Evidence for a Functional Role of the Dynamics of Glycine-121 ofEscherichia coliDihydrofolate Reductase Obtained from Kinetic Analysis of a Site-Directed Mutant†

Biochemistry ◽  
1997 ◽  
Vol 36 (50) ◽  
pp. 15792-15800 ◽  
Author(s):  
Craig E. Cameron ◽  
Stephen J. Benkovic
Keyword(s):  
Kinetic Analysis ◽  
Functional Role ◽  
A Site

What makes social Q&A site use enjoyable? The role of using modes and intrinsic needs satisfaction.

2019 ◽  
Vol 8 (3) ◽  
pp. 190-197
Author(s):  
Di Cui ◽  
Qihao Ji
Keyword(s):  
Needs Satisfaction ◽  
Site Use ◽  
A Site

A functional role of nuclear polyamines in murine brain

2000 ◽  
Vol 38 ◽  
pp. S66
Author(s):  
K Aramachi
Keyword(s):  
Functional Role ◽  
Murine Brain

Expression and functional role of c-Kit and erbB2 in human hepatoblastoma.

2009 ◽  
Vol 221 (03) ◽  
Author(s):  
B Steiger ◽  
I Leuschner ◽  
D Denkhaus ◽  
D von Schweinitz ◽  
T Pietsch
Keyword(s):  
Functional Role

A functional role of Macrophage Migration Inhibitory Factor (MIF) for liver steatosis in mice by activation of AMP kinase

2012 ◽  
Vol 50 (01) ◽  
Author(s):  
D Heinrichs ◽  
M Knauel ◽  
A Nellen ◽  
P Schmitz ◽  
C Trautwein ◽  
...  
Keyword(s):  
Migration Inhibitory Factor ◽  
Functional Role ◽  
Macrophage Migration Inhibitory Factor ◽  
Liver Steatosis ◽  
Inhibitory Factor ◽  
Macrophage Migration ◽  
Amp Kinase

Presence and functional role of KiSS/KiSS-R system in pancreatic neuroendocrine tumors (panNETs) and its relationship with clinical features and tumor behavior

2018 ◽  
Author(s):  
Emilia Alors-Perez ◽  
Sergio Pedraza-Arevalo ◽  
Aura Herrera-Martinez ◽  
Angel J Diaz-Perez ◽  
Teresa Caro ◽  
...  
Keyword(s):  
Clinical Features ◽  
Neuroendocrine Tumors ◽  
Functional Role ◽  
Pancreatic Neuroendocrine Tumors

Defensive Role of Plant-Derived Secondary Metabolites: Indole and Its’ Derivatives

2020 ◽  
Vol 9 (2) ◽  
pp. 78-88
Author(s):  
Mulugeta Mulat ◽  
Raksha Anand ◽  
Fazlurrahman Khan
Keyword(s):  
Biofilm Formation ◽  
Growth And Development ◽  
Functional Role ◽  
Plant Pathogens ◽  
Bacterial Species ◽  
Indole Derivatives ◽  
Resistance Level ◽  
Defensive Role ◽  
Insect Attack

The diversity of indole concerning its production and functional role has increased in both prokaryotic and eukaryotic systems. The bacterial species produce indole and use it as a signaling molecule at interspecies, intraspecies, and even at an interkingdom level for controlling the capability of drug resistance, level of virulence, and biofilm formation. Numerous indole derivatives have been found to play an important role in the different systems and are reported to occur in various bacteria, plants, human, and plant pathogens. Indole and its derivatives have been recognized for a defensive role against pests and insects in the plant kingdom. These indole derivatives are produced as a result of the breakdown of glucosinolate products at the time of insect attack or physical damages. Apart from the defensive role of these products, in plants, they also exhibit several other secondary responses that may contribute directly or indirectly to the growth and development. The present review summarized recent signs of progress on the functional properties of indole and its derivatives in different plant systems. The molecular mechanism involved in the defensive role played by indole as well as its’ derivative in the plants has also been explained. Furthermore, the perspectives of indole and its derivatives (natural or synthetic) in understanding the involvement of these compounds in diverse plants have also been discussed.

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