Synthesis, Activity, and Structure−Activity Relationship Studies of Novel Cationic Lipids for DNA Transfer

1998 ◽  
Vol 41 (2) ◽  
pp. 224-235 ◽  
Author(s):  
Gerardo Byk ◽  
Catherine Dubertret ◽  
Virginie Escriou ◽  
Marc Frederic ◽  
Gabrielle Jaslin ◽  
...  
RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18681-18689 ◽  
Author(s):  
De-Chun Chang ◽  
Yi-Mei Zhang ◽  
Ji Zhang ◽  
Yan-Hong Liu ◽  
Xiao-Qi Yu

The structure–activity relationships of cyclen-based cationic lipids as non-viral gene delivery vectors were studied and clarified.


2015 ◽  
Vol 13 (2) ◽  
pp. 620-630 ◽  
Author(s):  
Zheng Huang ◽  
Yan-Hong Liu ◽  
Yi-Mei Zhang ◽  
Ji Zhang ◽  
Qiang Liu ◽  
...  

Imidazole-functionalized cationic lipids with a cyclen headgroup were synthesized, and the structure–activity relationship in gene delivery mediated by these lipids was discussed.


RSC Advances ◽  
2015 ◽  
Vol 5 (73) ◽  
pp. 59417-59427 ◽  
Author(s):  
Hai-Jiao Wang ◽  
Xi He ◽  
Yang Zhang ◽  
Ji Zhang ◽  
Yan-Hong Liu ◽  
...  

The gene transfection abilities and structure–activity relationship of the newly designed hydroxyl-containing cationic lipids were studied in detail.


MedChemComm ◽  
2013 ◽  
Vol 4 (10) ◽  
pp. 1354 ◽  
Author(s):  
Lisheng Deng ◽  
Zana Muhaxhiri ◽  
Mary K. Estes ◽  
Timothy Palzkill ◽  
B. V. Venkataram Prasad ◽  
...  

RSC Advances ◽  
2014 ◽  
Vol 4 (83) ◽  
pp. 44261-44268 ◽  
Author(s):  
Yi-Mei Zhang ◽  
Yan-Hong Liu ◽  
Ji Zhang ◽  
Qiang Liu ◽  
Zheng Huang ◽  
...  

Eleven Gemini cationic lipids and one mono counterpart were synthesized, and their structure–activity relationship as non-viral gene vectors was studied.


2014 ◽  
Vol 2 (10) ◽  
pp. 1460-1470 ◽  
Author(s):  
Hai-Jiao Wang ◽  
Yan-Hong Liu ◽  
Ji Zhang ◽  
Yang Zhang ◽  
Yan Xia ◽  
...  

The gene transfection abilities and structure–activity relationship of newly designed cationic lipids were studied in detail.


Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
MA Brenzan ◽  
CV Nakamura ◽  
BPD Filho ◽  
T Ueda-Nakamura ◽  
MCM Young ◽  
...  

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