Synthesis of Dual Thermosensitive and pH-Sensitive Hollow Nanospheres Based on Poly(acrylic acid-b-2-hydroxyethyl methacrylate) via an Atom Transfer Reversible Addition–Fragmentation Radical Process

2014 ◽  
Vol 53 (19) ◽  
pp. 8079-8086 ◽  
Author(s):  
Pourya Panahian ◽  
Mehdi Salami-Kalajahi ◽  
Mahdi Salami Hosseini
Keyword(s):  
Acrylic Acid ◽  
Ph Sensitive ◽  
Atom Transfer ◽  
Hydroxyethyl Methacrylate ◽  
Hollow Nanospheres ◽  
Radical Process ◽  
Reversible Addition ◽  
Poly Acrylic Acid

Development of a facile one-pot synthesis method for an ingestible pH sensitive actuator

MRS Advances ◽  
2019 ◽  
Vol 5 (17) ◽  
pp. 881-889
Author(s):  
Alex Keller ◽  
Holly Warren ◽  
Marc in het Panhuis
Keyword(s):  
Acrylic Acid ◽  
Calcium Hydroxide ◽  
Sodium Citrate ◽  
Synthesis Method ◽  
Gastric Fluid ◽  
Ph Sensitive ◽  
One Pot ◽  
Acidic Environments ◽  
Printed Materials ◽  
Poly Acrylic Acid

ABSTRACTEdible devices are an emergent technology and in this paper the simplicity and efficacy that poly(acrylic acid)/calcium hydroxide possess in creating a pH sensitive ingestible actuator which responds to acidic environments such as gastric fluid is demonstrated. It was found that poly(acrylic acid)/calcium hydroxide hydrogels exhibit reversible actuation upon submerging in 0.1 M sodium citrate for 2 hours. Our results show that these hydrogels can restore their compressive stress to 0.19 ± 0.06 MPa, swelling ratio to 26 ± 2 and volume to 56% ± 3% of its original volume. This work offers new possibilities for developments in a variety of fields such as drug delivery, 4D printed materials, soft robotics and edible devices.

Preparation and characterization of a novel pH-sensitive Salecan-g-poly(acrylic acid) hydrogel for controlled release of doxorubicin

2015 ◽  
Vol 3 (13) ◽  
pp. 2685-2697 ◽  
Author(s):  
Xinyu Hu ◽  
Wei Wei ◽  
Xiaoliang Qi ◽  
Hao Yu ◽  
Liandong Feng ◽  
...  
Keyword(s):  
Controlled Release ◽  
Acrylic Acid ◽  
Ph Sensitive ◽  
Swelling Behaviour ◽  
Poly Acrylic Acid

The pH-sensitive swelling behaviour and DOX release of Salecan-g-PAA hydrogels are discussed.

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