MD and QM/MM Studies on Long-Chain l-α-Hydroxy Acid Oxidase: Substrate Binding Features and Oxidation Mechanism

2014 ◽  
Vol 118 (20) ◽  
pp. 5406-5417 ◽  
Author(s):  
Yang Cao ◽  
Shuang Han ◽  
Lushan Yu ◽  
Haiyan Qian ◽  
Jian-Zhong Chen
Keyword(s):  
Hydroxy Acid ◽  
Substrate Binding ◽  
Oxidation Mechanism ◽  
Acid Oxidase ◽  
Long Chain

Crystal Structure Analysis of Recombinant Rat Kidney Long Chain Hydroxy Acid Oxidase†,‡

Biochemistry ◽  
2005 ◽  
Vol 44 (5) ◽  
pp. 1521-1531 ◽  
Author(s):  
Louise M. Cunane ◽  
John D. Barton ◽  
Zhi-wei Chen ◽  
K. H. Diêp Lê ◽  
David Amar ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Structure Analysis ◽  
Hydroxy Acid ◽  
Rat Kidney ◽  
Crystal Structure Analysis ◽  
Acid Oxidase ◽  
Long Chain

Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain l-2-hydroxy acid oxidase

2012 ◽  
Vol 22 (13) ◽  
pp. 4341-4347 ◽  
Author(s):  
Dinesh A. Barawkar ◽  
Anish Bandyopadhyay ◽  
Anil Deshpande ◽  
Summon Koul ◽  
Sachin Kandalkar ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Hydroxy Acid ◽  
Acid Oxidase ◽  
Long Chain

scholarly journals Potent and Selective Inhibitors of Long Chain l-2-Hydroxy Acid Oxidase Reduced Blood Pressure in DOCA Salt-Treated Rats

2011 ◽  
Vol 2 (12) ◽  
pp. 919-923 ◽  
Author(s):  
Dinesh A. Barawkar ◽  
Ashwin Meru ◽  
Anish Bandyopadhyay ◽  
Abir Banerjee ◽  
Anil M. Deshpande ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Hydroxy Acid ◽  
Acid Oxidase ◽  
Selective Inhibitors ◽  
Long Chain

scholarly journals Methylguanidine Synthase from Rat Kidney Is Identical to Long-Chain L-2-Hydroxy Acid Oxidase

Nephron ◽  
1994 ◽  
Vol 68 (2) ◽  
pp. 279-279 ◽  
Author(s):  
Hisashi Ozasa ◽  
Saburo Horikawa ◽  
Kazuo Ota
Keyword(s):  
Hydroxy Acid ◽  
Rat Kidney ◽  
Acid Oxidase ◽  
Long Chain
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