Computational and Experimental Study of the Cyclic Voltammetry Response of Partially Blocked Electrodes. Part 1. Nonoverlapping, Uniformly Distributed Blocking Systems

Radiosensitizers are drugs that make cancer cells more sensitive to radiation therapy. The cytotoxic properties of such compounds are due to the fact that in the cell these compounds undergo one-electron reduction to generate radical anions. Therefore, their theoretical and/or experimental study is of high interest. To determine the correlation between reduction potential determined by cyclic voltammetry measurements and some physicochemical properties of selected radiosensitizers theoretical calculations of electron affinities based on the DFT method with B3LYP functional at the level of 6-311++G** basis set in vacuum were utilized. Very good correlation was found between electron affinities of radiosensitizers and their reduction potential and so called E71 potential that account for the energy necessary to transfer the first electron to an electroactive group at pH 7 in aqueous medium to form a radical anion.

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Numerical simulation of partially blocked electrodes under cyclic voltammetry conditions: influence of the block unit geometry on the global electrochemical properties

Journal of Electroanalytical Chemistry ◽

10.1016/j.jelechem.2004.11.033 ◽

2005 ◽

Vol 577 (2) ◽

pp. 211-221 ◽

Cited By ~ 25

Author(s):

François G. Chevallier ◽

Trevor J. Davies ◽

Oleksiy V. Klymenko ◽

Li Jiang ◽

Timothy G.J. Jones ◽

...

Keyword(s):

Numerical Simulation ◽

Cyclic Voltammetry ◽

Electrochemical Properties ◽

Partially Blocked Electrodes

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Cyclic voltammetry at shallow recessed microdisc electrode: Theoretical and experimental study

Journal of Electroanalytical Chemistry ◽

10.1016/j.jelechem.2009.01.030 ◽

2009 ◽

Vol 629 (1-2) ◽

pp. 180-184 ◽

Cited By ~ 17

Author(s):

Jidong Guo ◽

Ernő Lindner

Keyword(s):

Experimental Study ◽

Cyclic Voltammetry

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The electron as a probe to measure the thickness distributions of electroactive films

Chemical Science ◽

10.1039/c9sc03653a ◽

2020 ◽

Vol 11 (4) ◽

pp. 937-946 ◽

Cited By ~ 2

Author(s):

Darren Buesen ◽

Huaiguang Li ◽

Nicolas Plumeré

Keyword(s):

Experimental Study ◽

Cyclic Voltammetry ◽

Theoretical Model ◽

Electroactive Films ◽

Cyclic Voltammetry Data

A theoretical model combined to an experimental study shows that the morphology of electron conducting films can be quantified directly from the analysis of cyclic voltammetry data.

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Experimental study on the restoration from a tilt-azimuth series for improvement in resolution

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010013955x ◽

1995 ◽

Vol 53 ◽

pp. 636-637

Author(s):

Norio Baba ◽

Norihiko Ichise ◽

Syunya Watanabe

Keyword(s):

Experimental Study ◽

Spherical Aberration ◽

Incident Beam ◽

Optical Parameters ◽

Beam Tilting ◽

Illumination Method ◽

Restoration Method ◽

Illumination Mode

The tilted beam illumination method is used to improve the resolution comparing with the axial illumination mode. Using this advantage, a restoration method of several tilted beam images covering the full azimuthal range was proposed by Saxton, and experimentally examined. To make this technique more reliable it seems that some practical problems still remain. In this report the restoration was attempted and the problems were considered. In our study, four problems were pointed out for the experiment of the restoration. (1) Accurate beam tilt adjustment to fit the incident beam to the coma-free axis for the symmetrical beam tilting over the full azimuthal range. (2) Accurate measurements of the optical parameters which are necessary to design the restoration filter. Even if the spherical aberration coefficient Cs is known with accuracy and the axial astigmatism is sufficiently compensated, at least the defocus value must be measured. (3) Accurate alignment of the tilt-azimuth series images.

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