Nirogy debuts to drug transporter proteins

2021 ◽  
Vol 99 (4) ◽  
pp. 11-11
Author(s):  
Ryan Cross
2017 ◽  
Vol 7 (4) ◽  
pp. 501-505 ◽  
Author(s):  
Naina Mohamed Pakkir Maideen ◽  
Abdurazak Jumale ◽  
Rajkapoor Balasubramaniam

1992 ◽  
Vol 206 (1-2) ◽  
pp. 25-32 ◽  
Author(s):  
R.J. Scheper ◽  
H.J. Broxterman ◽  
G.L. Scheffer ◽  
C.J.L.M. Meijer ◽  
H.M. Pinedo

2021 ◽  
Vol 160 ◽  
pp. 103281
Author(s):  
Flavia Cunha Vasconcelos ◽  
Paloma Silva de Souza ◽  
Thaís Hancio ◽  
Fernanda Costas Casal de Faria ◽  
Raquel Ciuvalschi Maia

2004 ◽  
Vol 48 (12) ◽  
pp. 4869-4872 ◽  
Author(s):  
Julie Millet ◽  
Sandrine Alibert ◽  
Marylin Torrentino-Madamet ◽  
Christophe Rogier ◽  
Christiane Santelli-Rouvier ◽  
...  

ABSTRACT BG958 reverses resistance in chloroquine-resistant isolates from different countries. Five mutations in the Plasmodium falciparum crt (pfcrt) gene resulting in the amino acid changes K76T, M74I, N75E, A220S, and R371I are systematically identified in resistance-reversed Asian, African, and Brazilian parasites which possess the pfcrt (CIET) haplotype. In combination with BG958, the activity of chloroquine is increased in parasites with the N86Y mutation in pfmdr1.


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