Enhanced Peptide Nucleic Acid Binding to Supercoiled DNA: Possible Implications for DNA “Breathing” Dynamics†

Biochemistry ◽

10.1021/bi960436k ◽

1996 ◽

Vol 35 (27) ◽

pp. 8863-8869 ◽

Author(s):

Thomas Bentin ◽

Peter E. Nielsen

Keyword(s):

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Nucleic Acid Binding ◽

Supercoiled Dna

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GW27-e0210 Ultrasound-targeted microbubbles combined with a peptide nucleic acid binding nuclear localization signal mediates the transfection of exogenous genes by improving both cytoplasmic and nuclear import

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2016.07.203 ◽

2016 ◽

Vol 68 (16) ◽

pp. C55

Author(s):

Jiang Nan ◽

Ruigiang Guo

Keyword(s):

Nucleic Acid ◽

Nuclear Localization ◽

Nuclear Import ◽

Nuclear Localization Signal ◽

Peptide Nucleic Acid ◽

Nucleic Acid Binding ◽

Localization Signal ◽

Targeted Microbubbles ◽

Exogenous Genes

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Insight into why pyrrolidinyl peptide nucleic acid binding to DNA is more stable than the DNA·DNA duplex

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2008.05.102 ◽

2008 ◽

Vol 372 (4) ◽

pp. 765-771 ◽

Author(s):

Khatcharin Siriwong ◽

Parawan Chuichay ◽

Suwipa Saen-oon ◽

Chaturong Suparpprom ◽

Tirayut Vilaivan ◽

...

Keyword(s):

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Nucleic Acid Binding ◽

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Quinoxaline Antibiotics Enhance Peptide Nucleic Acid Binding to Double-Stranded DNA†

Biochemistry ◽

10.1021/bi000254x ◽

2000 ◽

Vol 39 (31) ◽

pp. 9502-9507 ◽

Author(s):

Niels Erik Møllegaard ◽

Christian Bailly ◽

Michael J. Waring ◽

Peter E. Nielsen

Keyword(s):

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Nucleic Acid Binding ◽

Double Stranded Dna

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Site-specific cleavage of mutant ABL mRNA by DNAzyme is facilitated by peptide nucleic acid binding to RNA substrate

FEBS Letters ◽

10.1016/j.febslet.2012.09.013 ◽

2012 ◽

Vol 586 (21) ◽

pp. 3865-3869 ◽

Author(s):

Ji Eun Kim ◽

Soojin Yoon ◽

Hyejung Mok ◽

Woong Jung ◽

Dong-Eun Kim

Keyword(s):

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Nucleic Acid Binding ◽

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Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.7.2637 ◽

1995 ◽

Vol 92 (7) ◽

pp. 2637-2641 ◽

Author(s):

V. V. Demidov ◽

M. V. Yavnilovich ◽

B. P. Belotserkovskii ◽

M. D. Frank-Kamenetskii ◽

P. E. Nielsen

Keyword(s):

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Kinetics And Mechanism ◽

Nucleic Acid Binding

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Ultrasound-Targeted Microbubbles Combined with a Peptide Nucleic Acid Binding Nuclear Localization Signal Mediates the Transfection of Exogenous Genes by Improving both Cytoplasmic and Nuclear Import

Ultrasound in Medicine & Biology ◽

10.1016/j.ultrasmedbio.2017.08.971 ◽

2017 ◽

Vol 43 ◽

pp. S11 ◽

Author(s):

Ruiqiang Guo ◽

Jiang Nan

Keyword(s):

Nucleic Acid ◽

Nuclear Localization ◽

Nuclear Import ◽

Nuclear Localization Signal ◽

Peptide Nucleic Acid ◽

Nucleic Acid Binding ◽

Localization Signal ◽

Targeted Microbubbles ◽

Exogenous Genes

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Ultrasound-targeted microbubbles combined with a peptide nucleic acid binding nuclear localization signal mediate transfection of exogenous genes by improving cytoplasmic and nuclear import

Molecular Medicine Reports ◽

10.3892/mmr.2017.7681 ◽

2017 ◽

Vol 16 (6) ◽

pp. 8819-8825 ◽

Author(s):

Nan Jiang ◽

Qian Chen ◽

Sheng Cao ◽

Bo Hu ◽

Yi-Jia Wang ◽

...

Keyword(s):

Nucleic Acid ◽

Nuclear Localization ◽

Nuclear Import ◽

Nuclear Localization Signal ◽

Peptide Nucleic Acid ◽

Nucleic Acid Binding ◽

Localization Signal ◽

Targeted Microbubbles ◽

Exogenous Genes

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Combining single-molecule manipulation and peptide nucleic acid binding studies for unraveling how RNA structures regulate ribosomal frameshifting and alternative splicing

10.32657/10220/48612 ◽

2019 ◽

Author(s):

Lixia Yang

Keyword(s):

Alternative Splicing ◽

Nucleic Acid ◽

Single Molecule ◽

Peptide Nucleic Acid ◽

Nucleic Acid Binding ◽

Rna Structures ◽

Binding Studies ◽

Ribosomal Frameshifting ◽

Single Molecule Manipulation

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Snapshot blotting: The transfer of nucleic acids and nucleoprotein complexes from electrophoresis gels to EM grids

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100124215 ◽

1992 ◽

Vol 50 (1) ◽

pp. 762-763

Author(s):

Stephen D. Jett

Keyword(s):

Nucleic Acid ◽

Nucleic Acids ◽

Nucleic Acid Binding ◽

Mobility Shift ◽

Carbon Coated ◽

Nucleoprotein Complexes ◽

Mobility Shift Assay ◽

Protein Nucleic Acid ◽

Gel Mobility Shift ◽

Nucleic Acid Interactions

The electrophoresis gel mobility shift assay is a popular method for the study of protein-nucleic acid interactions. The binding of proteins to DNA is characterized by a reduction in the electrophoretic mobility of the nucleic acid. Binding affinity, stoichiometry, and kinetics can be obtained from such assays; however, it is often desirable to image the various species in the gel bands using TEM. Present methods for isolation of nucleoproteins from gel bands are inefficient and often destroy the native structure of the complexes. We have developed a technique, called “snapshot blotting,” by which nucleic acids and nucleoprotein complexes in electrophoresis gels can be electrophoretically transferred directly onto carbon-coated grids for TEM imaging.

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Molecular insights on the dynamic stability of peptide nucleic acid functionalized carbon and boron nitride nanotubes

Physical Chemistry Chemical Physics ◽

10.1039/d0cp05759b ◽

2021 ◽

Vol 23 (1) ◽

pp. 219-228

Author(s):

Nabanita Saikia ◽

Mohamed Taha ◽

Ravindra Pandey

Keyword(s):

Nucleic Acid ◽

Boron Nitride ◽

Nucleic Acids ◽

Dynamic Stability ◽

Peptide Nucleic Acid ◽

Rational Design ◽

Peptide Nucleic Acids ◽

Boron Nitride Nanotubes ◽

Molecular Hybrids ◽

Single Wall Nanotubes

The rational design of self-assembled nanobio-molecular hybrids of peptide nucleic acids with single-wall nanotubes rely on understanding how biomolecules recognize and mediate intermolecular interactions with the nanomaterial's surface.

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