Direct Measurement of Acylenzyme Hydrolysis Demonstrates Rate-Limiting Deacylation in Cleavage of Physiological Sequences by the Processing Protease Kex2†

Biochemistry ◽  
2001 ◽  
Vol 40 (12) ◽  
pp. 3657-3665 ◽  
Author(s):  
Nathan C. Rockwell ◽  
Robert S. Fuller
Keyword(s):  
Direct Measurement ◽  
Processing Protease ◽  
Rate Limiting

Direct Measurement of the Listening of Hearing-Impaired Children

1970 ◽  
Vol 13 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Mary Mira
Keyword(s):  
Direct Measurement ◽  
Continuous Measurement ◽  
Hearing Impaired ◽  
Reinforcement System ◽  
School Aged Children ◽  
Conjugate Reinforcement ◽  
Impaired Children ◽  
Hearing Impaired Children

Listening, a significant dimension of the behavior of hearing-impaired children, may be measured directly by recording childrens' responses to obtain audio narrations programmed via a conjugate reinforcement system. Twelve hearing-impaired, school-aged children responded in varying ways to the opportunity to listen. Direct and continuous measurement of listening has relevance for evaluation of remediation methods and for discovery of variables potentially related to listening.

DIRECT MEASUREMENT OF TILT ANGLE IN SMECTIC MESOPHASES BY NEUTRON DIFFRACTION

1976 ◽  
Vol 37 (C3) ◽  
pp. C3-127-C3-127 ◽  
Author(s):  
H. HERVET ◽  
S. LAGOMARSINO ◽  
F. RUSTICHELLI ◽  
F. VOLINO
Keyword(s):  
Neutron Diffraction ◽  
Direct Measurement ◽  
Tilt Angle

Ornithine Decarboxylase Activity in Cultured Endothelial Cells Stimulated by Serum, Thrombin and Serotonin

1978 ◽  
Vol 39 (02) ◽  
pp. 496-503 ◽  
Author(s):  
P A D’Amore ◽  
H B Hechtman ◽  
D Shepro
Keyword(s):  
Endothelial Cells ◽  
Ornithine Decarboxylase ◽  
Decarboxylase Activity ◽  
Aortic Endothelial Cells ◽  
Ornithine Decarboxylase Activity ◽  
Rate Limiting Step ◽  
Bovine Aortic Endothelial Cells ◽  
Limiting Step ◽  
Rate Limiting ◽  
Serum Serotonin

SummaryOrnithine decarboxylase (ODC) activity, the rate-limiting step in the synthesis of polyamines, can be demonstrated in cultured, bovine, aortic endothelial cells (EC). Serum, serotonin and thrombin produce a rise in ODC activity. The serotonin-induced ODC activity is significantly blocked by imipramine (10-5 M) or Lilly 11 0140 (10-6M). Preincubation of EC with these blockers together almost completely depresses the 5-HT-stimulated ODC activity. These observations suggest a manner by which platelets may maintain EC structural and metabolic soundness.

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