The effect of therapists verbal activity level and specificity on patient productivity and speech disturbance in the initial interview.

1962 ◽  
Vol 26 (5) ◽  
pp. 489-489 ◽  
Author(s):  
Benjamin Pope ◽  
Aron W. Siegman
1973 ◽  
Vol 36 (3) ◽  
pp. 855-862 ◽  
Author(s):  
Bruce R. Fretz ◽  
Warren R. Johnson

Children participating in an 8-wk. clinic program focused on neuromotor perceptual training were compared with waiting-list controls for changes in physical activity level, verbal activity level, dependency, and aggression. Increased activity levels were expected in association with peers and clinic staff and decreased activity levels in association with a “mother-busy” situation. Of 15 significant effects obtained 12 were in the hypothesized directions. The results provide empirical evidence of previous anecdotal reports of the parents and teachers of the clinic participants.


2020 ◽  
Vol 64 (2) ◽  
pp. 325-336 ◽  
Author(s):  
Dimitriya H. Garvanska ◽  
Jakob Nilsson

Abstract Kinetochores are instrumental for accurate chromosome segregation by binding to microtubules in order to move chromosomes and by delaying anaphase onset through the spindle assembly checkpoint (SAC). Dynamic phosphorylation of kinetochore components is key to control these activities and is tightly regulated by temporal and spatial recruitment of kinases and phosphoprotein phosphatases (PPPs). Here we focus on PP1, PP2A-B56 and PP2A-B55, three PPPs that are important regulators of mitosis. Despite the fact that these PPPs share a very similar active site, they target unique ser/thr phosphorylation sites to control kinetochore function. Specificity is in part achieved by PPPs binding to short linear motifs (SLiMs) that guide their substrate specificity. SLiMs bind to conserved pockets on PPPs and are degenerate in nature, giving rise to a range of binding affinities. These SLiMs control the assembly of numerous substrate specifying complexes and their position and binding strength allow PPPs to target specific phosphorylation sites. In addition, the activity of PPPs is regulated by mitotic kinases and inhibitors, either directly at the activity level or through affecting PPP–SLiM interactions. Here, we discuss recent progress in understanding the regulation of PPP specificity and activity and how this controls kinetochore biology.


1997 ◽  
Vol 13 (3) ◽  
pp. 195-205 ◽  
Author(s):  
Marit Sorensen

Adherence to lifestyle changes - beginning to exercise, for example - is assumed to be mediated by self-referent thoughts. This paper describes a pilot study and three studies conducted to develop and validate a questionnaire for adults to determine their self-perceptions related to health-oriented exercise. The pilot study identified items pertinent to the domains considered important in this context, and began the process of selecting items. Study 2 examined the factor structure, reduced the number of items, determined the internal consistency of the factors, and explored the discriminative validity of the questionnaire as to physical activity level and gender. Four factors with a total of 24 items were accepted, measuring mastery of exercise, body perception, social comfort/discomfort in the exercise setting, and perception of fitness. All subscales had acceptable internal consistencies. Preliminary validity was demonstrated by confirming hypothesized differences in scores as to gender, age, and physical activity level. The third study examined and demonstrated convergent validity with similar existing subscales. The fourth study examined an English-language version of the questionnaire, confirming the existence of the factors and providing preliminary psychometric evidence of the viability of the questionnaire.


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