An early career perspective on working in a research-oriented medical center

2009 ◽  
Author(s):  
Jason C. Ong
Keyword(s):  
Medical Center ◽  
Early Career

scholarly journals First person – Victor Palacios

2021 ◽  
Vol 134 (7) ◽  
Keyword(s):  
Chromosome Segregation ◽  
Germ Cells ◽  
Medical Center ◽  
Early Career ◽  
First Person ◽  
University Of Texas ◽  
Early Career Researchers ◽  
The University ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Victor Palacios is first author on ‘Importin-9 regulates chromosome segregation and packaging in Drosophila germ cells’, published in JCS. Victor conducted his PhD research in the lab of Michael Buszczak at the University of Texas Southwestern Medical Center, Dallas, TX, where he investigated the essential role of Importin-9 in Drosophila fertility.

scholarly journals Publication rates of research projects of an internal funding program of a university medical center in Germany: A retrospective study (2004–2013)

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0243092
Author(s):  
Susanne Deutsch ◽  
Silke Reuter ◽  
Astrid Rose ◽  
René Tolba
Keyword(s):  
Research Funding ◽  
Medical Center ◽  
Early Career ◽  
Research Projects ◽  
Project Duration ◽  
Research Results ◽  
Publication Rates ◽  
Funding Program ◽  
Funding Programs ◽  
Internal Funding

Objectives Non-publication and publication bias are topics of considerable importance to the scientific community. These issues may limit progress toward the 3R principle for animal research, promote waste of public resources, and generate biased interpretations of clinical outcomes. To investigate current publishing practices and to gain some understanding of the extent to which research results are reported, we examined publication rates of research projects that were approved within an internal funding program of the Faculty of Medicine at a university medical center in Germany, which is exemplary for comparable research funding programs for the promotion of young researchers in Germany and Europe. Methods We analyzed the complete set (n = 363) of research projects that were supported by an internal funding program between 2004 and 2013. We divided the projects into four different proposal types that included those that required an ethics vote, those that included an animal proposal, those that included both requirements, and those that included neither requirement. Results We found that 65% of the internally funded research projects resulted in at least one peer-reviewed publication; this increased to 73% if other research contributions were considered, including abstracts, book and congress contributions, scientific posters, and presentations. There were no significant differences with respect to publication rates based on (a) the clinic/institute of the applicant, (b) project duration, (c) scope of funding or (d) proposal type. Conclusion To the best of our knowledge, this is the first study to explore publication rates associated with early-career medical research funding. As >70% of the projects ultimately generated some form of publication, the program was overall effective toward this goal; however, non-publication of research results is still prevalent. Further research will explore the reasons underlying non-publication. We hope to use these findings to develop strategies that encourage publication of research results.

scholarly journals First person – Lena Marie Westermann

2020 ◽  
Vol 13 (11) ◽  
pp. dmm047860
Keyword(s):  
Medical Center ◽  
Early Career ◽  
First Person ◽  
Lysosomal Storage ◽  
Joint Function ◽  
Cartilage Homeostasis ◽  
Early Career Researchers ◽  
Mucolipidosis Type ◽  
Storage Disorders ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers. Lena Marie Westermann is first author on ‘Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma’, published in DMM. Lena Marie is an MD student in the lab of Dr Sandra Pohl at University Medical Center Hamburg-Eppendorf, Hamburg, Germany, investigating bone and connective tissue phenotypes in lysosomal storage disorders.

scholarly journals Researchers’ Perceptions of a Responsible Research Climate: A Multi Focus Group Study

2020 ◽  
Vol 26 (6) ◽  
pp. 3017-3036
Author(s):  
Tamarinde Haven ◽  
H. Roeline Pasman ◽  
Guy Widdershoven ◽  
Lex Bouter ◽  
Joeri Tijdink
Keyword(s):  
Focus Group ◽  
Medical Center ◽  
Codes Of Conduct ◽  
Early Career ◽  
Focus Group Study ◽  
Group Discussions ◽  
Research Climate ◽  
Evaluation Policies ◽  
Group Interviews ◽  
Responsible Research

AbstractThe research climate plays a key role in fostering integrity in research. However, little is known about what constitutes a responsible research climate. We investigated academic researchers’ perceptions on this through focus group interviews. We recruited researchers from the Vrije Universiteit Amsterdam and the Amsterdam University Medical Center to participate in focus group discussions that consisted of researchers from similar academic ranks and disciplinary fields. We asked participants to reflect on the characteristics of a responsible research climate, the barriers they perceived and which interventions they thought fruitful to improve the research climate. Discussions were recorded and transcribed at verbatim. We used inductive content analysis to analyse the focus group transcripts. We conducted 12 focus groups with 61 researchers in total. We identified fair evaluation, openness, sufficient time, integrity, trust and freedom to be mentioned as important characteristics of a responsible research climate. Main perceived barriers were lack of support, unfair evaluation policies, normalization of overwork and insufficient supervision of early career researchers. Possible interventions suggested by the participants centered around improving support, discussing expectations and improving the quality of supervision. Some of the elements of a responsible research climate identified by participants are reflected in national and international codes of conduct, such as trust and openness. Although it may seem hard to change the research climate, we believe that the realisation that the research climate is suboptimal should provide the impetus for change informed by researchers’ experiences and opinions.

scholarly journals First person – Zakia Abdelhamed

2020 ◽  
Vol 13 (10) ◽  
pp. dmm047852
Keyword(s):  
Primary Ciliary Dyskinesia ◽  
Medical Center ◽  
Early Career ◽  
Human Condition ◽  
First Person ◽  
Hypomorphic Allele ◽  
Early Career Researchers ◽  
Research Associate ◽  
Ciliary Dyskinesia ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers. Zakia Abdelhamed is first author on ‘A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice’, published in DMM. Zakia is a research associate in the lab of Dr Rolf Stottmann at Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA, investigating animal models that recapitulate a human condition for understanding disease pathogenesis.

scholarly journals First person – Matthias Klose

2021 ◽  
Vol 134 (5) ◽  
Keyword(s):  
Borrelia Burgdorferi ◽  
Medical Center ◽  
Early Career ◽  
First Person ◽  
Human Macrophages ◽  
Early Career Researchers ◽  
Medical Microbiology ◽  
Intracellular Processing ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Matthias Klose is first author on ‘FIB-SEM-based analysis of Borrelia intracellular processing by human macrophages’, published in JCS. Matthias is a postdoc in the lab of Professor Stefan Linder at Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Eppendorf, Hamburg, Germany, investigating mechanisms that drive uptake and intracellular processing of Borrelia burgdorferi in primary human macrophages.

scholarly journals Evaluation of literature searching and article selection skills of an evidence-based practice team

2020 ◽  
Vol 108 (3) ◽  
Author(s):  
Emily Paige Jones ◽  
Emily A. Brennan ◽  
Amanda Davis
Keyword(s):  
Critical Appraisal ◽  
Evidence Based Practice ◽  
Medical Center ◽  
Academic Medical Center ◽  
Early Career ◽  
Work Flow ◽  
Evidence Based ◽  
Literature Searching ◽  
Literature Searches ◽  
Hospital Policies

Background: An evidence-based practice (EBP) team at an academic medical center supports the development of evidence-based hospital policies and protocols via “Evidence Briefs.” An early career librarian was added to the EBP team to meet increased requests for Evidence Briefs, which provided an opportunity to initiate a quality improvement (QI) analysis, improve work flow, and cross-train staff on literature searching and article selection skills.Case Presentation: This QI project evaluated literature searching and article selection skills of an early career librarian (less than 2 years’ experience), a mid-career librarian (more than 10 years’ experience), and a critical appraisal expert. This project examined 10 Evidence Brief requests completed within a 6-month period. Analysis of each individual’s performance of literature searching and article selection was completed for each Evidence Brief. Across all Evidence Brief requests, the mid-career librarian performed the most comprehensive literature searches and captured the highest number of articles that ultimately ended up being included in the Evidence Briefs (75%). The critical appraisal expert performed best on the article selection portion of the project and identified the highest number of relevant articles that were included in Evidence Briefs (74%).Conclusions: This project provided a formalized method of assessing the literature searching and article selection skills of each member of the EBP team. This project illustrated the skill level of each individual and led to improvements in the Evidence Brief request work flow.

scholarly journals First person – Ivo de Vos

Biology Open ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. bio057935
Keyword(s):  
Patient Care ◽  
Medical Center ◽  
Early Career ◽  
Clinical Genetics ◽  
First Person ◽  
Zebrafish Model ◽  
Common Skin ◽  
Skin Conditions ◽  
The University ◽  
Improving Patient Care

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Ivo de Vos is first author on ‘The novel zebrafish model pretzel demonstrates a central role for SH3PXD2B in defective collagen remodelling and fibrosis in Frank-Ter Haar syndrome’, published in BiO. Ivo conducted the research described in this article while a Research Fellow in Professor Maurice van Steensel's lab at the Skin Research Institute of Singapore (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore. He is now a Postgraduate House Officer in Clinical Genetics, currently working in patient care in the Department of Genetics, at the University Medical Center Groningen (UMCG), The Netherlands, investigating pathophysiological mechanisms underlying common skin conditions by studying rare genetic skin disorders, ultimately improving patient care.

scholarly journals First person – Frederike Riemslagh

2021 ◽  
Vol 14 (2) ◽  
pp. dmm048920
Keyword(s):  
Muscular Atrophy ◽  
Medical Center ◽  
Genetic Diseases ◽  
Early Career ◽  
Clinical Genetics ◽  
First Person ◽  
University Of Colorado ◽  
Erasmus Medical ◽  
The University ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers. Frederike Riemslagh is first author on ‘Inducible expression of human C9ORF72 36× G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice’, published in DMM. Frederike conducted the research described in this article while a PhD Candidate in Prof. Dr Rob Willemse's lab at Erasmus Medical Center, Department of Clinical Genetics, Rotterdam, The Netherlands. She is now a Postdoctoral Fellow in the lab of Dr Christian Mosimann at the University of Colorado, USA, investigating genetic diseases that affect the heart and brain.

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