Confabulation: Gaining Understanding of Human Nature From Neurological Disorders

PsycCRITIQUES ◽  
2005 ◽  
Vol 50 (39) ◽  
Author(s):  
Josep M. Suelves
Author(s):  
Richard L. Klein ◽  
Åsa K. Thureson-Klein ◽  
Harihara M. Mehendale

KeponeR (decachlorooctahydro-1,3,4-metheno-2H-cyclobuta[cd]pentalen-2-one) is an insecticide effective against ants and roaches. It can cause severe toxicity in fishes, birds, rodents and man. Prominent effects include hepatic lipid deposition and hypertrophy, impairment of reproductive capacity and neurological disorders. Mitochondrial oligomycin-sensitive Mg2+-ATPase is also inhibited. The present study is a preliminary investigation of tissue ultrastructural changes accompanying physiological signs of acute toxicity, which after two days treatment include: pronounced hypersensitivity and tremor, various degrees of anorexia and adipsia, and decreased weight gain.Three different series of adult male Sprague-Dawley rats (Charles River or CD-I) were treated by intubation with Kepone in corn oil at a dose of 50 mg per kg for 3 successive days or at 200 ppm in food for 8 days. After ether anesthesia, rats were immediately perfused via a cannula in the left ventricle with 4% p-formaldehyde and 0.5% glutaraldehyde in Millonig's phosphate buffer at pH 7.2 for 20-30 min at 22°C.


2020 ◽  
Vol 31 (2) ◽  
pp. 62-68
Author(s):  
Sara E. Holm ◽  
Alexander Schmidt ◽  
Christoph J. Ploner

Abstract. Some people, although they are perfectly healthy and happy, cannot enjoy music. These individuals have musical anhedonia, a condition which can be congenital or may occur after focal brain damage. To date, only a few cases of acquired musical anhedonia have been reported in the literature with lesions of the temporo-parietal cortex being particularly important. Even less literature exists on congenital musical anhedonia, in which impaired connectivity of temporal brain regions with the Nucleus accumbens is implicated. Nonetheless, there is no precise information on the prevalence, causes or exact localization of both congenital and acquired musical anhedonia. However, the frequent involvement of temporo-parietal brain regions in neurological disorders such as stroke suggest the possibility of a high prevalence of this disorder, which leads to a considerable reduction in the quality of life.


2006 ◽  
Vol 61 (3) ◽  
pp. 258-259 ◽  
Author(s):  
Rolf Reber
Keyword(s):  

1997 ◽  
Vol 42 (6) ◽  
pp. 525-526
Author(s):  
Jack Martin
Keyword(s):  

1956 ◽  
Vol 1 (3) ◽  
pp. 90-90
Author(s):  
Albert S. Thompson
Keyword(s):  

1981 ◽  
Vol 26 (9) ◽  
pp. 686-687
Author(s):  
Marc Bekoff
Keyword(s):  

PsycCRITIQUES ◽  
2004 ◽  
Vol 49 (Supplement 1) ◽  
Author(s):  
Dario Maestripieri
Keyword(s):  

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