Development and Application of a Novel Semi-quantification Approach in LC-QToF-MS Analysis of Natural Products

2021 ◽  
Author(s):  
Reza Aalizadeh ◽  
Anthi Panara ◽  
Nikolaos S. Thomaidis
Keyword(s):  
Natural Products ◽  
Ms Analysis

scholarly journals Pulchranins B and C, New Acyclic Guanidine Alkaloids from the Far-Eastern Marine Sponge Monanchora Pulchra

2013 ◽  
Vol 8 (9) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Tatyana N. Makarieva ◽  
Ekaterina K. Ogurtsova ◽  
Yuliya V. Korolkova ◽  
Yaroslav A. Andreev ◽  
Irina V. Mosharova ◽  
...  
Keyword(s):  
Natural Products ◽  
Marine Sponge ◽  
Marine Natural Products ◽  
Ms Analysis ◽  
Guanidine Alkaloids ◽  
Far Eastern

New marine natural products, pulchranins B and C (2 and 3), were isolated from the marine sponge Monanchora pulchra and their structures were established using NMR and MS analysis. Compounds 2 and 3 were moderately active as inhibitors of TRPV1 (EC50 value of 95 and 183 μM, respectively) and less potent against TRPV3 and TRPA1 receptors.

scholarly journals Gramine-derived Bromo-alkaloids Activating NF-κB-dependent Transcription from the Marine Hydroid Abietinaria abietina

2016 ◽  
Vol 11 (9) ◽  
pp. 1934578X1601100
Author(s):  
Alla G. Guzii ◽  
Tatyana N. Makarieva ◽  
Sergey N. Fedorov ◽  
Vladimir A. Denisenko ◽  
Pavel S. Dmitrenok ◽  
...  
Keyword(s):  
Natural Products ◽  
Transcriptional Activity ◽  
Ms Analysis

Two new natural products, 6-bromogramine (1) and bis-6-bromogramine (2) were isolated from the marine hydroid Abietinaria abietina and their structures were established using NMR and MS analysis. Compounds 1 and 2 activate NF-κB-dependent transcriptional activity in JB6 Cl 41 NF-κB cells at 1.6 μM concentrations.

Identification of Tropane Alkaloids in Hairy Root Cultures of Hyoscyamus albus

1991 ◽  
Vol 46 (7-8) ◽  
pp. 519-521 ◽  
Author(s):  
Katja Doerk ◽  
Ludger Witte ◽  
A. Wilhelm Alfermann
Keyword(s):  
Natural Products ◽  
Hairy Root ◽  
Hairy Roots ◽  
Tropane Alkaloids ◽  
Hairy Root Cultures ◽  
Root Cultures ◽  
Ms Analysis ◽  
Trace Compounds ◽  
Solanaceous Plants ◽  
Hyoscyamus Albus

Abstract Tropane alkaloids are typical natural products of solanaceous plants. The patterns of these alkaloids from hairy roots of Hyoscyamus albus were determined by GC-MS analysis. 18 alka-loidal compounds were detected, six of them only in trace amounts. Some of these alkaloids, namely hygrine, 3a-acetoxytropane, 3 β-acetoxytropane and 6-hydroxylittorine as well as the trace compounds N-methylpyrrolidinylhygrine, phenylacetoxytropane and two isomers of feruloyloxytropane were not previously reported to be components of this species. The major compounds formed were found to be hyoscyamine and littorine.

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