scholarly journals Synthesis of Water-Soluble Poly(α-hydroxy acids) from Living Ring-Opening Polymerization of O-Benzyl-l-serine Carboxyanhydrides

2012 ◽  
Vol 1 (4) ◽  
pp. 441-444 ◽  
Author(s):  
Yanbing Lu ◽  
Lichen Yin ◽  
Yanfeng Zhang ◽  
Zhonghai Zhang ◽  
Yunxiang Xu ◽  
...  
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Water Soluble ◽  
Hydroxy Acids ◽  
Soluble Poly

scholarly journals Water-Soluble Poly(phosphonate)s via Living Ring-Opening Polymerization

2014 ◽  
Vol 3 (3) ◽  
pp. 244-248 ◽  
Author(s):  
Tobias Steinbach ◽  
Sandra Ritz ◽  
Frederik R. Wurm
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Water Soluble ◽  
Soluble Poly

scholarly journals Controlled Ring-Opening Polymerization of O-Carboxyanhydrides to Synthesize Functionalized Poly(α-Hydroxy Acids)

2021 ◽  
Vol 03 (01) ◽  
pp. 041-050
Author(s):  
Xiaoqian Wang ◽  
Ai Lin Chin ◽  
Rong Tong
Keyword(s):  
Biomedical Engineering ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Metal Catalyst ◽  
Hydroxy Acids ◽  
Controlled Polymerization ◽  
Biodegradable Polyesters ◽  
Recent Advances

Poly(α-hydroxy acids), as a family of biodegradable polyesters, are valuable materials due to their broad applications in packaging, agriculture, and biomedical engineering. Herein we highlight and explore recent advances of catalysts in controlled ring-opening polymerization of O-carboxyanhydrides towards functionalized poly(α-hydroxy acids), especially metal catalyst-mediated controlled polymerization. Limitations of current polymerization strategies of O-carboxyanhydrides are discussed.

Synthesis and Biomedical Applications of Functional Poly(α-hydroxy acids) via Ring-Opening Polymerization of O-Carboxyanhydrides

2015 ◽  
Vol 48 (7) ◽  
pp. 1777-1787 ◽  
Author(s):  
Qian Yin ◽  
Lichen Yin ◽  
Hua Wang ◽  
Jianjun Cheng
Keyword(s):  
Ring Opening ◽  
Biomedical Applications ◽  
Ring Opening Polymerization ◽  
Hydroxy Acids

Biodegradable Polymers Derived from Amino Acids for Biological Applications

2010 ◽  
Vol 76 ◽  
pp. 30-35 ◽  
Author(s):  
Naomi Cohen-Arazi ◽  
Ilanit Hagag ◽  
Michal Kolitz ◽  
Abraham J. Domb ◽  
Jeoshua Katzhendler
Keyword(s):  
Amino Acids ◽  
Molecular Weight ◽  
Ring Opening ◽  
Building Blocks ◽  
Ring Opening Polymerization ◽  
Microwave Assisted Synthesis ◽  
Hydroxy Acids ◽  
Natural Amino Acids ◽  
Direct Condensation ◽  
Positively Charged

Optically active α-hydroxy acids derived from amino acids have been synthesized and polymerized into new biodegradable polyesters. The variety of functional side chains enables the design of positively charged, negatively charged, hydrophobic and hydrophilic chiral building blocks or any combination of these constituents. Hydroxy acids of 15 natural amino acids were prepared with retention of configuration using a straightforward and reliable method of diazotization of α-amino acids. Polyesters were synthesized from these hydroxy acids by a number of methods: direct condensation in bulk, microwave assisted synthesis and ring opening polymerization. The molecular weight of the prepared polymers ranges between 2000 to 5000Da for the direct condensation and the microwave methods, whereas the ring opening polymerization results in high molecular weight polymers (20000 to 30000Da). The polymers were analyzed for their optical activity (Circular Dichroism Spectroscopy), thermal properties (DSC), solubility, molecular weight and polydispersity (GPC), and aqueous degradation. These polymers were tested for their compatibility to neuronal cells growth and differentiation.

Biological applications of water-soluble polypeptides with ordered secondary structures

2020 ◽  
Vol 8 (31) ◽  
pp. 6530-6547 ◽  
Author(s):  
Chenglong Ge ◽  
Huan Ye ◽  
Fan Wu ◽  
Junliang Zhu ◽  
Ziyuan Song ◽  
...  
Keyword(s):  
Ring Opening ◽  
Secondary Structures ◽  
Ring Opening Polymerization ◽  
Water Soluble ◽  
Biological Applications ◽  
Recent Advances

Herein, recent advances in the synthesis of the water-soluble polypeptides with ordered secondary structures via ring-opening polymerization of NCA/NTA and their biological applications are described.

Living Photolytic Ring-Opening Polymerization of Amino-Functionalized [1]Ferrocenophanes: Synthesis and Layer-by-Layer Self-Assembly of Well-Defined Water-Soluble Polyferrocenylsilane Polyelectrolytes

2007 ◽  
Vol 13 (33) ◽  
pp. 9372-9383 ◽  
Author(s):  
Zhuo Wang ◽  
Georgeta Masson ◽  
Frank C. Peiris ◽  
Geoffrey A. Ozin ◽  
Ian Manners
Keyword(s):  
Self Assembly ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Water Soluble ◽  
Layer By Layer

scholarly journals Dewar Heterocycles as Versatile Monomers for Ring-Opening Metathesis Polymerization

2020 ◽  
Author(s):  
Sepand Nistanaki ◽  
Hosea Nelson
Keyword(s):  
Ring Opening ◽  
Water Soluble ◽  
Ring Opening Metathesis Polymerization ◽  
Valence Isomerization ◽  
Metathesis Polymerization ◽  
Grubbs Catalysts ◽  
Amino Acid Polymers ◽  
Highly Strained ◽  
Acetylene Derivatives ◽  
Soluble Poly

We report the utility of readily available heterocycles as precursors to unique ring-opening metathesis polymerization (ROMP) monomers. Photochemical valence isomerization reactions of pyridones, dihydropyridines, and pyrones dearomatize the parent heterocycles to their highly strained Dewar isomers, which readily engage in controlled ROMP reactions using Grubbs catalysts. This strategy is used to access novel polymer backbones that contain strained β-lactam and azetidine cores, which can be further derivatized using post-polymerization chemistries. We demonstrate this through the synthesis of water-soluble β-amino acid polymers and soluble poly(acetylene) derivatives.

Carbon Nanotubes Containing Metal Nanoparticles-Graft-Hyperbranched Polyglycerols Nanocomposites

2011 ◽  
Vol 284-286 ◽  
pp. 360-364
Author(s):  
Jing Zhu ◽  
Yang Liu ◽  
Juan He ◽  
Hong Liang Wei ◽  
Hui Juan Chu
Keyword(s):  
Carbon Nanotubes ◽  
Silver Nanoparticles ◽  
Metal Nanoparticles ◽  
Potential Application ◽  
Ring Opening ◽  
Multiwall Carbon Nanotubes ◽  
Ring Opening Polymerization ◽  
Water Soluble ◽  
Multiwall Carbon

New water soluble multiwall carbon nanotubes (MWCNTs) containing silver nanoparticles-grafted-hyperbranched polyglycerols (HPG) nanocomposites were synthesized and characterized successfully. In this work, MWCNTs were opened using HNO3/H2SO4mixture and filled by metal nanoparticles such as silver nanoparticles through wet chemcial method. Then MWCNTs containing silver nanoparticles (MWCNTs(Ag)) were used as macroinitiator for ring opening polymerization of glycidol and MWCNTs(Ag)-g-HPG nanocomposites were obtained. Structure of nanocomposites was evaluated by TEM, TGA and spectroscopy methods. With the solubility of MWCNTs(Ag)-g-HPG greatly improved, the new nanocomposites exhibit potential application in biomedicine and nanomedicine.

Synthesis of water soluble and multi-responsive selenopolypeptides via ring-opening polymerization of N-carboxyanhydrides

2019 ◽  
Vol 55 (54) ◽  
pp. 7860-7863 ◽  
Author(s):  
Guangqi Wu ◽  
Chenglong Ge ◽  
Xingyi Liu ◽  
Shuo Wang ◽  
Letian Wang ◽  
...  
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Water Soluble

Synthesis of selenopolypeptides via ring opening polymerization of N-carboxyanhydrides.

A Water-Soluble Polycarbonate With Dimethylamino Pendant Groups Prepared by Enzyme-Catalyzed Ring-Opening Polymerization

2012 ◽  
Vol 33 (8) ◽  
pp. 693-697 ◽  
Author(s):  
Xiaojin Zhang ◽  
Mengmeng Cai ◽  
Zhenlin Zhong ◽  
Renxi Zhuo
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Water Soluble
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