Gradualism: A Method for Primary Instruction on Spectroscopic Analysis in Introductory Organic Chemistry

1999 ◽  
Vol 76 (9) ◽  
pp. 1297 ◽  
Author(s):  
Christopher W. Alexander ◽  
Gary L. Asleson ◽  
Charles F. Beam ◽  
Marion T. Doig ◽  
Frederick J. Heldrich ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Spectroscopic Analysis

A Greener Approach for Synthesis of Quinoline-3-carboxylate Building Block and their Biological Screening

2021 ◽  
Vol 6 (4) ◽  
pp. 259-263
Author(s):  
Kapilkumar Galachar ◽  
Ashokbhai R. Rathod ◽  
Chandankumar Pashavan ◽  
Yogesh Naliapara ◽  
Vipul Kataria ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Multicomponent Reactions ◽  
Spectroscopic Analysis ◽  
Ammonium Acetate ◽  
Biological Evaluation ◽  
Quinoline Derivatives ◽  
Industrial Chemistry ◽  
Biological Screening ◽  
A Value ◽  
Clean Synthesis

The analogs of nitrogen-based heterocycles occupy an exclusive position as a value of more than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. Among many N-containing heterocycles, quinolines have become important due to their variety of applications in medicinal, synthetic organic chemistry as well as in the field of industrial chemistry. Present work gives information about the green and clean synthesis using multicomponent reactions (MCRs) methods and L-proline and ammonium acetate as a catalyst for the synthesis of quinoline derivatives. Synthesized quinoline derivatives undergo spectroscopic analysis and their biological evaluation.

Discovery-Based Bromination of Alcohols: An Organic Chemistry Experiment Supporting Spectroscopic Analysis and Mechanistic Reasoning

2021 ◽  
Author(s):  
Matthew C. O’Reilly ◽  
Stacey A. Stoffregen ◽  
Karl P. Peterson ◽  
Mitchell P. Maddox ◽  
Cordell Schrank
Keyword(s):  
Organic Chemistry ◽  
Spectroscopic Analysis ◽  
Mechanistic Reasoning ◽  
Chemistry Experiment

Characterization of Chemical Impurities in Glutaraldehyde

1975 ◽  
Vol 33 ◽  
pp. 620-621
Author(s):  
B. J. Grenon ◽  
A. J. Tousimis
Keyword(s):  
Glutaric Acid ◽  
Spectroscopic Analysis ◽  
Aldol Condensation ◽  
Condensation Product ◽  
Amorphous Solid ◽  
Water Soluble ◽  
Impurity Component ◽  
Chemical Impurities ◽  
Soluble Liquid

Ever since the introduction of glutaraldehyde as a fixative in electron microscopy of biological specimens, the identification of impurities and consequently their effects on biologic ultrastructure have been under investigation. Several reports postulate that the impurities of glutaraldehyde, used as a fixative, are glutaric acid, glutaraldehyde polymer, acrolein and glutaraldoxime.Analysis of commercially available biological or technical grade glutaraldehyde revealed two major impurity components, none of which has been reported. The first compound is a colorless, water-soluble liquid with a boiling point of 42°C at 16 mm. Utilizing Nuclear Magnetic Resonance (NMR) spectroscopic analysis, this compound has been identified to be — dihydro-2-ethoxy 2H-pyran. This impurity component of the glutaraldehyde biological or technical grades has an UV absorption peak at 235nm. The second compound is a white amorphous solid which is insoluble in water and has a melting point of 80-82°C. Initial chemical analysis indicates that this compound is an aldol condensation product(s) of glutaraldehyde.

Elemental analysis of human erythrocytes

1989 ◽  
Vol 47 ◽  
pp. 242-243
Author(s):  
S. A. Livesey ◽  
A. A. del Campo ◽  
E. S. Griffey ◽  
D. Ohlmer ◽  
T. Schifani ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Elemental Analysis ◽  
Human Erythrocyte ◽  
Spectroscopic Analysis ◽  
Model System ◽  
Human Erythrocytes ◽  
List Type ◽  
Chemical Fixation ◽  
Ethanol Dehydration ◽  
Lowicryl K4m

The aim of this study is to compare methods of sample preparation for elemental analysis. The model system which is used is the human erythrocyte. Energy dispersive spectroscopic analysis has been previously reported for cryofixed and cryosectioned erythrocytes. Such work represents the reference point for this study. The use of plastic embedded samples for elemental analysis has also been documented. The work which is presented here is based on human erythrocytes which have been either chemically fixed and embedded or cryofixed and subsequently processed by a variety of techniques which culminated in plastic embedded samples.Heparinized and washed erythrocytes were prepared by the following methods for this study :(1). Chemical fixation in 4% paraformaldehyde/0.25% glutaraldehyde/0.2 M sucrose in 0.1 M Na cacodylate, pH 7.3 for 30 min, followed by ethanol dehydration, infiltration and embedding in Lowicryl K4M at -20° C.

Achievement Emotions Questionnaire--Organic Chemistry

2019 ◽  
Author(s):  
Jeffrey R. Raker ◽  
Rebecca E. Gibbons ◽  
Daniel Cruz-Ramírez de Arellano
Keyword(s):  
Organic Chemistry ◽  
Achievement Emotions
Sign in / Sign up

Export Citation Format

Share Document