Supplemental Material for Neuropsychological Assessment of Mild Cognitive Impairment in Latinx Adults: A Scoping Review

Background: Yog and nutrition have been placed in the limelight since an extensive era for the management of all-cause cognitive impairment. As the global population is ageing rapidly as exhibited that over two billion indi- viduals will be crossing 60 years by 2050, the rate of cognitive decline or impairment will also be a challenge to the healthcare providers. Methodology: The main aim of the present review is to examine the promising benefits of Yog and ancient Indian nutrition science in the overall management of early and mild cognitive impairment and dementia. Many ancient classical Indian texts such as Gherand Samhita, Patanjali Yoga sutra, Charak Samhita, Sushruta Samhita etc., have been extensively referred for the current scoping review. Keywords: Yog, Indian dietetics, Mild cognitive decline, dementia.

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Korean Traditional Medicine in Treating Patients with Mild Cognitive Impairment: A Multicenter Prospective Observational Case Series

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2020/4323989 ◽

2020 ◽

Vol 2020 ◽

pp. 1-12

Author(s):

Yujin Choi ◽

Young-Eun Kim ◽

Ui Min Jerng ◽

Hwan Kim ◽

Sung Ik Lee ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Herbal Medicine ◽

Neuropsychological Assessment ◽

Clinical Setting ◽

Case Series ◽

Cognitive Disorders ◽

Mean Difference ◽

Korean Medicine ◽

The Real

In Korea, patients with mild cognitive impairment can choose to receive treatment of Korean medicine, and Korean medicine hospitals provide specialized medical care for the prevention and management of cognitive disorders. The aim of the study is to explore the role of Korean medicine therapy for patients with mild cognitive impairment in a real clinical setting. Fifteen patients with amnestic mild cognitive impairment were enrolled in this prospective observational study in three Korean medicine hospitals. Korean medicine treatments were delivered by experienced professionals and not restricted to standardized treatment. Outcome measures were prospectively planned to examine the Korean-Montreal Cognitive Assessment (K-MoCA), Korean-Mini Mental State Examination (K-MMSE), and other detailed neuropsychological assessment at the baseline and after 12 and 24 weeks of treatment. Korean medicine treatment for MCI treatment in the real-world clinical setting included herbal medicine and acupuncture. The most frequently used herbs in herbal decoctions were Acori Graminei Rhizoma, Polygalae Radix, and Poria Sclerotium Cum Pini Radix. The herbal medicine formulae used in this study were classified into three categories: tonifying Qi (33.3%), tonifying kidney (46.7%), and calming liver (20%) formulae. In the cognitive ability assessment, the K-MoCA score significantly improved after treatment (mean difference 2.6; 95% CI: 1.3 to 3.9, p=0.001). The K-MMSE score slightly increased after treatment; however, the improvement was not statistically significant (mean difference 0.8; 95% CI: −0.5 to 2.0, p=0.195). In detailed neuropsychological assessment, the cognitive domains of executive functions and memory after the treatment were distinctively improved. In this prospective observational case series, we could see the real clinical environments of treating patients with mild cognitive impairment in Korean medicine hospitals. Patients treated with Korean medicine showed improved results in the neuropsychological assessment after 12 and 24 weeks.

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The Development and Validation of a Neuropsychological Assessment for Mild Cognitive Impairment of Filipino Older Adults

Ageing International ◽

10.1007/s12126-012-9145-4 ◽

2012 ◽

Vol 38 (4) ◽

pp. 271-327

Author(s):

Angelina M. Julom

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Neuropsychological Assessment ◽

Development And Validation

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P3-316: Neuropsychological Assessment of Mild Cognitive Impairment, Dementia and Psychiatric Disorder

Alzheimer s & Dementia ◽

10.1016/j.jalz.2016.06.1980 ◽

2016 ◽

Vol 12 ◽

pp. P965-P965

Author(s):

Ebru Karakoc ◽

Banu Cangoz ◽

Kaynak Selekler

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Psychiatric Disorder ◽

Neuropsychological Assessment

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Predicting outcome in mild cognitive impairment: 4-year follow-up study

The British Journal of Psychiatry ◽

10.1192/bjp.bp.110.077958 ◽

2010 ◽

Vol 197 (2) ◽

pp. 135-140 ◽

Cited By ~ 24

Author(s):

Jane A. Lonie ◽

Mario A. Parra-Rodriguez ◽

Kevin M. Tierney ◽

Lucie L. Herrmann ◽

Claire Donaghey ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Neuropsychological Assessment ◽

Verbal Learning ◽

Cognitive Screening ◽

Prognostic Information ◽

Predictive Values ◽

Diagnosis And Prognosis ◽

Demographic Indices ◽

Sensitivity Specificity

BackgroundCognitive impairment precedes the diagnosis of Alzheimer's disease. It is unclear which psychometric measures predict dementia, and what cut-off points should be used. Replicable cognitive measures to provide information about differential diagnosis and prognosis would be clinically useful.AimsIn a prospective cohort study we investigated which measures distinguish between individuals with amnestic mild cognitive impairment (aMCI) that converts to dementia and those whose impairment does not, and which combination of measures best predicts the fate of people with aMCI.MethodForty-four participants with aMCI underwent extensive neuropsychological assessment at baseline and annually thereafter for an average of 4 years. Differences in baseline cognitive performance of participants who were converters and non-converters to clinically diagnosed dementia were analysed. Classification accuracy was estimated by sensitivity, specificity, positive and negative predictive values and using logistic regression.ResultsForty-one percent of participants had progressed to dementia by the end of study, with a mean annual conversion rate of 11%. Most (63%) showed persisting or progressive cognitive impairment, irrespective of diagnosis. The Addenbrooke's Cognitive Examination together with the discrimination index of the Hopkins Verbal Learning Test – Revised (but none of the demographic indices) differentiated the participants who were converters from the non-converters at baseline with 74% accuracy.ConclusionsTargeted neuropsychological assessment, beyond simple cognitive screening, could be used in clinical practice to provide individuals with aMCI with prognostic information and aid selective early initiation of monitoring and treatment among those who progress towards a clinically diagnosable dementia.

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