10365-10375 ◽  
Author(s):  
Annah Mancy ◽  
Pierre Broto ◽  
Sylvie Dijols ◽  
Patrick M. Dansette ◽  
Daniel Mansuy
Keyword(s):  
Cytochrome P450 ◽  
Molecular Modeling ◽  
Binding Site ◽  
Human Liver ◽  
Substrate Binding ◽  
Cytochrome P450 2C9 ◽  
Tienilic Acid ◽  
Substrate Binding Site ◽  
Liver Cytochrome

The Substrate Binding Site of Human Liver Cytochrome P450 2C9:  An NMR Study†

Biochemistry ◽  
1997 ◽  
Vol 36 (42) ◽  
pp. 12672-12682 ◽  
Author(s):  
Sonia Poli-Scaife ◽  
Roger Attias ◽  
Patrick M. Dansette ◽  
Daniel Mansuy
Keyword(s):  
Cytochrome P450 ◽  
Binding Site ◽  
Human Liver ◽  
Substrate Binding ◽  
Cytochrome P450 2C9 ◽  
Substrate Binding Site ◽  
Liver Cytochrome ◽  
Nmr Study

Pyrene·Pyrene Complexes at the Active Site of Cytochrome P450 3A4:  Evidence for a Multiple Substrate Binding Site

2002 ◽  
Vol 124 (40) ◽  
pp. 11866-11867 ◽  
Author(s):  
Michael J. Dabrowski ◽  
Michael L. Schrag ◽  
Larry C. Wienkers ◽  
William M. Atkins
Keyword(s):  
Cytochrome P450 ◽  
Binding Site ◽  
Active Site ◽  
Substrate Binding ◽  
Cytochrome P450 3A4 ◽  
Substrate Binding Site ◽  
Multiple Substrate

Molecular modeling of the HIV-1 protease and its substrate binding site

Science ◽  
1989 ◽  
Vol 243 (4893) ◽  
pp. 928-931 ◽  
Author(s):  
I. Weber ◽  
M Miller ◽  
M Jaskolski ◽  
J Leis ◽  
A. Skalka ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Binding Site ◽  
Substrate Binding ◽  
Substrate Binding Site ◽  
Hiv 1
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