Nonprenylated Rotenoids, a New Class of Potent Breast Cancer Resistance Protein Inhibitors

2007 ◽  
Vol 50 (8) ◽  
pp. 1933-1938 ◽  
Author(s):  
Abdelhakim Ahmed-Belkacem ◽  
Sira Macalou ◽  
Francesca Borrelli ◽  
Raffaele Capasso ◽  
Ernesto Fattorusso ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Resistance Protein ◽  
Cancer Resistance ◽  
Protein Inhibitors ◽  
New Class ◽  
Resistance Protein

Acryloylphenylcarboxamides: A New Class of Breast Cancer Resistance Protein (ABCG2) Modulators

ChemMedChem ◽  
2016 ◽  
Vol 11 (21) ◽  
pp. 2422-2435 ◽  
Author(s):  
Stefanie Kraege ◽  
Sebastian C. Köhler ◽  
Michael Wiese
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Resistance Protein ◽  
Cancer Resistance ◽  
New Class ◽  
Resistance Protein

scholarly journals Marine Natural Products as Breast Cancer Resistance Protein Inhibitors

Marine Drugs ◽  
2015 ◽  
Vol 13 (4) ◽  
pp. 2010-2029 ◽  
Author(s):  
Lilia Cherigo ◽  
Dioxelis Lopez ◽  
Sergio Martinez-Luis
Keyword(s):  
Breast Cancer ◽  
Natural Products ◽  
Marine Natural Products ◽  
Breast Cancer Resistance Protein ◽  
Cancer Resistance ◽  
Protein Inhibitors ◽  
Resistance Protein

scholarly journals PHENOLIC COMPOUNDS FROM STEM OF BOERHAVIA ERECTA L. GROWING IN VIETNAM

2011 ◽  
Vol 14 (2) ◽  
pp. 58-65
Author(s):  
Lien Thi My Do ◽  
Dung Thi My Nguyen ◽  
Phung Kim Phi Nguyen
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Resistance Protein ◽  
2D Nmr ◽  
Hepatoprotective Activity ◽  
Cancer Resistance ◽  
New Class ◽  
Nmr Data ◽  
Medicinal Properties ◽  
Resistance Protein ◽  
First Time

Plants of Boerhavia genus (Nyctaginaceae family) are known to have medicinal properties as antidiabetic, immunomodulatory effect, anticonvulsant, antistress, adaptogenic, hepatoprotective activity. Rotenoids in plants of this genus are reported as a new class of potent breast cancer resistance protein inhibitors.[5] Boerhavia erecta L. was used in traditional African medicine but there are still no scientific research in Vietnam where it is widely grown. In this paper, we report the isolation of four compounds: 2,6-dimethoxybenzoquinone (1), (+)-catechin (2), isorhamnetin 3-O-β- D-glucopyranoside (3) and rutin (4). The structure of these compounds were determined through the interpretation of their MS and 1D, 2D-NMR data. This is the first time that these compounds are isolated from Boerhavia erecta L.

Symmetric Bis-chalcones as a New Type of Breast Cancer Resistance Protein Inhibitors with a Mechanism Different from That of Chromones

2014 ◽  
Vol 57 (7) ◽  
pp. 2930-2941 ◽  
Author(s):  
Evelyn Winter ◽  
Patrícia Devantier Neuenfeldt ◽  
Louise Domeneghini Chiaradia-Delatorre ◽  
Charlotte Gauthier ◽  
Rosendo Augusto Yunes ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Resistance Protein ◽  
Cancer Resistance ◽  
Protein Inhibitors ◽  
New Type ◽  
Resistance Protein
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