Enhanced Bioavailability of a Poorly Water-Soluble Weakly Basic Compound Using a Combination Approach of Solubilization Agents and Precipitation Inhibitors: A Case Study

2012 ◽  
Vol 9 (5) ◽  
pp. 1100-1108 ◽  
Author(s):  
Shu Li ◽  
Crystal Pollock-Dove ◽  
Liang C. Dong ◽  
Jing Chen ◽  
Abla A. Creasey ◽  
...  
Keyword(s):  
Water Soluble ◽  
Precipitation Inhibitors ◽  
Poorly Water Soluble ◽  
Combination Approach

Increasing bioavailability of very poorly water-soluble compounds. A case study of an anti-tumor drug, soloxolon methyl

2019 ◽  
Vol 49 ◽  
pp. 35-42 ◽  
Author(s):  
A.G. Ogienko ◽  
A.V. Markov ◽  
A.V. Sen'kova ◽  
E.B. Logashenko ◽  
O.V. Salomatina ◽  
...  
Keyword(s):  
Water Soluble ◽  
Poorly Water Soluble

Physical State of Poorly Water Soluble Therapeutic Molecules Loaded into SBA-15 Ordered Mesoporous Silica Carriers: A Case Study with Itraconazole and Ibuprofen

Langmuir ◽  
2008 ◽  
Vol 24 (16) ◽  
pp. 8651-8659 ◽  
Author(s):  
Randy Mellaerts ◽  
Jasper A. G. Jammaer ◽  
Michiel Van Speybroeck ◽  
Hong Chen ◽  
Jan Van Humbeeck ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Physical State ◽  
Water Soluble ◽  
Ordered Mesoporous Silica ◽  
Ordered Mesoporous ◽  
Therapeutic Molecules ◽  
Poorly Water Soluble

Self-assembling PEG-p(CL-co-TMC) copolymers for oral delivery of poorly water-soluble drugs: a case study with risperidone

2005 ◽  
Vol 102 (3) ◽  
pp. 657-668 ◽  
Author(s):  
Louisa Ould-Ouali ◽  
Marc Noppe ◽  
Xavier Langlois ◽  
Bart Willems ◽  
Paula Te Riele ◽  
...  
Keyword(s):  
Oral Delivery ◽  
Water Soluble ◽  
Poorly Water Soluble Drugs ◽  
Self Assembling ◽  
Water Soluble Drugs ◽  
Poorly Water Soluble

Cryosynthesis of Co-Crystals of Poorly Water-Soluble Pharmaceutical Compounds and Their Solid Dispersions with Polymers. The “Meloxicam–Succinic Acid” System as a Case Study

2018 ◽  
Vol 18 (12) ◽  
pp. 7401-7409 ◽  
Author(s):  
Andrey G. Ogienko ◽  
Svetlana A. Myz ◽  
Anna A. Ogienko ◽  
Andrey A. Nefedov ◽  
Andrey S. Stoporev ◽  
...  
Keyword(s):  
Succinic Acid ◽  
Solid Dispersions ◽  
Pharmaceutical Compounds ◽  
Water Soluble ◽  
Acid System ◽  
Poorly Water Soluble
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