Characterization of a recombinant extracellular domain of the type 1 tumor necrosis factor receptor: evidence for tumor necrosis factor .alpha. induced receptor aggregation

Biochemistry ◽  
1992 ◽  
Vol 31 (4) ◽  
pp. 1134-1141 ◽  
Author(s):  
Diane Pennica ◽  
William J. Kohr ◽  
Brian M. Fendly ◽  
Steven J. Shire ◽  
Helga E. Raab ◽  
...  
2005 ◽  
Vol 73 (12) ◽  
pp. 8437-8441 ◽  
Author(s):  
Hyosun Cho ◽  
David N. McMurray

ABSTRACT Neutralization of tumor necrosis factor alpha (TNF-α) significantly down-regulated antigen-induced lymphoproliferation and the expression of interleukin-12 p40 and gamma interferon mRNA and enhanced the viability of intracellular attenuated and virulent mycobacteria in cocultures of immune T cells and macrophages obtained from Mycobacterium bovis BCG-vaccinated guinea pigs. This suggests the crucial role of TNF-α in the activation of a type 1 T-cell response against Mycobacterium tuberculosis infection.


2016 ◽  
Vol 53 (6) ◽  
pp. 1049-1051 ◽  
Author(s):  
Sarah S. Farabi ◽  
David W. Carley ◽  
Rand T. Akasheh ◽  
Lauretta Quinn

Pain Practice ◽  
2013 ◽  
Vol 13 (8) ◽  
pp. 649-656 ◽  
Author(s):  
Elon Eisenberg ◽  
Ifat Sandler ◽  
Roi Treister ◽  
Erica Suzan ◽  
May Haddad

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