Hyperbaric Oxygen Enhances the Expression of Prion Protein and Heat Shock Protein 70 in a Mouse Neuroblastoma Cell Line

2004 ◽  
Vol 24 (2) ◽  
pp. 257-268 ◽  
Author(s):  
Woei-Cherng Shyu ◽  
Shinn-Zong Lin ◽  
Keiichi Saeki ◽  
Astsutaka Kubosaki ◽  
Yoshitsugu Matsumoto ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Cell Line ◽  
Prion Protein ◽  
Hyperbaric Oxygen ◽  
Heat Shock Protein 70 ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Mouse Neuroblastoma Cell ◽  
Mouse Neuroblastoma

Clusterin Overexpression is Responsible for the Anti-apoptosis Effect in a Mouse Neuroblastoma Cell Line, B103

2003 ◽  
Vol 58 (1-2) ◽  
pp. 148-152 ◽  
Author(s):  
Kwan-Hee You ◽  
Young-Mi Ji ◽  
O-Yu Kwon
Keyword(s):  
Cell Line ◽  
Functional Role ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Apoptotic Index ◽  
Mouse Neuroblastoma Cell ◽  
Mouse Neuroblastoma ◽  
Apoptosis Inhibition ◽  
Clusterin Expression

The functional role of clusterin in apoptosis was examined using flow cytometry. Clusterin cDNA was transfected into the mouse neuroblastoma cell line, B103, in order to determine if clusterin overexpression inhibits apoptosis. The increased clusterin expression level in the B103 cells tended to suppress the apoptotic index. This suggests an association of clusterin gene expression with apoptosis inhibition. These results support the conclusion that clusterin expression in B103 cells has an antiapoptotic influence

scholarly journals miR-16-1 Promotes the Aberrantα-Synuclein Accumulation in Parkinson Disease via Targeting Heat Shock Protein 70

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Zhelin Zhang ◽  
Yan Cheng
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Parkinson Disease ◽  
Heat Shock Protein 70 ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Hsp70 Expression ◽  
Human Neuroblastoma Cell ◽  
Human Neuroblastoma ◽  
Human Neuroblastoma Cell Line

There is striking evidence that heat shock protein 70 (Hsp70) negatively regulatesα-synuclein aggregation, which plays a significant role in the formation and progression of Parkinson disease (PD). However, how the Hsp70 in neurons fails to prevent or even reverseα-synuclein aggregation and toxicity in PD still remains to be determined. In the present study, we constructed anα-synuclein-overexpressed human neuroblastoma cell line, SH-SY5Y-Syn, in which the blockage of Hsp70 promotedα-synuclein aggregation. And we also found that miR-16-1 downregulated Hsp70 and promotedα-synuclein aggregation in the SH-SY5Y-Syn cells. This study revealed a novel regulatory mechanism of Hsp70 expression, which might contribute to the PD development.

scholarly journals Assessing Proteinase K Resistance of Fish Prion Proteins in a Scrapie-Infected Mouse Neuroblastoma Cell Line

Viruses ◽  
2014 ◽  
Vol 6 (11) ◽  
pp. 4398-4421 ◽  
Author(s):  
Evgenia Salta ◽  
Eirini Kanata ◽  
Christos Ouzounis ◽  
Sabine Gilch ◽  
Hermann Schätzl ◽  
...  
Keyword(s):  
Cell Line ◽  
Infected Mouse ◽  
Prion Proteins ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Proteinase K ◽  
Mouse Neuroblastoma Cell ◽  
Mouse Neuroblastoma

Adriamycin promotes neurite outgrowth in the “neurite-minus” N1A-103 mouse neuroblastoma cell line

1992 ◽  
Vol 203 (1) ◽  
pp. 72-79 ◽  
Author(s):  
Jean Christophe Larcher ◽  
Laurence Cordeau-Lossouarn ◽  
Georges Romey ◽  
François Gros ◽  
Bernard Croizat ◽  
...  
Keyword(s):  
Neurite Outgrowth ◽  
Cell Line ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Mouse Neuroblastoma Cell ◽  
Mouse Neuroblastoma

Aluminum promotes neuronal plasticity events in a mouse neuroblastoma cell line

2001 ◽  
Vol 312 (1) ◽  
pp. 5-8 ◽  
Author(s):  
Vittorio Farina ◽  
Andrea Tapparo ◽  
Marco Zedda ◽  
Sergio Gadau ◽  
Gianluca Lepore
Keyword(s):  
Cell Line ◽  
Neuronal Plasticity ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Mouse Neuroblastoma Cell ◽  
Mouse Neuroblastoma
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